Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicholas B. Miner"'
Publikováno v:
J Pharmacol Exp Ther
Methamphetamine (MA) impairs vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function and expression, increasing intracellular DA levels that lead to neurotoxicity. The trace amine–associated receptor 1 (TAAR1) is activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7e56b441704a4b1f5a3a3a0d2520d3
https://doi.org/10.1124/jpet.119.258970
https://doi.org/10.1124/jpet.119.258970
Publikováno v:
Drug and Alcohol Dependence. 227:108974
Background High doses of the synthetic opioid fentanyl cause rapid and sustained vocal cord closure (VCC) leading to airway obstruction that prevents overdose victims from breathing. This airway effect is not caused by morphine-derived opiates (e.g.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654c48e61fb66668c9353fc929761dee
https://doi.org/10.1016/j.drugalcdep.2021.108974
https://doi.org/10.1016/j.drugalcdep.2021.108974
Publikováno v:
NeuroToxicology. 63:57-69
Trace amine-associated receptor 1 (TAAR1) is activated by methamphetamine (MA) and modulates dopaminergic (DA) function. Although DA dysregulation is the hallmark of MA-induced neurotoxicity leading to behavioral and cognitive deficits, the intermedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db17b00029e2ad9fc9d1634ccc54742
https://doi.org/10.1016/j.neuro.2017.09.006
https://doi.org/10.1016/j.neuro.2017.09.006
Publikováno v:
Neurotoxicology and Teratology. 61:74-81
The rise in popularity of substituted methcathinones (aka “bath salts”) has increased the focus on their neurotoxic effects. Two commonly abused methcathinones, 3,4-methylenedioxymethcathinone (methylone, MDMC) and 3,4-methylenedioxypyrovalerone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab8c402d524c1a037955886081011a0
https://doi.org/10.1016/j.ntt.2017.02.003
https://doi.org/10.1016/j.ntt.2017.02.003
Publikováno v:
Genes Brain Behav
Mice selectively bred for high methamphetamine (MA) drinking (MAHDR), compared to mice bred for low MA drinking (MALDR), exhibit greater sensitivity to MA reward and insensitivity to aversive and hypothermic effects of MA. Previous work identified th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4c19ce3679c8b611ec61d0991494dd
https://doi.org/10.1111/gbb.12640
https://doi.org/10.1111/gbb.12640
Methamphetamine (MA) is highly addictive and neurotoxic, causing cell death in humans and in rodent models. MA, along with many of its analogs, is an agonist at the G protein-coupled trace amine-associated receptor 1 (TAAR1). TAAR1 activation protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db606ac5cb00b619f8b8b6d61d0ebf7e
https://europepmc.org/articles/PMC6744391/
https://europepmc.org/articles/PMC6744391/
