Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Nicholas A. Bock"'
Publikováno v:
Journal of Affective Disorders Reports, Vol 15, Iss , Pp 100689- (2024)
Background: Brain imaging studies have thoroughly investigated brain gray matter abnormalities to assess pathophysiological mechanisms underlying psychiatric illnesses, however white matter has only recently been investigated. Abnormalities in myelin
Externí odkaz:
https://doaj.org/article/e06caa4dbf2645fc8ced8a4fff571240
Autor:
Matthew F. Glasser, Timothy S. Coalson, Michael P. Harms, Junqian Xu, Graham L. Baum, Joonas A. Autio, Edward J. Auerbach, Douglas N. Greve, Essa Yacoub, David C. Van Essen, Nicholas A. Bock, Takuya Hayashi
Publikováno v:
NeuroImage, Vol 258, Iss , Pp 119360- (2022)
T1-weighted divided by T2-weighted (T1w/T2w) myelin maps were initially developed for neuroanatomical analyses such as identifying cortical areas, but they are increasingly used in statistical comparisons across individuals and groups with other vari
Externí odkaz:
https://doaj.org/article/1881e790dd474fb8b7f72d77012d133f
Autor:
David Stillo, Ethan Danielli, Rachelle A. Ho, Carol DeMatteo, Geoffrey B. Hall, Nicholas A. Bock, John F. Connolly, Michael D. Noseworthy
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
In the United States, approximately 2.53 million people sustain a concussion each year. Relative to adults, youth show greater cognitive deficits following concussion and a longer recovery. An accurate and reliable imaging method is needed to determi
Externí odkaz:
https://doaj.org/article/f8817ce3991e4e68afa7b1f2a9de25e9
Autor:
Ritesh P. Daya, Jayant Bhandari, Sharnpreet K. Kooner, Joella Ho, Christopher D. Rowley, Nicholas A. Bock, Troy Farncombe, Ram K. Mishra
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
PAOPA, a potent analog of prolyl-leucyl-glycinamide, has shown therapeutic potential at the preclinical stage for dopaminergic related illnesses, including animal models of schizophrenia, Parkinson’s disease and haloperidol-induced extrapyramidal m
Externí odkaz:
https://doaj.org/article/35e1aeacea904b069f84bd70655ba3fc
Autor:
Jee Su Suh, Christopher D Rowley, Manpreet Sehmbi, Christine L Tardif, Luciano Minuzzi, Nicholas A Bock, Benicio N Frey
Publikováno v:
Cerebral Cortex.
Age-related changes of intracortical myelin in bipolar disorder (BD) have been observed to deviate from the quadratic age curve observed in healthy controls (HC), but it is unclear if this holds at varying cortical depths. From BD (n = 44; age range
Autor:
Christopher D. Rowley, Sarah J. Tabrizi, Rachael I. Scahill, Blair R. Leavitt, Raymund A. C. Roos, Alexandra Durr, Nicholas A. Bock
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Huntington’s disease (HD) is a genetic neurodegenerative disorder that is characterized by neuronal cell death. Although medium spiny neurons in the striatum are predominantly affected, other brain regions including the cerebral cortex also degener
Externí odkaz:
https://doaj.org/article/5dec07ffb63d49aab552aecab8b726ca
Autor:
Manpreet Sehmbi, Jee Su Suh, Christopher D. Rowley, Luciano Minuzzi, Flavio Kapczinski, Nicholas A. Bock, Benicio N. Frey
Publikováno v:
Bipolar disordersREFERENCES. 24(5)
Psychosocial functioning in bipolar disorder (BD) persists even during euthymia and has repeatedly been associated with illness progression and cognitive function. Its neurobiological correlates remain largely unexplored. Using a structural covarianc
Autor:
Matthew F. Glasser, Timothy S. Coalson, Michael P. Harms, Junqian Xu, Graham L. Baum, Joonas A. Autio, Edward J. Auerbach, Douglas N. Greve, Essa Yacoub, David C. Van Essen, Nicholas A. Bock, Takuya Hayashi
Publikováno v:
NeuroImage. 258
T1-weighted divided by T2-weighted (T1w/T2w) myelin maps were initially developed for neuroanatomical analyses such as identifying cortical areas, but they are increasingly used in statistical comparisons across individuals and groups with other vari
Autor:
David Bakhshinyan, Ashley A. Adile, Jeff Liu, William D. Gwynne, Yujin Suk, Stefan Custers, Ian Burns, Mohini Singh, Nicole McFarlane, Minomi K. Subapanditha, Maleeha A. Qazi, Parvez Vora, Michelle M. Kameda-Smith, Neil Savage, Kim L. Desmond, Nazanin Tatari, Damian Tran, Mathieu Seyfrid, Kristin Hope, Nicholas A. Bock, Chitra Venugopal, Gary D. Bader, Sheila K. Singh
Publikováno v:
Science Advances
Description
Gene expression profiling of medulloblastoma cells undergoing therapy identifies BPIFB4 as a novel target for recurrent disease.
Medulloblastoma (MB) remains a leading cause of cancer-related mortality among children. The paucit
Gene expression profiling of medulloblastoma cells undergoing therapy identifies BPIFB4 as a novel target for recurrent disease.
Medulloblastoma (MB) remains a leading cause of cancer-related mortality among children. The paucit
Autor:
Christopher Dennis Rowley, Pierre-Louis eBazin, Christine Lucas Tardif, Manpreet eSehmbi, Eyesha eHashim, Nadejda eZaharieva, Benicio eFrey, Lucianno eMinuzzi, Nicholas Adam Bock
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Alterations in the myelination of the cerebral cortex may underlie abnormal cortical function in a variety of brain diseases. Here, we describe a technique for investigating changes in intracortical myelin in clinical populations on the basis of cort
Externí odkaz:
https://doaj.org/article/4538dba44d28437489ba54e830041eff