Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nicholas A, Butowski"'
Autor:
Jacob S. Young, Reilly L. Kidwell, Allison Zheng, Alex F. Haddad, Manish K. Aghi, David R. Raleigh, Jessica D. Schulte, Nicholas A. Butowski
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Meningiomas are the most common non-metastatic brain tumors, and although the majority are relatively slow-growing and histologically benign, a subset of meningiomas are aggressive and remain challenging to treat. Despite a standard of care that incl
Externí odkaz:
https://doaj.org/article/ce5f3dc4eefb4fa8ab0de859a96b0799
Autor:
Hirokazu Ogino, Jennie W. Taylor, Takahide Nejo, David Gibson, Payal B. Watchmaker, Kaori Okada, Atsuro Saijo, Meghan R. Tedesco, Anny Shai, Cynthia M. Wong, Jane E. Rabbitt, Michael R. Olin, Christopher L. Moertel, Yasuhiko Nishioka, Andres M. Salazar, Annette M. Molinaro, Joanna J. Phillips, Nicholas A. Butowski, Jennifer L. Clarke, Nancy Ann Oberheim Bush, Shawn L. Hervey-Jumper, Philip Theodosopoulos, Susan M. Chang, Mitchel S. Berger, Hideho Okada
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
BACKGROUND Long-term prognosis of WHO grade II low-grade gliomas (LGGs) is poor, with a high risk of recurrence and malignant transformation into high-grade gliomas. Given the relatively intact immune system of patients with LGGs and the slow tumor g
Externí odkaz:
https://doaj.org/article/72c711424cf7433fa282c759cc09bb73
Autor:
Calixto-Hope G. Lucas, Emily A. Sloan, Rohit Gupta, Jasper Wu, Drew Pratt, Harish N. Vasudevan, Ajay Ravindranathan, Jairo Barreto, Erik A. Williams, Anny Shai, Nicholas S. Whipple, Carol S. Bruggers, Ossama Maher, Burt Nabors, Michael Rodriguez, David Samuel, Melandee Brown, Jason Carmichael, Rufei Lu, Kanish Mirchia, Daniel V. Sullivan, Melike Pekmezci, Tarik Tihan, Andrew W. Bollen, Arie Perry, Anuradha Banerjee, Sabine Mueller, Nalin Gupta, Shawn L. Hervey-Jumper, Nancy Ann Oberheim Bush, Mariza Daras, Jennie W. Taylor, Nicholas A. Butowski, John de Groot, Jennifer L. Clarke, David R. Raleigh, Joseph F. Costello, Joanna J. Phillips, Alyssa T. Reddy, Susan M. Chang, Mitchel S. Berger, David A. Solomon
Publikováno v:
Acta Neuropathologica. 144:747-765
Gliomas arising in the setting of neurofibromatosis type 1 (NF1) are heterogeneous, occurring from childhood through adulthood, can be histologically low-grade or high-grade, and follow an indolent or aggressive clinical course. Comprehensive profili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9443b332541d26f7f773096d51b660
https://doi.org/10.1007/s00401-022-02478-5
https://doi.org/10.1007/s00401-022-02478-5
Autor:
Patrick Roth, Susan Moran, Ge Wei, Francesca Avogadri, Cindy Xu, Steven Rowsey, Harris S. Soifer, Pierre Giglio, Cristóbal Belda-Iniesta, Morris D. Groves, Paul M.J. Clement, Nicholas A. Butowski, Patrick Y. Wen, Filip Y.F. De Vos, Jeffrey J. Raizer, Vinay K. Puduvalli, Miguel J. Gil-Gil, Timothy F. Cloughesy, Juan Manuel Sepúlveda-Sánchez, Andrew B. Lassman
Supplementary Table from Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e62bc045083f295b5505a4d2ceb22bf
https://doi.org/10.1158/1078-0432.22483670.v1
https://doi.org/10.1158/1078-0432.22483670.v1
Autor:
Michael D. Prados, David W. Craig, John D. Carpten, Michael E. Berens, Jeffrey M. Trent, Winnie S. Liang, Sara Nasser, Sen Peng, Gerald M. Maggiora, Annette M. Molinaro, Mitchel S. Berger, Susan M. Chang, Jennifer L. Clarke, Jennie W. Taylor, Nicholas A. Butowski, Ingo K. Mellinghoff, Timothy F. Cloughesy, Patrick Y. Wen, Keith L. Ligon, Howard Colman, John F. de Groot, John G. Kuhn, Joanna J. Phillips, Rebecca F. Halperin, Nhan L. Tran, Sara A. Byron
Study Workflow Diagram. Key steps in the study are outlined, including the number of patients at each stage. BEV: bevacizumab.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda8dbd25cdfe81cd1161fd83f3186ed
https://doi.org/10.1158/1078-0432.22466372
https://doi.org/10.1158/1078-0432.22466372
Autor:
