Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicholas Apostolopoulos"'
Autor:
Brian Thompson, Nicholas Katsanis, Nicholas Apostolopoulos, David C. Thompson, Daniel W. Nebert, Vasilis Vasiliou
Publikováno v:
Human Genomics, Vol 13, Iss 1, Pp 1-15 (2019)
Abstract Retinoic acid (RA) is a potent morphogen required for embryonic development. RA is formed in a multistep process from vitamin A (retinol); RA acts in a paracrine fashion to shape the developing eye and is essential for normal optic vesicle a
Externí odkaz:
https://doaj.org/article/f308f0d3cc834174ba2f7357e68fa7f9
Autor:
Wendy F. Linderman, Nicholas Apostolopoulos, Anand D. Gopal, John A. Encandela, Christopher C. Teng, Kristen H. Nwanyanwu, Susan H. Forster
Publikováno v:
Journal of Academic Ophthalmology, Vol 10, Iss 01, Pp e122-e126 (2018)
Abstract Problem Health disparities among racial and ethnic groups exist in the United States despite improvements in health status and access to care. These inequalities may be reduced by increasing minority physician recruitment; however, how bes
Externí odkaz:
https://doaj.org/article/f78e67eff7144316ba2c99386adb9e9b
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1004013 (2013)
Homolog pairing, which plays a critical role in meiosis, poses a potential risk if it occurs in inappropriate tissues or between nonallelic sites, as it can lead to changes in gene expression, chromosome entanglements, and loss-of-heterozygosity due
Externí odkaz:
https://doaj.org/article/121073eeb901426fadf8d7cc49097536
Publikováno v:
Journal of Current Glaucoma Practice. 16:195-198
Autor:
Kevin L. Schey, Brian Thompson, Ying Chen, Emily A. Davidson, Vasilis Vasiliou, Jaya Prakash Golla, David J. Orlicky, Rolando Garcia-Milian, David C. Thompson, Nicholas Apostolopoulos
Publikováno v:
Ocul Surf
Purpose The purpose of this study was to elucidate the role and molecular consequences of impaired glutathione (GSH) biosynthesis on eye development. Methods GSH biosynthesis was impaired in surface ectoderm-derived ocular tissues by crossing Gclcf/f
Autor:
Nicholas Apostolopoulos, K Matthew McKay, Brian Chou, Thellea K Leveque, Russell N. Van Gelder
Publikováno v:
Ocular Immunology and Inflammation. 30:1721-1725
To report the clinical course of patients with ocular inflammatory disease treated with adalimumab in whom anti-adalimumab antibodies (AAA) were detected.Single center case series.Eight patients with initial response to adalimumab developed a disease
Publikováno v:
BMJ Case Reports. 15:e244196
Ocular symptoms are a common reason for patients to present to the emergency department or to their primary care physician. Though often benign, these symptoms can also be an early manifestation of systemic disease. We report the case of a patient wh
Autor:
Nicholas Apostolopoulos, Vasilis Vasiliou, David C. Thompson, Nicholas Katsanis, Brian Thompson, Daniel W. Nebert
Publikováno v:
Human Genomics
Human Genomics, Vol 13, Iss 1, Pp 1-15 (2019)
Human Genomics, Vol 13, Iss 1, Pp 1-15 (2019)
Retinoic acid (RA) is a potent morphogen required for embryonic development. RA is formed in a multistep process from vitamin A (retinol); RA acts in a paracrine fashion to shape the developing eye and is essential for normal optic vesicle and anteri
Autor:
Amit Reddy, K Matthew McKay, Cecilia S Lee, Huy V. Nguyen, Megan Lacy, Mohammad Dahrouj, Kathryn L. Pepple, Nicholas Apostolopoulos, Marian Blazes, Aaron Y. Lee
Publikováno v:
JAMA Ophthalmology. 139:887
Importance Big data studies may allow for the aggregation of patients with rare diseases such as uveitis to answer important clinical questions. Standardization of uveitis-related variables will be necessary, including the International Statistical C
Autor:
Brian Thompson, Emily A. Davidson, Nicholas Apostolopoulos, David C. Thompson, Nicholas Katsanis, Vasilis Vasiliou, J. Philippe, Yingtai Chen, David M. Anderson, Jaya Prakash Golla, David J. Orlicky, Kevin L. Schey
Glutamate cysteine ligase catalytic subunit (Gclc) is the catalytic subunit for the glutamate-cysteine ligase (Gcl) enzyme. Gcl catalyzes the rate limiting step in glutathione (GSH) synthesis. Gclc is highly expressed in the developing eye. To define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc462f7d7e2027754fc7fc4f0ad42482