Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicholas A Ruggero"'
Autor:
Miriam V Gutschow, Jacob J Hughey, Nicholas A Ruggero, Bryce T Bajar, Sean D Valle, Markus W Covert
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53222 (2013)
Lipopolysaccharide (LPS), found in the outer membrane of gram-negative bacteria, elicits a strong response from the transcription factor family Nuclear factor (NF)-κB via Toll-like receptor (TLR) 4. The cellular response to lipopolysaccharide varies
Externí odkaz:
https://doaj.org/article/c4e6e4c1301e4ef599c59a934258dd0b
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 10, p e1002746 (2012)
Viral replication relies on host metabolic machinery and precursors to produce large numbers of progeny - often very rapidly. A fundamental example is the infection of Escherichia coli by bacteriophage T7. The resource draw imposed by viral replicati
Externí odkaz:
https://doaj.org/article/6f42bebb8a6648b1ad921a6024d861c1
Autor:
Peter D. Karp, Inbal Maayan, Gwanggyu Sun, Sajia Akhter, Taryn E. Gillies, Daniel Weaver, Heejo Choi, Jerry H. Morrison, Samuel R. Bray, Ingrid M. Keseler, Morgan L. Paull, Ryan K. Spangler, Travis A. Ahn-Horst, Markus W. Covert, Nicholas A. Ruggero, Mialy M. DeFelice, John C. Mason, Javier Carrera, Derek N. Macklin, Keara Michelle Lane, Eran Agmon
Publikováno v:
Science. 369:eaav3751
The extensive heterogeneity of biological data poses challenges to analysis and interpretation. Construction of a large-scale mechanistic model of Escherichia coli enabled us to integrate and cross-evaluate a massive, heterogeneous dataset based on m
Autor:
Derek N, Macklin, Travis A, Ahn-Horst, Heejo, Choi, Nicholas A, Ruggero, Javier, Carrera, John C, Mason, Gwanggyu, Sun, Eran, Agmon, Mialy M, DeFelice, Inbal, Maayan, Keara, Lane, Ryan K, Spangler, Taryn E, Gillies, Morgan L, Paull, Sajia, Akhter, Samuel R, Bray, Daniel S, Weaver, Ingrid M, Keseler, Peter D, Karp, Jerry H, Morrison, Markus W, Covert
Publikováno v:
Science (New York, N.Y.). 369(6502)
The extensive heterogeneity of biological data poses challenges to analysis and interpretation. Construction of a large-scale mechanistic model of
Publikováno v:
Current opinion in biotechnology. 28
Integrated whole-cell modeling is poised to make a dramatic impact on molecular and systems biology, bioengineering, and medicine--once certain obstacles are overcome. From our group's experience building a whole-cell model of Mycoplasma genitalium,
Autor:
Bryce T. Bajar, Jacob J. Hughey, Miriam V. Gutschow, Markus W. Covert, Nicholas A. Ruggero, Sean D. Valle
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e53222 (2013)
PLoS ONE, Vol 8, Iss 1, p e53222 (2013)
Background Lipopolysaccharide (LPS), found in the outer membrane of gram-negative bacteria, elicits a strong response from the transcription factor family Nuclear factor (NF)-κB via Toll-like receptor (TLR) 4. The cellular response to lipopolysaccha
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 10, p e1002746 (2012)
PLoS Computational Biology
PLoS Computational Biology
Viral replication relies on host metabolic machinery and precursors to produce large numbers of progeny - often very rapidly. A fundamental example is the infection of Escherichia coli by bacteriophage T7. The resource draw imposed by viral replicati