Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nicholas A. Sumpter"'
Autor:
Melissa S. McDaniel, Natalie R. Lindgren, Caitlin E. Billiot, Kristina N. Valladares, Nicholas A. Sumpter, W. Edward Swords
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Stenotrophomonas maltophilia is an emerging opportunistic respiratory pathogen in people with cystic fibrosis (CF). S. maltophilia is frequently observed in polymicrobial infections, and we have previously shown that Pseudomonas aeruginosa p
Externí odkaz:
https://doaj.org/article/070d288f2be846a69a22a6479ccecbeb
Autor:
Min H Chuah, Megan P Leask, Ruth K Topless, Gregory D Gamble, Nicholas A Sumpter, Lisa K Stamp, Tony R Merriman, Nicola Dalbeth
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background Alcohol consumption is a risk factor for hyperuricaemia and gout. Multiple single-nucleotide polymorphisms (SNPs) have been identified as associated with both alcohol consumption and serum urate or gout in separate genome-wide ass
Externí odkaz:
https://doaj.org/article/18374dbc3e0b4c9eab56923d21d4cba1
Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis
Autor:
Asim K. Mandal, Megan P. Leask, Nicholas A. Sumpter, Hyon K. Choi, Tony R. Merriman, David B. Mount
Publikováno v:
Journal of the American Society of Nephrology. 34:451-466
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad632f2d01bc2da232f14af36da15b5
https://doi.org/10.1681/asn.0000000000000054
https://doi.org/10.1681/asn.0000000000000054
Autor:
Nicholas A. Sumpter, Riku Takei, Murray Cadzow, Ruth K. G. Topless, Amanda J. Phipps‐Green, Rinki Murphy, Janak de Zoysa, Huti Watson, Muhammad Qasim, Alexa S. Lupi, Abhishek Abhishek, Mariano Andrés, Tania O. Crișan, Michael Doherty, Lennart Jacobsson, Matthijs Janssen, Tim L. Jansen, Leo A. B. Joosten, Meliha Kapetanovic, Frédéric Lioté, Hirotaka Matsuo, Geraldine M. McCarthy, Fernando Perez‐Ruiz, Philip Riches, Pascal Richette, Edward Roddy, Blanka Stiburkova, Alexander So, Anne‐Kathrin Tausche, Rosa J. Torres, Till Uhlig, Tanya J. Major, Lisa K. Stamp, Nicola Dalbeth, Hyon K. Choi, Ana I. Vazquez, Megan P. Leask, Richard J. Reynolds, Tony R. Merriman
Publikováno v:
Arthritis & Rheumatology, 75, 816-825
Arthritis & Rheumatology, 75, 5, pp. 816-825
Arthritis & Rheumatology, 75, 5, pp. 816-825
Item does not contain fulltext OBJECTIVE: To determine whether a gout polygenic risk score (PRS) is associated with age at gout onset and tophaceous disease in European, East Polynesian, and West Polynesian men and women with gout. METHODS: A 19-vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237258ce0f3468815af550aa92386a3d
https://hdl.handle.net/2066/292878
https://hdl.handle.net/2066/292878
Autor:
Melissa S. McDaniel, Natalie R. Lindgren, Caitlin E. Billiot, Kristina N. Valladares, Nicholas A. Sumpter, W. Edward Swords
Publikováno v:
Microbiology spectrum.
Stenotrophomonas maltophilia is an emerging opportunistic respiratory pathogen in people with cystic fibrosis (CF). S. maltophilia is frequently observed in polymicrobial infections, and we have previously shown that Pseudomonas aeruginosa promotes c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f78c53c4530f9cdd5bdd5c3bf1a792a
https://pubmed.ncbi.nlm.nih.gov/36472421
https://pubmed.ncbi.nlm.nih.gov/36472421
Autor:
Alexa S Lupi, Nicholas A Sumpter, Megan P Leask, Justin O’Sullivan, Tayaza Fadason, Gustavo de los Campos, Tony R Merriman, Richard J Reynolds, Ana I Vazquez
Publikováno v:
G3 Genes|Genomes|Genetics. 12
Hyperuricemia (serum urate >6.8 mg/dl) is associated with several cardiometabolic and renal diseases, such as gout and chronic kidney disease. Previous studies have examined the shared genetic basis of chronic kidney disease and hyperuricemia in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec607fcac11255772ff18848b9b7317
https://doi.org/10.1093/g3journal/jkac158
https://doi.org/10.1093/g3journal/jkac158
Autor:
Hwasoon Kim, Jasvinder A. Singh, S. Louis Bridges, Ana I. Vazquez, M. Ryan Irvin, Alexa S Lupi, Richard J. Reynolds, Donna K. Arnett, Tony R. Merriman, Nicholas A Sumpter
Publikováno v:
Eur J Hum Genet
Hypertension, obesity, chronic kidney disease and type 2 diabetes are comorbidities that have very high prevalence among persons with hyperuricemia (serum urate > 6.8 mg/dL) and gout. Here we use multivariate genetic models to test the hypothesis tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3759ca92a3cfde41cdb772de9cf782f
https://doi.org/10.1038/s41431-021-00830-z
https://doi.org/10.1038/s41431-021-00830-z
Autor:
Nicola L. Hawley, J. A. Moors, Murray Cadzow, J. de Zoysa, Sally P.A. McCormick, Daniel E. Weeks, Tony R. Merriman, B. Morgan, Nicholas A Sumpter, J. Z. Zhang, Ruth Topless, M. Taumoepeau, Guangyun Sun, Lisa K. Stamp, R. Dekar, F. King, M. Krishnan, Ryan L. Minster, Stephen T. McGarvey, Megan Leask, Rinki Murphy, Satupaitea Viali, Jenna C. Carlson, Phillip Wilcox, Emily M. Russell, Marilyn E. Merriman, John Tuitele, Take Naseri, Matthew J. Bixley, Nicola Dalbeth, Riku Takei, Hong Cheng, Tanya J Major, Amanda Phipps-Green, M. Rutledge, Muagututi’a S. Reupena
Sequencing ofCETPin Māori and Pacific peoples identified a common (MAF ∼2.4%-5.4%) population-specific missense variant (rs1597000001,CETP:c.530C>T p.Pro177Leu) that associates with higher HDL-C levels ([95% CI 0.211; 0.260]) and lower LDL-C ([95%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6db784757fa7eeead0e3d5c94472c96
https://doi.org/10.1101/2021.09.11.21263438
https://doi.org/10.1101/2021.09.11.21263438
Autor:
Riku, Takei, Nicholas A, Sumpter, Amanda, Phipps-Green, Murray, Cadzow, Ruth K, Topless, Richard J, Reynolds, Tony R, Merriman
Publikováno v:
Annals of the rheumatic diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ddf85b4da740eb824b1601eabd6ce98
https://pubmed.ncbi.nlm.nih.gov/34112655
https://pubmed.ncbi.nlm.nih.gov/34112655
Autor:
Nicholas A Sumpter, Tony R. Merriman, Tayaza Fadason, Richard J. Reynolds, de los Campos G, Ana I. Vazquez, Megan Leask, Alexa S Lupi, Justin M. O'Sullivan
Hyperuricemia is associated with several cardiometabolic and renal diseases, such as gout and chronic kidney disease. Previous studies have examined the shared genetic basis of chronic kidney disease and hyperuricemia either using single-variant test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85c4ce430df744868beb23da7d4a3fb5
https://doi.org/10.1101/2021.03.31.21254729
https://doi.org/10.1101/2021.03.31.21254729