Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.

Autor: Vasso Makrantoni, Stephen J Corbishley, Najma Rachidi, Nicholas A Morrice, David A Robinson, Michael J R Stark

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e89399 (2014)

The chromosomal passenger complex (CPC) is a key regulator of eukaryotic cell division, consisting of the protein kinase Aurora B/Ipl1 in association with its activator (INCENP/Sli15) and two additional proteins (Survivin/Bir1 and Borealin/Nbl1). Her

Externí odkaz: https://doaj.org/article/ebfa2001333c49a2b68263fb0e19e7ba

Corrigendum to 'Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR' [DNA Repair 6 (2007) 1536-1544]

Autor: John Rouse, Paul A. Jowsey, Nicholas A. Morrice, Hilary MacLauchlan, Rachel Toth, C. James Hastie

Publikováno v: DNA repair. 65

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71c2bbe4a0232d21ec798f4bd500f51
https://pubmed.ncbi.nlm.nih.gov/17553757

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

Autor: Cora Weigert, Kei Sakamoto, Katrin Spengler, Mark Peggie, Karina Mariño, Olga Göransson, Franck Vandermoere, Anne Knierim, Darya Zibrova, Benoit Viollet, Nicholas A. Morrice, Regine Heller

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2017, 474 (6), pp.983-1001. ⟨10.1042/BCJ20160980⟩
Biochem. J. 474, 983-1001 (2017)

Activation of AMP-activated protein kinase (AMPK) in endothelial cells regulates energy homeostasis, stress protection and angiogenesis, but the underlying mechanisms are incompletely understood. Using a label-free phosphoproteomic analysis, we ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9cf91a6472ceb8ae0ea89dadd05423
https://hal.archives-ouvertes.fr/hal-02366087/document

Blebs produced by actin–myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs

Autor: S Al Zander, Willy V. Bienvenut, June Munro, Grant R Wickman, Nicholas A. Morrice, David Sumpton, Andrzej Mleczak, S Schumacher, Katerina Mardilovich, Nicola Rath, Michael F. Olson, Linda Julian

Publikováno v: Cell Death and Differentiation

Apoptosis is a fundamental homeostatic mechanism essential for the normal growth, development and maintenance of every tissue and organ. Dying cells have been defined as apoptotic by distinguishing features, including cell contraction, nuclear fragme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d72dce711d9751ff08c5a7e8c06bce2
http://europepmc.org/articles/PMC3770329

cAMP-elevation mediated by β-adrenergic stimulation inhibits salt-inducible kinase (SIK) 3 activity in adipocytes

Autor: Helena A. Jones, Nicholas A. Morrice, Olga Göransson, Emma Henriksson, Christine Berggreen

Publikováno v: Cellular Signalling. 24:1863-1871

Salt-inducible kinase (SIK) 3 is a virtually unstudied, ubiquitously expressed serine/threonine kinase, belonging to the AMP-activated protein kinase (AMPK)-related family of kinases, all of which are regulated by LKB1 phosphorylation of a threonine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72dcc7b06c78f49712b01490801ca07f
https://doi.org/10.1016/j.cellsig.2012.05.001