Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicholas A. Till"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2b8b15f9082447cbb95bac98faf0631e
Autor:
Saori Suzuki, Jacob B. Geri, Steve D. Knutson, Harris Bell-Temin, Tomokazu Tamura, David F. Fernández, Gabrielle H. Lovett, Nicholas A. Till, Brigitte L. Heller, Jinchao Guo, David W. C. MacMillan, Alexander Ploss
Publikováno v:
Journal of the American Chemical Society. 144(36)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the infectious agent of the COVID-19 pandemic, remains a global medical problem. Angiotensin-converting enzyme 2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8744b1c6256bc5a6548fa70602fae8
https://pubmed.ncbi.nlm.nih.gov/36049228
https://pubmed.ncbi.nlm.nih.gov/36049228
Publikováno v:
Journal of the American Chemical Society. 143:9332-9337
Here we report the use of pulse radiolysis and spectroelectrochemistry to generate low-valent nickel intermediates relevant to synthetically important Ni-catalyzed cross-coupling reactions and interrogate their reactivities toward comproportionation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7581877793bdc62cb0d65899e49cd4a
https://doi.org/10.1021/jacs.1c04652
https://doi.org/10.1021/jacs.1c04652
Autor:
Adrian Tomkinson, Gary Phillips, Jayaraman Chandrasekhar, Nicholas Alexander Till, Leena Patel, Jia Hao, Jennifer Treiberg, Joseph Therrien, Kathleen S. Keegan, Mary E. McGrath, Sedillo Kassandra F, Fatima Arjmand, Yelena Zherebina, Stephane Perreault, David Koditek, Clinton K. Matson, Eve-Irene Lepist
Publikováno v:
ACS Med Chem Lett
[Image: see text] A series of PI3Kβ selective inhibitors derived from a novel 4-(1H-benzo[d]imidazol-1-yl)quinoline chemotype has been rationally designed. Crucial to achieving the desired selectivity over the other class I PI3K isoforms, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141717e365da34c534fb82eddbca0b95
https://doi.org/10.1021/acsmedchemlett.0c00095
https://doi.org/10.1021/acsmedchemlett.0c00095
Autor:
Sophie G. Bender, Nicholas A. Till, Sky Price, Rebecca Lyn LaLonde, Rachel Yahn, Sophia Varady
Publikováno v:
Bioorganicmedicinal chemistry letters. 52
The repurposing of old drugs for new treatments has recently garnered increased attention in the face of new diseases and declining productivity of the pharmaceutial industry. This report draws attention to potential opportunities hiding in plain sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c057d59f9225e70c37cd7660afaa93f
https://pubmed.ncbi.nlm.nih.gov/34592434
https://pubmed.ncbi.nlm.nih.gov/34592434
Publikováno v:
Journal of the American Chemical Society. 142(37)
The combined use of reaction kinetic analysis, ultrafast spectroscopy, and stoichiometric organometallic studies has enabled the elucidation of the mechanistic underpinnings to a photocatalytic C-N cross-coupling reaction. Steady-state and ultrafast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d3ab43075c70447917c688c104ecb7
https://pubmed.ncbi.nlm.nih.gov/32786779
https://pubmed.ncbi.nlm.nih.gov/32786779
Publikováno v:
Journal of the American Chemical Society. 142(10)
We report mechanistic insights into an iridium/nickel photocatalytic C-O cross-coupling reaction from time-resolved spectroscopic studies. Using transient absorption spectroscopy, energy transfer from an iridium photocatalyst to a catalytically relev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9d339cff6b2d186f3f84d6723168cf
https://pubmed.ncbi.nlm.nih.gov/32078316
https://pubmed.ncbi.nlm.nih.gov/32078316
The merger of open- and closed-shell elementary organometallic steps has enabled the selective intermolecular addition of nucleophilic radicals to unactivated alkynes. A range of carboxylic acids can be subjected to a CO(2) extrusion, nickel capture,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1046602f8a23d2af85457b5bc348a24
https://europepmc.org/articles/PMC6607893/
https://europepmc.org/articles/PMC6607893/
