Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicholas A. Devanney"'
Autor:
Sangderk Lee, Nicholas A. Devanney, Lesley R. Golden, Cathryn T. Smith, James L. Schwartz, Adeline E. Walsh, Harrison A. Clarke, Danielle S. Goulding, Elizabeth J. Allenger, Gabriella Morillo-Segovia, Cassi M. Friday, Amy A. Gorman, Tara R. Hawkinson, Steven M. MacLean, Holden C. Williams, Ramon C. Sun, Josh M. Morganti, Lance A. Johnson
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112196- (2023)
Summary: The E4 allele of Apolipoprotein E (APOE) is associated with both metabolic dysfunction and a heightened pro-inflammatory response: two findings that may be intrinsically linked through the concept of immunometabolism. Here, we combined bulk,
Externí odkaz:
https://doaj.org/article/e1c00f972cba4194bdc8ecccacd17804
Autor:
Brandon C. Farmer, Holden C. Williams, Nicholas A. Devanney, Margaret A. Piron, Grant K. Nation, David J. Carter, Adeline E. Walsh, Rebika Khanal, Lyndsay E. A. Young, Jude C. Kluemper, Gabriela Hernandez, Elizabeth J. Allenger, Rachel Mooney, Lesley R. Golden, Cathryn T. Smith, J. Anthony Brandon, Vedant A. Gupta, Philip A. Kern, Matthew S. Gentry, Josh M. Morganti, Ramon C. Sun, Lance A. Johnson
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Cerebral glucose hypometabolism is consistently observed in individuals with Alzheimer’s disease (AD), as well as in young cognitively normal carriers of the Ε4 allele of Apolipoprotein E (APOE), the strongest genetic predictor
Externí odkaz:
https://doaj.org/article/cb9c5a3aaabd427e887297119cecd36d
Autor:
Sangderk Lee, Holden C. Williams, Amy A. Gorman, Nicholas A. Devanney, Douglas A. Harrison, Adeline E. Walsh, Danielle S. Goulding, Tony Tuck, James L. Schwartz, Diana J. Zajac, Shannon L. Macauley, Steven Estus, TCW Julia, Lance A. Johnson, Josh M. Morganti
Publikováno v:
bioRxiv
SummaryApolipoprotein E4 (APOE4) is the strongest risk allele associated with the development of late onset Alzheimer’s disease (AD). Across the CNS, astrocytes are the predominant expressor ofAPOEwhile also being critical mediators of neuroinflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbb7b96ff691f012d4c3107889a13e7
https://europepmc.org/articles/PMC9934552/
https://europepmc.org/articles/PMC9934552/
Autor:
Nicholas A. Devanney, Sangderk Lee, Holden C. Williams, Elizabeth J. Allenger, Cathryn T Smith, Gabriella Morillo Segovia, Adeline E. Walsh, Cassi Friday, Josh M. Morganti, Lance A Johnson
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Sangderk Lee, Nicholas A. Devanney, Lesley R. Golden, Cathryn T. Smith, James L. Schwarz, Adeline E. Walsh, Harrison A. Clarke, Danielle S. Goulding, Elizabeth J. Allenger, Gabriella Morillo-Segovia, Cassi M. Friday, Amy A. Gorman, Tara R. Hawkinson, Steven M. MacLean, Holden C. Williams, Ramon C. Sun, Josh M. Morganti, Lance A. Johnson
SummaryThe E4 allele of Apolipoprotein E (APOE) is associated with both metabolic dysfunction and a heightened pro-inflammatory response – two findings that may be intrinsically linked through the concept of immunometabolism. Here, we combined bulk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f4de5c35528204312724ba96448803
https://doi.org/10.1101/2022.05.17.492361
https://doi.org/10.1101/2022.05.17.492361