Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nicholas A. Mignemi"'
Autor:
Stephanie N. Moore-Lotridge, Rivka Ihejirika, Breanne H.Y. Gibson, Samuel L. Posey, Nicholas A. Mignemi, Heather A. Cole, Gregory D. Hawley, Sasidhar Uppuganti, Jeffry S. Nyman, Jonathan G. Schoenecker
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100743- (2021)
Severely injured patients are beleaguered by complications during convalescence, such as dysregulated biomineralization. Paradoxically, severely injured patients experience the loss of bone (osteoporosis), resulting in diminished skeletal integrity a
Externí odkaz:
https://doaj.org/article/920e3118596a47e794aa675459a82da6
Autor:
Masato Yuasa, Masanori Saito, Cesar Molina, Stephanie N Moore-Lotridge, Michael A Benvenuti, Nicholas A Mignemi, Atsushi Okawa, Toshitaka Yoshii, Herbert S Schwartz, Jeffry S Nyman, Jonathan G Schoenecker
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198088 (2018)
Immediately following a fracture, a fibrin laden hematoma is formed to prevent bleeding and infection. Subsequently, the organized removal of fibrin, via the protease plasmin, is essential to permit fracture repair through angiogenesis and ossificati
Externí odkaz:
https://doaj.org/article/bce861b2f0e84359bdfcacdff30ff368
Autor:
Stephanie N Moore, Gregory D Hawley, Emily N Smith, Nicholas A Mignemi, Rivka C Ihejirika, Masato Yuasa, Justin M M Cates, Xulei Liu, Jonathan G Schoenecker
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159624 (2016)
Soft tissue calcification, including both dystrophic calcification and heterotopic ossification, may occur following injury. These lesions have variable fates as they are either resorbed or persist. Persistent soft tissue calcification may result in
Externí odkaz:
https://doaj.org/article/f0a77febd23a4cdbbd635af55a9d465d
Autor:
Nicholas A. Mignemi, Ian M. Williams, Zhengang Xu, Owen P. McGuinness, Joshua A. Beckman, Curtis C. Hughey, David H. Wasserman, P. Mason McClatchey
Publikováno v:
Am J Physiol Endocrinol Metab
These studies test, using intravital microscopy (IVM), the hypotheses that perfusion effects on insulin-stimulated muscle glucose uptake (MGU) are 1) capillary recruitment independent and 2) mediated through the dispersion of glucose rather than insu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a165d2c6eeb5eec6fbcdc29650a73405
https://doi.org/10.1152/ajpendo.00260.2019
https://doi.org/10.1152/ajpendo.00260.2019
Autor:
Breanne H.Y. Gibson, Stephanie N. Moore-Lotridge, Rivka C. Ihejirika, Samuel L. Posey, Jeffry S. Nyman, Heather A. Cole, Jonathan G. Schoenecker, Nicholas A. Mignemi, Sasidhar Uppuganti, Gregory D. Hawley
Publikováno v:
Bone Reports, Vol 14, Iss, Pp 100743-(2021)
Bone Reports
Bone Reports
Severely injured patients are beleaguered by complications during convalescence, such as dysregulated biomineralization. Paradoxically, severely injured patients experience the loss of bone (osteoporosis), resulting in diminished skeletal integrity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f758f7400427fa3b489329710a9e61
http://www.sciencedirect.com/science/article/pii/S2352187220305039
http://www.sciencedirect.com/science/article/pii/S2352187220305039
Autor:
P. Mason McClatchey, Christopher G. Ellis, Thorbjorn Akerstrom, Graham M. Fraser, Daniel Goldman, David H. Wasserman, Zhengeng Xu, Owen P. McGuinness, Ian M. Williams, Curtis C. Hughey, Joshua A. Beckman, Nicholas A. Mignemi, David C. Poole
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 318(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f236bb2a77585149d5d17d9d75f61c94
https://pubmed.ncbi.nlm.nih.gov/32068465
https://pubmed.ncbi.nlm.nih.gov/32068465
Autor:
Masato Yuasa, Joey V. Barnett, Toshitaka Yoshii, Justin M M Cates, A. Robert MacLeod, Rivka C. Ihejirika, William K. Oelsner, Gourab Bhattacharjee, Stephanie N. Moore, Nicholas A. Mignemi, Courtney E. Baker, Jonathan G. Schoenecker, Jay L. Degen, Herbert S. Schwartz, Alexey S. Revenko, Atsushi Okawa, Christopher S. Wallace, Matthew J. Flick
Publikováno v:
Journal of Bone and Mineral Research. 32:294-308
Extensive or persistent calcium phosphate deposition within soft tissues after severe traumatic injury or major orthopedic surgery can result in pain and loss of joint function. The pathophysiology of soft tissue calcification, including dystrophic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393e2f6899d739e8cd2f05e46d5c8389
https://doi.org/10.1002/jbmr.2973
https://doi.org/10.1002/jbmr.2973
Autor:
Ian M. Williams, Owen P. McGuinness, David H. Wasserman, Nicholas A. Mignemi, Joshua A. Beckman, Penn Mason Mcclatchey, Curtis C. Hughey
Publikováno v:
Diabetes. 68
Objective: It has been proposed that the microcirculation contributes to insulin-stimulated muscle glucose uptake (MGU) by recruiting capillaries and thus enhancing the dispersion of insulin from capillaries into interstitium. This theory contrasts w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c67629b347ee6570f6eb5e08e5e552
https://doi.org/10.2337/db19-172-or
https://doi.org/10.2337/db19-172-or
Publikováno v:
Diabetes. 68
Diabetes and obesity cost the American healthcare system in excess of $322 billion dollars annually. Currently, one of the most effective treatments for obesity and metabolic disorders is bariatric surgery. Bariatric surgery leads to almost immediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25bbfa01f21ae88b30547c879b098100
https://doi.org/10.2337/db19-1820-p
https://doi.org/10.2337/db19-1820-p
Autor:
Craig L. Duvall, Ian M. Williams, Owen P. McGuinness, P. Mason McClatchey, Kristen E. Syring, Nicholas A. Mignemi, Kameron V. Kilchrist, David H. Wasserman, Bryan A. Millis
Publikováno v:
Am J Physiol Endocrinol Metab
Sepsis costs the healthcare system $23 billion annually and has a mortality rate between 10 and 40%. An early indication of sepsis is the onset of hyperglycemia, which is the result of sepsis-induced insulin resistance in skeletal muscle. Previous in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db9f29bdc815af4ca289f959cb454dd
https://doi.org/10.1096/fasebj.2019.33.1_supplement.685.4
https://doi.org/10.1096/fasebj.2019.33.1_supplement.685.4