Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nicholas A. Egan"'
Autor:
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M. Guerrero, Nicholas A. Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S. Stephen Yi, Ken Chen, Daniel J. McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Host anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely unknown due to the biases of previous large-scale studies toward pro-viral host factors. To fill in this knowledge gap, we perform a genome-wide CR
Externí odkaz:
https://doaj.org/article/40cc73e86a42414c8dbcd229f50f5fe6
Autor:
Yuan Chen, Jiakai Hou, Leilei Shi, Ke Pan, Ritu Bohat, Nicholas A. Egan, Jodi A. McKenzie, Rina M. Mbofung, Leila J. Williams, Zhenhuang Yang, Xiaofang Liang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Despite approval of immunotherapy for a wide range of cancers, the majority of patients fail to respond to immunotherapy or relapse following initial response. These failures may be attributed to immunosuppressive mechanisms co-opted by tu
Externí odkaz:
https://doaj.org/article/697d4fd89d6e46368db75489c262a019
Autor:
Sabari Nath Neerukonda, Nicholas A. Egan, Joseph Patria, Imane Assakhi, Phaedra Tavlarides-Hontz, Shannon Modla, Eric R. Muñoz, Matthew B. Hudson, Mark S. Parcells
Publikováno v:
Heliyon, Vol 6, Iss 12, Pp e05669- (2020)
Marek's disease (MD) is an alphaherpesvirus (Marek's disease virus, MDV)-induced pathology of chickens associated with paralysis, immunosuppression, neurological signs, and T-cell lymphomas. MD is controlled in poultry production via live attenuated
Externí odkaz:
https://doaj.org/article/ec6d3d8d2195423bbe379dc39f9e8502
Vaccine Effects on Heterogeneity in Susceptibility and Implications for Population Health Management
Autor:
Kate E. Langwig, Andrew R. Wargo, Darbi R. Jones, Jessie R. Viss, Barbara J. Rutan, Nicholas A. Egan, Pedro Sá-Guimarães, Min Sun Kim, Gael Kurath, M. Gabriela M. Gomes, Marc Lipsitch
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Heterogeneity in host susceptibility is a key determinant of infectious disease dynamics but is rarely accounted for in assessment of disease control measures. Understanding how susceptibility is distributed in populations, and how control m
Externí odkaz:
https://doaj.org/article/2c8075b2870c43a690cf63b855f6c30b
Abstract 4444: Targeting PI3K isoforms to improve the effectiveness of T cell mediated immunotherapy
Autor:
Ritu Bohat, Xiaofang Liang, Chunyu Xu, Yitao Tang, Jiakai Hou, Nicholas A. Egan, Leilei Shi, Ashley Guerrero, Roshni Jaffery, Elizabeth M. Burton, Han Liang, Hussein Tawbi, Michael A. Davies, Weiyi Peng
Publikováno v:
Cancer Research. 83:4444-4444
Hyperactivation of the PI3K pathway has been reported to correlate with resistance to immune checkpoint blockade therapy (ICB) in melanoma, highlighting the therapeutic potential of combining PI3K inhibition (PI3Ki) with ICB. To maximize the clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1343be8ba860ced4544c67f006fb32df
https://doi.org/10.1158/1538-7445.am2023-4444
https://doi.org/10.1158/1538-7445.am2023-4444
Autor:
Cassian Yee, Leila Williams, Navin Varadarajan, Jordi Rodon Ahnert, Jiakai Hou, Rina M. Mbofung, Yunfei Wang, Weiyi Peng, Arash Saeedi, Leilei Shi, Ke Pan, Ritu Bohat, Ming Sun, Nicholas A. Egan, Patrick Hwu, Yiwen Chen, Yuan Chen, Jodi A. McKenzie, Xiaofang Liang, Zhenhuang Yang, Chunyu Xu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundDespite approval of immunotherapy for wide ranges of cancers, the majority of patients fail to respond to immunotherapy or relapse following initial response which is partially attributed to immunosuppression co-opted by tumor cells. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6958468d1d3115cb736c55e7b43e9cf7
