Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nicholas A Crossland"'
Autor:
Raveen Rathnasinghe, Lauren A. Chang, Rebecca Pearl, Sonia Jangra, Amy Aspelund, Alaura Hoag, Soner Yildiz, Ignacio Mena, Weina Sun, Madhumathi Loganathan, Nicholas Alexander Crossland, Hans P. Gertje, Anna Elise Tseng, Sadaf Aslam, Randy A. Albrecht, Peter Palese, Florian Krammer, Michael Schotsaert, Thomas Muster, Adolfo García-Sastre
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Influenza viruses pose a threat to public health as evidenced by severe morbidity and mortality in humans on a yearly basis. Given the constant changes in the viral glycoproteins owing to antigenic drift, seasonal influenza vaccines need to
Externí odkaz:
https://doaj.org/article/dccfdfa0d19945a6be803b54e7f7865b
Autor:
Nicholas A Crossland, Cory R Hanks, Jayde A Ferguson, Michael L Kent, Justin L Sanders, Fabio Del Piero
Publikováno v:
Journal of Feline Medicine and Surgery Open Reports, Vol 1 (2015)
Case summary A feral domestic shorthair cat was euthanized owing to acute onset and progression of neurological signs attributed to ethylene glycol toxicity. At post-mortem examination two nodules were identified within the fundus of the stomach. Exa
Externí odkaz:
https://doaj.org/article/64cf8a6aabdf4df9b7cdd0faa03d6ae7
Autor:
Yongzhen Liu, Stephanie Maya, Sebastian Carver, Aoife K. O’Connell, Anna E. Tseng, Hans P. Gertje, Kathleen Seneca, Ronald G. Nahass, Nicholas A. Crossland, Alexander Ploss
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTHepatitis B virus (HBV) infection remains a major public health problem and, in associated co-infection with hepatitis delta virus (HDV), causes the most severe viral hepatitis and accelerated liver disease progression. As a defective satelli
Externí odkaz:
https://doaj.org/article/b3f1e5ed3cf34095926b0a10f4fa94cc
Autor:
Saravanan Subramaniam, Devin Kenney, Archana Jayaraman, Aoife Kateri O’Connell, Sarah Walachowski, Paige Montanaro, Christoph Reinhardt, Giuseppe Colucci, Nicholas A. Crossland, Florian Douam, Markus Bosmann
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Advanced age is associated with an increased susceptibility to Coronavirus Disease (COVID)-19 and more severe outcomes, although the underlying mechanisms are understudied. The lung endothelium is located next to infected epithelial cells and bystand
Externí odkaz:
https://doaj.org/article/96d310ad2ca94a3d983c9a3685c19e7e
Autor:
Nicholas A. Crossland, Samuel Beck, Wei Yu Tan, Ming Lo, Joel B. Mason, Chao Zhang, Weimin Guo, Jimmy W. Crott
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTAging is a strong risk factor for colorectal cancer (CRC). It is well established that gut microbial dysbiosis can play a role in the etiology of CRC. Although the composition of the gut microbial community changes with age and is reported to
Externí odkaz:
https://doaj.org/article/1461af85cb5a4f208b551ef8b6668b61
Autor:
Da-Yuan Chen, Jacquelyn Turcinovic, Shuchen Feng, Devin J. Kenney, Chue Vin Chin, Manish C. Choudhary, Hasahn L. Conway, Marc Semaan, Brianna J. Close, Alexander H. Tavares, Scott Seitz, Nazimuddin Khan, Sebastian Kapell, Nicholas A. Crossland, Jonathan Z. Li, Florian Douam, Susan C. Baker, John H. Connor, Mohsan Saeed
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106634- (2023)
Summary: A simple and robust cell culture system is essential for generating authentic SARS-CoV-2 stocks for evaluation of viral pathogenicity, screening of antiviral compounds, and preparation of inactivated vaccines. Evidence suggests that Vero E6,
Externí odkaz:
https://doaj.org/article/4ef512ed285e4127ae84089843aedd7f
Autor:
Côme J. Thieulent, Wellesley Dittmar, Udeni B. R. Balasuriya, Nicholas A. Crossland, Xue Wen, Juergen A. Richt, Mariano Carossino
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT Several models were developed to study the pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as well as the in vivo efficacy of vaccines and therapeutics. Since wild-type mice are naturally resistant to infection
Externí odkaz:
https://doaj.org/article/2cf2551578444b2aac78c3dd286380c3
Autor:
Yongzhen Liu, Debby Park, Thomas R. Cafiero, Yaron Bram, Vasuretha Chandar, Anna Tseng, Hans P. Gertje, Nicholas A. Crossland, Lishan Su, Robert E. Schwartz, Alexander Ploss
Publikováno v:
JHEP Reports, Vol 4, Iss 9, Pp 100535- (2022)
Background & Aims: HBV exhibits wide genetic diversity with at least 9 genotypes (GTs), which differ in terms of prevalence, geographic distribution, natural history, disease progression, and treatment outcome. However, differences in HBV replicative
Externí odkaz:
https://doaj.org/article/1554fc7886654cae9e56bd1c430ac1fc
Autor:
Lei Wei, Thomas R. Cafiero, Anna Tseng, Hans P. Gertje, Andrew Berneshawi, Nicholas A. Crossland, Alexander Ploss
Publikováno v:
JHEP Reports, Vol 4, Iss 9, Pp 100534- (2022)
Background & Aims: HBV has a narrow host restriction, with humans and chimpanzees representing the only known natural hosts. The molecular correlates of resistance in species that are commonly used in biomedical research, such as mice, are currently
Externí odkaz:
https://doaj.org/article/b24879bf35b2455c990b168a48224d44
Autor:
Da-Yuan Chen, Chue Vin Chin, Devin Kenney, Alexander H. Tavares, Nazimuddin Khan, Hasahn L. Conway, GuanQun Liu, Manish C. Choudhary, Hans P. Gertje, Aoife K. O’Connell, Scott Adams, Darrell N. Kotton, Alexandra Herrmann, Armin Ensser, John H. Connor, Markus Bosmann, Jonathan Z. Li, Michaela U. Gack, Susan C. Baker, Robert N. Kirchdoerfer, Yachana Kataria, Nicholas A. Crossland, Florian Douam, Mohsan Saeed
Publikováno v:
Nature. 615:143-150
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b38361413ea484128a043ed919878160
https://doi.org/10.1038/s41586-023-05697-2
https://doi.org/10.1038/s41586-023-05697-2