Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicholas A Dompe"'
Autor:
Jennifer E Deal, Geoffrey Duyk, Kyle A. Edgar, Kevin P Bogart, Christopher G. Winter, Matthew A Singer, Daniel Tim Curtis, Robert Fawcett, Lory R Tan, Valentina Vysotskaia, Wesley Y Miyazaki, Casey Kopczynski, Kari Huppert, Marie Marcinko, Elizabeth Howie, Millicent A Winner, Doua Thao, Kellie Whittaker, Nicholas A Dompe, Jonathan Margolis, Deanna Grant, Rachel S. Andrade, Gregory D. Plowman, Marcia Belvin, Mariano Tabios, Megan E Deal-Herr, Helen Francis-Lang, Amanda Norton, Lora Zhao, Stephanie A. Robertson, Annette L. Parks, Lori Friedman, Kenneth J. Shaw, Kevin R. Cook, Keith Killpack, Brett Milash, Thomas C. Kaufman
Publikováno v:
Nature Genetics. 36:288-292
In fruit fly research, chromosomal deletions are indispensable tools for mapping mutations, characterizing alleles and identifying interacting loci. Most widely used deletions were generated by irradiation or chemical mutagenesis. These methods are l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477f9bbffc7978d9ed6722537bf31237
https://doi.org/10.1038/ng1312
https://doi.org/10.1038/ng1312
Autor:
Ross Buchholz, Jonathan Margolis, Kimberly Greer, Carol M. Singh, Lory R Tan, Lynn M Stevens, Cathy Erickson, Julie Mazzotta, Wesley Y Miyazaki, Lora Zhao, Angela Chong, Robert Fawcett, William W Fisher, Lai Man Cheung, Keith Killpack, Alex Laufer, Geoffrey Duyk, Stephen T Thibault, Candace Swimmer, Matthew A Singer, Helen Francis-Lang, Casey Kopczynski, Elizabeth Howie, Lakshmi Jakkula, Madelyn Robin Demsky, Brett Milash, Irena Zakrajsek, Richard Benn Abegania Ventura, Feng Chen, Nicholas A Dompe, Margaret L. Winberg, Alesa Woo, Lisa Ryner, Daniel Joo, Ronald D. Smith, Stephanie R Hartouni, Christiana Stuber
Publikováno v:
Nature Genetics. 36:283-287
With the availability of complete genome sequence for Drosophila melanogaster, one of the next strategic goals for fly researchers is a complete gene knockout collection. The P-element transposon, the workhorse of D. melanogaster molecular genetics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::790ac1443a02e6b74ca89a02a2a92ea2
https://doi.org/10.1038/ng1314
https://doi.org/10.1038/ng1314
Abstract B22: Potential combinatorial strategies to overcome drug resistance in BRAF-mutant melanoma
Autor:
Nicholas A. Dompe, Eva Lin, Jing Peng, Grace Chan, Janet Tien, Mark Merchant, Richard Bourgon, Jeffrey Settleman, Timothy Wilson, Richard M. Neve
Publikováno v:
Clinical Cancer Research. 21:B22-B22
RAF and MEK inhibitors are used to target malignant melanomas harbouring BRAF V600E mutations, but resistance to these therapies remains a significant challenge. Here we conducted a screen of 450 secreted peptides to identify possible cell-autonomous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aa5effe43dcd64e1704fb32ce42841b
https://doi.org/10.1158/1557-3265.pms14-b22
https://doi.org/10.1158/1557-3265.pms14-b22