Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nicholas A Steinmetz"'
Publikováno v:
eLife, Vol 12 (2023)
The ability to associate reward-predicting stimuli with adaptive behavior is frequently attributed to the prefrontal cortex, but the stimulus-specificity, spatial distribution, and stability of prefrontal cue-reward associations are unresolved. We tr
Externí odkaz:
https://doaj.org/article/be5710e5742c458bb8d31593c1070498
Publikováno v:
eLife, Vol 10 (2021)
Correlates of sensory stimuli and motor actions are found in multiple cortical areas, but such correlates do not indicate whether these areas are causally relevant to task performance. We trained mice to discriminate visual contrast and report their
Externí odkaz:
https://doaj.org/article/a77d4f9490c9409ab125f51f02b4c47c
Publikováno v:
eLife, Vol 8 (2019)
In the absence of external stimuli or overt behavior, the activity of the left and right cortical hemispheres shows fluctuations that are largely bilateral. Here, we show that these fluctuations are largely responsible for the variability observed in
Externí odkaz:
https://doaj.org/article/1a3f1425b20749399e8fd820375b921d
Autor:
Carsen Stringer, Marius Pachitariu, Nicholas A Steinmetz, Michael Okun, Peter Bartho, Kenneth D Harris, Maneesh Sahani, Nicholas A Lesica
Publikováno v:
eLife, Vol 5 (2016)
Cortical networks exhibit intrinsic dynamics that drive coordinated, large-scale fluctuations across neuronal populations and create noise correlations that impact sensory coding. To investigate the network-level mechanisms that underlie these dynami
Externí odkaz:
https://doaj.org/article/3f2b79f907e044daaeea1b83f8809b80
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Noise correlations in the neocortex change dynamically with cognitive states. Here the authors show how heterogeneous spatial patterns of noise correlations emerge through interactions of cortical On-Off dynamics, connectivity, and attention.
Externí odkaz:
https://doaj.org/article/107d266418a34ed9b70699873e3dbe7e
Autor:
Christopher P. Burgess, Armin Lak, Nicholas A. Steinmetz, Peter Zatka-Haas, Charu Bai Reddy, Elina A.K. Jacobs, Jennifer F. Linden, Joseph J. Paton, Adam Ranson, Sylvia Schröder, Sofia Soares, Miles J. Wells, Lauren E. Wool, Kenneth D. Harris, Matteo Carandini
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2513-2524 (2017)
Research in neuroscience increasingly relies on the mouse, a mammalian species that affords unparalleled genetic tractability and brain atlases. Here, we introduce high-yield methods for probing mouse visual decisions. Mice are head-fixed, facilitati
Externí odkaz:
https://doaj.org/article/7924016051e04348aeee3c6517391429
Autor:
Min Song, Eun Ju Shin, Hyojung Seo, Alireza Soltani, Nicholas A. Steinmetz, Daeyeol Lee, Min Whan Jung, Se-Bum Paik
Timescales of temporally correlated neural activity vary systematically along the anatomical hierarchy of the primate cortex. Here, we found a similar hierarchical gradient of timescales in intrinsic as well as task-related cortical activities across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49b75a3196e44d00c2d045558fc8a584
https://doi.org/10.1101/2023.05.12.540610
https://doi.org/10.1101/2023.05.12.540610
Autor:
Y Shi, R Zeraati, Alexander Thiele, Anna Levina, Tatiana A. Engel, Tirin Moore, Mark A. Gieselmann, Nicholas A. Steinmetz
Publikováno v:
Nature Communications
Intrinsic timescales characterize dynamics of endogenous fluctuations in neural activity. Variation of intrinsic timescales across the neocortex reflects functional specialization of cortical areas, but less is known about how intrinsic timescales ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518960c4d3cb2fa4ea88255a1517585b
https://hdl.handle.net/21.11116/0000-000C-E88E-F
https://hdl.handle.net/21.11116/0000-000C-E88E-F
Autor:
David J. Ottenheimer, Madelyn M. Hjort, Anna J. Bowen, Nicholas A. Steinmetz, Garret D. Stuber
SummaryThe ability to associate reward-predicting stimuli with adaptive behavior is frequently attributed to the prefrontal cortex, but the stimulus-specificity, spatial distribution, and stability of pre-frontal cue-reward associations are unresolve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800e58e9235fadb86a01d1cb9fd6448c
https://doi.org/10.7554/elife.84604
https://doi.org/10.7554/elife.84604
Autor:
Edward Zagha, Jeffrey C. Erlich, Soohyun Lee, Gyorgy Lur, Daniel H. O'Connor, Nicholas A. Steinmetz, Carsen Stringer, Hongdian Yang
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 8
J Neurosci
J Neurosci
A surprising finding of recent studies in mouse is the dominance of widespread movement-related activity throughout the brain, including in early sensory areas. In awake subjects, failing to account for movement risks misattributing movement-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066458f696a002ceb872c5665c342016
https://escholarship.org/uc/item/8kf402ws
https://escholarship.org/uc/item/8kf402ws