Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nicholas A, May"'
Autor:
Peiqi Yin, Nicholas A. May, Laura Sandra Lello, Atef Fayed, M. Guston Parks, Adam M. Drobish, Sainan Wang, Meghan Andrews, Zachary Sticher, Alexander A. Kolykhalov, Michael G. Natchus, George R. Painter, Andres Merits, Margaret Kielian, Thomas E. Morrison
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Chikungunya virus (CHIKV) is an enveloped, positive-sense RNA virus that has re-emerged to cause millions of human infections worldwide. In humans, acute CHIKV infection causes fever and severe muscle and joint pain. Chronic and debilitating
Externí odkaz:
https://doaj.org/article/dfff5e12899b43dd9c8db8e7247e88db
Autor:
Kathryn S Carpentier, Bennett J Davenport, Kelsey C Haist, Mary K McCarthy, Nicholas A May, Alexis Robison, Claudia Ruckert, Gregory D Ebel, Thomas E Morrison
Publikováno v:
eLife, Vol 8 (2019)
The magnitude and duration of vertebrate viremia is a critical determinant of arbovirus transmission, geographic spread, and disease severity. We find that multiple alphaviruses, including chikungunya (CHIKV), Ross River (RRV), and o’nyong ‘nyong
Externí odkaz:
https://doaj.org/article/1bca733072e94419b0e3fbfbf08f37b9
Autor:
Hui Zhang, Evgenia Gerasimovskaya, Mary K. McCarthy, Nicholas A. May, Ram Raj Prasad, Suzette Riddle, B Alexandre McKeon, Sushil Kumar, Min Li, Cheng-Jun Hu, Maria G Frid, Thomas E. Morrison, Kurt R Stenmark
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eab7a321570e36edc4f43bbf10771bc
https://doi.org/10.1165/rcmb.2022-0373oc
https://doi.org/10.1165/rcmb.2022-0373oc
Autor:
David W. Hawman, Julie M. Fox, Alison W. Ashbrook, Nicholas A. May, Kristin M.S. Schroeder, Raul M. Torres, James E. Crowe Jr., Terence S. Dermody, Michael S. Diamond, Thomas E. Morrison
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1326-1338 (2016)
Chikungunya virus (CHIKV) and related alphaviruses cause epidemics of acute and chronic musculoskeletal disease. To investigate the mechanisms underlying the failure of immune clearance of CHIKV, we studied mice infected with an attenuated CHIKV stra
Externí odkaz:
https://doaj.org/article/a0c429574bbd4bd385c377b101b51d3c
Autor:
Kevin J Sokoloski, Lauren M Nease, Nicholas A May, Natasha N Gebhart, Claire E Jones, Thomas E Morrison, Richard W Hardy
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006473 (2017)
Alphaviruses are arthropod-borne viruses that represent a significant threat to public health at a global level. While the formation of alphaviral nucleocapsid cores, consisting of cargo nucleic acid and the viral capsid protein, is an essential mole
Externí odkaz:
https://doaj.org/article/9be5cebb7ebd43c7a2706b30daf0c1f6
Autor:
Alison W. Ashbrook, Anthony J. Lentscher, Paula F. Zamora, Laurie A. Silva, Nicholas A. May, Joshua A. Bauer, Thomas E. Morrison, Terence S. Dermody
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
ABSTRACT Chikungunya virus (CHIKV) is a reemerging alphavirus that has caused epidemics of fever, arthralgia, and rash worldwide. There are currently no licensed vaccines or antiviral therapies available for the prevention or treatment of CHIKV disea
Externí odkaz:
https://doaj.org/article/14d88177dc7140fe8068a099bec59762
Autor:
Thomas E. Morrison, Stephanie A. Montgomery, Anthony J. Lentscher, Nicholas A May, Laurie A. Silva, Mary K. McCarthy, Bennett Davenport, Nicole McAllister, Terence S. Dermody, Krishnan Raghunathan
Publikováno v:
Journal of Clinical Investigation. 130:1466-1478
Chikungunya virus (CHIKV) is an arbovirus capable of causing a severe and often debilitating rheumatic syndrome in humans. CHIKV replicates in a wide variety of cell types in mammals, which has made attributing pathologic outcomes to replication at s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::736ec3eb079375cbd139ab194762c695
https://doi.org/10.1172/jci129893
https://doi.org/10.1172/jci129893
Autor:
Erin D. Lucas, Nicholas A May, Frances S. Li, Beth A. Jirón Tamburini, Cormac J. Lucas, Thomas E. Morrison, Mary K. McCarthy, Ryan M. Sheridan, Jay R. Hesselberth, Kathryn S. Carpentier, Glennys V. Reynoso, Bennett Davenport, Heather D. Hickman
Publikováno v:
The EMBO Journal. 40
Viremia in the vertebrate host is a major determinant of arboviral reservoir competency, transmission efficiency, and disease severity. However, immune mechanisms that control arboviral viremia are poorly defined. Here, we identify critical roles for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da95a3e599635df7cdaf7e305723c819
https://doi.org/10.15252/embj.2021108966
https://doi.org/10.15252/embj.2021108966
Autor:
Kathryn S, Carpentier, Ryan M, Sheridan, Cormac J, Lucas, Bennett J, Davenport, Frances S, Li, Erin D, Lucas, Mary K, McCarthy, Glennys V, Reynoso, Nicholas A, May, Beth A J, Tamburini, Jay R, Hesselberth, Heather D, Hickman, Thomas E, Morrison
Publikováno v:
EMBO J
Viremia in the vertebrate host is a major determinant of arboviral reservoir competency, transmission efficiency, and disease severity. However, immune mechanisms that control arboviral viremia are poorly defined. Here, we identify critical roles for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb02a6b0af49663d98739bf55eebc7ad
https://pubmed.ncbi.nlm.nih.gov/34618370
https://pubmed.ncbi.nlm.nih.gov/34618370
Autor:
Nathaniel J. Moorman, Nikhil Madadi, Daniel N. Streblow, Nicole N. Haese, Robert Bostwick, Mark T. Heise, Wes Sanders, Theresa H Nguyen, Corinne E. Augelli-Szafran, Nichole A Towers, Omar Moukha-Chafiq, Victor R. DeFilippis, Joseph A. Maddry, Sixue Zhang, Ashish K. Pathak, Mark J. Suto, Subramaniam Ananthan, Sharon Taft-Benz, Lynn Rasmussen, Shuklendu D Karyakarte, Michael Denton, Nicholas A May, Kevin J Rodzinak, Aaron D Streblow, Thomas E. Morrison
Publikováno v:
Antimicrob Agents Chemother
Venezuelan equine encephalitis virus (VEEV) is a reemerging alphavirus that can cause encephalitis resulting in severe human morbidity and mortality. Using a high-throughput cell-based screen, we identified a quinolinone compound that protected again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19d1e226b321e833dfc136126ea7547
https://pubmed.ncbi.nlm.nih.gov/34152810
https://pubmed.ncbi.nlm.nih.gov/34152810