https://doaj.org/article/47182d9ef31c41619f53ab7229986336
https://doaj.org/article/47182d9ef31c41619f53ab7229986336
Autor:
Rina M. Mbofung, Yunfei Wang, Xiaofang Liang, Nicholas A. Egan, Arash Saeedi, P. Hwu, Cassian Yee, Leila Williams, Navin Varadarajan, Yuan Chen, Weiyi Peng, Zhenhuang Yang, Jodi A. McKenzie, Ke Pan, Ming Sun, Jiakai Hou, Chunyu Xu, Yiwen Chen, Jordi Rodon Ahnert, Leilei Shi, Ritu Bohat
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
BackgroundDespite approval of immunotherapy for a wide range of cancers, the majority of patients fail to respond to immunotherapy or relapse following initial response. These failures may be attributed to immunosuppressive mechanisms co-opted by tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f69057722713f8f8d638f31ece3abb
https://pubmed.ncbi.nlm.nih.gov/33589527
https://pubmed.ncbi.nlm.nih.gov/33589527
Autor:
Joseph Patria, Nicholas A. Egan, Sabari Nath Neerukonda, Mark S. Parcells, Imane Assakhi, Phaedra Tavlarides-Hontz, Shannon Modla, Matthew B. Hudson, Eric R. Muñoz
Publikováno v:
Heliyon
Heliyon, Vol 6, Iss 12, Pp e05669-(2020)
Heliyon, Vol 6, Iss 12, Pp e05669-(2020)
Marek's disease (MD) is an alphaherpesvirus (Marek's disease virus, MDV)-induced pathology of chickens associated with paralysis, immunosuppression, neurological signs, and T-cell lymphomas. MD is controlled in poultry production via live attenuated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d3eeadc32083669cc11559cba36e69
http://europepmc.org/articles/PMC7734234
http://europepmc.org/articles/PMC7734234
Autor:
Chunyu Xu, Weiyi Peng, Zhenghuang Yang, Nicholas A. Egan, Yiwen Chen, Patrick Hwu, Rina M. Mbofung, Yunfei Wang, Jiakai Hou, Leilei Shi, Arash Saeedi, Ritu Bohat, Jordi Rodon Ahnert, Cassian Yee, Leila Williams, Navin Varadarajan, Jodi A. McKenzie, Ke Pan, Ming Sun, Xiaofang Liang, Yuan Chen
Publikováno v:
Cancer Research. 81:1575-1575
Despite approval of immunotherapy for a wide range of cancers, the majority of patients fail to respond to immunotherapy or relapse following initial response which may be attributed to immunosuppression co-opted by tumor cells. However, it is challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a558eb1288555a59d5def9f3467452
https://doi.org/10.1158/1538-7445.am2021-1575
https://doi.org/10.1158/1538-7445.am2021-1575
Vaccine effects on heterogeneity in susceptibility and implications for population health management
Autor:
Marc Lipsitch, Gael Kurath, Nicholas A. Egan, Jessie R. Viss, Andrew R. Wargo, M. Gabriela M. Gomes, Min Sun Kim, Darbi R. Jones, Pedro Sá-Guimarães, Kate E. Langwig, Barbara J. Rutan
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
mBio, Vol 8, Iss 6, p e00796-17 (2017)
mBio
mBio, Vol 8, Iss 6, p e00796-17 (2017)
mBio
Heterogeneity in host susceptibility is a key determinant of infectious disease dynamics but is rarely accounted for in assessment of disease control measures. Understanding how susceptibility is distributed in populations, and how control measures c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab742a7a30e7cbb4559894f94be33d9b
https://strathprints.strath.ac.uk/73700/1/Langwig_etal_mBio_2017_Vaccine_effects_on_heterogeneity_in_susceptibility_and_implications.pdf
https://strathprints.strath.ac.uk/73700/1/Langwig_etal_mBio_2017_Vaccine_effects_on_heterogeneity_in_susceptibility_and_implications.pdf
