Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicholas A. P. S. Buss"'
Autor:
Richard T. George, Liron Abuhatzira, Susan M. Stoughton, Sotirios K. Karathanasis, Dewei She, ChaoYu Jin, Nicholas A. P. S. Buss, Rebecca Bakker‐Arkema, Emily L. Ongstad, Michael Koren, Boaz Hirshberg
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 13 (2021)
Background MEDI6012 is recombinant human lecithin cholesterol acyltransferase, the rate‐limiting enzyme in reverse cholesterol transport. Infusions of lecithin cholesterol acyltransferase have the potential to enhance reverse cholesterol transport
Externí odkaz:
https://doaj.org/article/1a70f3f882f34faebeab6817f3357b2e
Autor:
Michael J. Koren, ChaoYu Jin, Rebecca Bakker-Arkema, Liron Abuhatzira, Dewei She, Boaz Hirshberg, Richard T George, Emily L. Ongstad, Nicholas A P S Buss, Susan M Stoughton, Sotirios K. Karathanasis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background MEDI6012 is recombinant human lecithin cholesterol acyltransferase, the rate‐limiting enzyme in reverse cholesterol transport. Infusions of lecithin cholesterol acyltransferase have the potential to enhance reverse cholesterol transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ba2d209839d960299a3b3593e85a51
https://doi.org/10.1161/jaha.119.014572
https://doi.org/10.1161/jaha.119.014572
Autor:
Jiefen Munley, Andrew Whittaker, Nicholas A P S Buss, Ahmad Ebrahimi, David Brott, Amy Pointon, Paul D. Hockings, Joel S. Raichlen, Ali Khalil, Li-Ming Gan, James Cartwright, Christer Gottfridsson, Pavlo Garkaviy, Johannes Wikström, Richard T George
Publikováno v:
Expert opinion on drug safety. 19(3)
Introduction: Drug-induced myocardial dysfunction is an important safety concern during drug development. Oncology compounds can cause myocardial dysfunction, leading to decreased left ventricular ejection fraction and heart failure via several mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1af200432a74ec8f4f3c592c77abbe
https://pubmed.ncbi.nlm.nih.gov/32064957
https://pubmed.ncbi.nlm.nih.gov/32064957
Autor:
Patricia O. Cover, Nicholas A. P. S. Buss, Julia C. Buckingham, Felicity N. E. Gavins, Andrea Terron
Publikováno v:
The FASEB Journal. 29:2930-2942
Hypothalamo-pituitary-adrenocortical dysfunction contributes to morbidity and mortality in a high proportion of patients with sepsis. Here, we provide new insights into the underlying adrenal pathology. Using a murine model of endotoxemia (LPS inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02157d84574c1240504ec47bd9d64f1
https://doi.org/10.1096/fj.14-268375
https://doi.org/10.1096/fj.14-268375
Autor:
Ellen L Hughes, Julia C. Buckingham, Felicity N. E. Gavins, Paul M. Holloway, Stephen J. Getting, Nicholas A. P. S. Buss
Publikováno v:
The FASEB Journal. 26:4977-4989
Unregulated inflammation underlies many diseases, including sepsis. Much interest lies in targeting anti-inflammatory mechanisms to develop new treatments. One such target is the anti-inflammatory protein annexin A1 (AnxA1) and its receptor, FPR2/ALX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69230c13918528956a4e84b31088a729
https://doi.org/10.1096/fj.12-205971
https://doi.org/10.1096/fj.12-205971
Autor:
C. D. John, Julia C. Buckingham, Patricia O. Cover, Felicity N. E. Gavins, Nicholas A. P. S. Buss
Publikováno v:
Current Opinion in Pharmacology. 8:765-776
Annexin A1 (ANXA1, formerly termed lipocortin 1 or macrocortin) is an important protein mediator of the feedback actions of glucocorticoids within the hypothalamo-pituitary-adrenocortical (HPA) axis. Here we consider the mechanisms by which ANXA1 exe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26127ddbc89f79a171ed0dc69a6237ea
https://doi.org/10.1016/j.coph.2008.09.005
https://doi.org/10.1016/j.coph.2008.09.005
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec5c7b8bad421f08e747ccdf94ce4b89
https://doi.org/10.1096/fasebj.25.1_supplement.116.12
https://doi.org/10.1096/fasebj.25.1_supplement.116.12