Patrick Roth, Susan Moran, Ge Wei, Francesca Avogadri, Cindy Xu, Steven Rowsey, Harris S. Soifer, Pierre Giglio, Cristóbal Belda-Iniesta, Morris D. Groves, Paul M.J. Clement, Nicholas A. Butowski, Patrick Y. Wen, Filip Y.F. De Vos, Jeffrey J. Raizer, Vinay K. Puduvalli, Miguel J. Gil-Gil, Timothy F. Cloughesy, Juan Manuel Sepúlveda-Sánchez, Andrew B. Lassman
Purpose:FGFR genomic alterations (amplification, mutations, and/or fusions) occur in ∼8% of gliomas, particularly FGFR1 and FGFR3. We conducted a multicenter open-label, single-arm, phase II study of a selective FGFR1–3 inhibitor, infigratinib (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4433b4500bfad782b57ee3a0f26473dc
https://doi.org/10.1158/1078-0432.c.6531203
https://doi.org/10.1158/1078-0432.c.6531203
Autor:
Patrick Roth, Susan Moran, Ge Wei, Francesca Avogadri, Cindy Xu, Steven Rowsey, Harris S. Soifer, Pierre Giglio, Cristóbal Belda-Iniesta, Morris D. Groves, Paul M.J. Clement, Nicholas A. Butowski, Patrick Y. Wen, Filip Y.F. De Vos, Jeffrey J. Raizer, Vinay K. Puduvalli, Miguel J. Gil-Gil, Timothy F. Cloughesy, Juan Manuel Sepúlveda-Sánchez, Andrew B. Lassman
Supplementary Figure from Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1563a5aa4a79c34480a823bb1d174a04
https://doi.org/10.1158/1078-0432.22483673
https://doi.org/10.1158/1078-0432.22483673
Autor:
Michael D. Prados, David W. Craig, John D. Carpten, Michael E. Berens, Jeffrey M. Trent, Winnie S. Liang, Sara Nasser, Sen Peng, Gerald M. Maggiora, Annette M. Molinaro, Mitchel S. Berger, Susan M. Chang, Jennifer L. Clarke, Jennie W. Taylor, Nicholas A. Butowski, Ingo K. Mellinghoff, Timothy F. Cloughesy, Patrick Y. Wen, Keith L. Ligon, Howard Colman, John F. de Groot, John G. Kuhn, Joanna J. Phillips, Rebecca F. Halperin, Nhan L. Tran, Sara A. Byron
Purpose: Glioblastoma is an aggressive and molecularly heterogeneous cancer with few effective treatment options. We hypothesized that next-generation sequencing can be used to guide treatment recommendations within a clinically acceptable time frame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d428228d409e48210b0352b02b3c1b2
https://doi.org/10.1158/1078-0432.c.6526301
https://doi.org/10.1158/1078-0432.c.6526301
Autor:
Andrew B. Lassman, Juan Manuel Sepúlveda-Sánchez, Timothy F. Cloughesy, Miguel J. Gil-Gil, Vinay K. Puduvalli, Jeffrey J. Raizer, Filip Y.F. De Vos, Patrick Y. Wen, Nicholas A. Butowski, Paul M.J. Clement, Morris D. Groves, Cristóbal Belda-Iniesta, Pierre Giglio, Harris S. Soifer, Steven Rowsey, Cindy Xu, Francesca Avogadri, Ge Wei, Susan Moran, Patrick Roth
Publikováno v:
Clin Cancer Res
Purpose: FGFR genomic alterations (amplification, mutations, and/or fusions) occur in ∼8% of gliomas, particularly FGFR1 and FGFR3. We conducted a multicenter open-label, single-arm, phase II study of a selective FGFR1–3 inhibitor, infigratinib (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1992e8a27b1403d69013c5615f19e6fc
https://www.zora.uzh.ch/id/eprint/230044/
https://www.zora.uzh.ch/id/eprint/230044/
Autor:
Yalan Zhang, Calixto-Hope G Lucas, Jacob S Young, Ramin A Morshed, Lucie McCoy, Nancy Ann Oberheim Bush, Jennie W Taylor, Mariza Daras, Nicholas A Butowski, Javier E Villanueva-Meyer, Soonmee Cha, Margaret Wrensch, John K Wiencke, Julieann C Lee, Melike Pekmezci, Joanna J Phillips, Arie Perry, Andrew W Bollen, Manish K Aghi, Philip Theodosopoulos, Edward F Chang, Shawn L Hervey-Jumper, Mitchel S Berger, Jennifer L Clarke, Susan M Chang, Annette M Molinaro, David A Solomon
Publikováno v:
Neuro-oncology, vol 24, iss 10
Background Genomic profiling studies of diffuse gliomas have led to new improved classification schemes that better predict patient outcomes compared to conventional histomorphology alone. One example is the recognition that patients with IDH-wildtyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaa701d8cc0c6c8d5ee6cfe30727d53
https://pubmed.ncbi.nlm.nih.gov/35395677
https://pubmed.ncbi.nlm.nih.gov/35395677