Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicholas Dunwoody"'
Publikováno v:
Powder Diffraction. 35:247-261
Ag3O was synthesized by jet-milling magnetron-sputtered Ag–Ag2O thin films. Heating the jet-milled powders in air and N2 from 40 to 148 °C at ambient pressure produced Ag3O-rich powders. The phase composition and unit-cell parameters of the jet-mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbe1e4e36ee178c4462d7cfb6d367098
https://doi.org/10.1017/s0885715620000561
https://doi.org/10.1017/s0885715620000561
Autor:
Lars-Kristofer N Peterson, Lauren A Igneri, Nitin Puri, Nicholas Dunwoody, Danielle Green, Jason L. Bartock
Publikováno v:
The Journal of antimicrobial chemotherapy. 76(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d211be108dabeba9ed18c5a1b510662
https://pubmed.ncbi.nlm.nih.gov/34263304
https://pubmed.ncbi.nlm.nih.gov/34263304
Autor:
Wu-Yan Zhang, Minsheng He, Chi-Li Chen, Zhijian Zhu, Philip John Hogan, Nicholas Dunwoody, Magnus Ronn, Olga Gilicky
Publikováno v:
Organic Process Research & Development. 21:377-386
Process research, development, and manufacture of TP-808 (1), a key intermediate for the discovery and manufacture of tetracycline analogues, is described. The process used for the preparation of 1 avoids chromatographic purifications and has been su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47609db48039900f2c880bd3b121566e
https://doi.org/10.1021/acs.oprd.7b00003
https://doi.org/10.1021/acs.oprd.7b00003
Autor:
John Niu, Yonghong Deng, Magnus Ronn, Zhijian Zhu, Philip C. Hogan, Chi-Li Chen, Diana K. Hunt, Minsheng He, Wu-Yan Zhang, Xiao-Yi Xiao, Cuixiang Sun, Christopher E. Katz, Nicholas Dunwoody
Publikováno v:
Organic Process Research & Development. 20:284-296
Process research and development of the fully synthetic broad spectrum tetracycline TP-2758, with a chiral pyrrolidine side chain at the C-8 position, is described. The process utilizes two key intermediates, 7 and 10, in a convergent approach that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::757978d468e88e7bf9bb08c427f0b222
https://doi.org/10.1021/acs.oprd.5b00404
https://doi.org/10.1021/acs.oprd.5b00404
Autor:
Philip C. Hogan, Olga Gilicky, Zhimin Wang, Magnus Ronn, Danny Lafrance, Chi-Li Chen, John Niu, Wu-Yan Zhang, Nicholas Dunwoody
Publikováno v:
Organic Process Research & Development. 19:1784-1795
A robust, cost-effective, and high yielding manufacturing process for enantiomerically enriched (S)-allylic amine 3, a key intermediate for fully synthetic tetracyclines have been developed. Two novel and scalable asymmetric vinylations resulting in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09646552ec175274a3463920d90aac93
https://doi.org/10.1021/acs.oprd.5b00274
https://doi.org/10.1021/acs.oprd.5b00274
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4601d989b1e4e343ebfa836a79ca66dc
https://doi.org/10.1016/j.dmpk.2020.04.035
https://doi.org/10.1016/j.dmpk.2020.04.035
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 75:a382-a382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43bdedf13b8ab5f20f0443201141284f
https://doi.org/10.1107/s0108767319096272
https://doi.org/10.1107/s0108767319096272
Autor:
Wu-Yan Zhang, Zhijian Zhu, Philip C. Hogan, Magnus Ronn, Chi-Li Chen, John Niu, Yonghong Deng, Christopher E. Katz, Roger B. Clark, Xiao-Yi Xiao, Diana K. Hunt, Cuixiang Sun, Minsheng He, Olga Gilicky, Nicholas Dunwoody
Publikováno v:
Organic Process Research & Development. 17:838-845
Process research and development of the first fully synthetic broad spectrum 7-fluorotetracycline in clinical development is described. The process utilizes two key intermediates in a convergent approach. The key transformation is a Michael–Dieckma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8adac5b66737a518fc9a0ca8b62dbae8
https://doi.org/10.1021/op4000219
https://doi.org/10.1021/op4000219
Publikováno v:
The Journal of organic chemistry. 82(2)
A convergent route to eravacycline (1) has been developed by employing Michael–Dieckmann cyclization between enone 3 and a fully built and protected left-hand piece (LHP, 2). After construction of the core eravacycline structure, a deprotection rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab77675cbb71ed6384ec1747478beb2
https://pubmed.ncbi.nlm.nih.gov/28002943
https://pubmed.ncbi.nlm.nih.gov/28002943
Publikováno v:
Nano Letters. 7:1406-1412
We report in this paper a facile approach for the formation and electrochemical characterization of silver-silver oxide core-shell nanoparticles (NPs). Thus, thermal treatment at temperatures between 200 and 360 degrees C of Ag NP, in the gas phase o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bcb1d122a4a5bc47b1b957559804be
https://doi.org/10.1021/nl070268p
https://doi.org/10.1021/nl070268p