Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Nicholas, Willumsen"'
Autor:
Marina Crespo-Bravo, Jeppe Thorlacius-Ussing, Neel I. Nissen, Rasmus S. Pedersen, Mogens K. Boisen, Maria Liljefors, Astrid Z. Johansen, Julia S. Johansen, Morten A. Karsdal, Nicholas Willumsen
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Collagens are the major components of the extracellular matrix (ECM) and are known to contribute to tumor progression and metastasis. There are 28 different types of collagens each with unique functions in maintaining tissue struc
Externí odkaz:
https://doaj.org/article/8e62a07ff1ff43e4a58ac916255a431b
Autor:
Jeppe Thorlacius‐Ussing, Søren Risom Kristensen, Morten Asser Karsdal, Nicholas Willumsen, Shona Pedersen
Publikováno v:
Thoracic Cancer, Vol 14, Iss 28, Pp 2830-2838 (2023)
Abstract Background Small cell lung cancer (SCLC) is highly aggressive with limited therapeutic options and a poor prognosis. Moreover, noninvasive biomarker tools for detecting disease and monitoring treatment response are lacking. To address this,
Externí odkaz:
https://doaj.org/article/a76de1139bc64b588585c8bfc03c6cc9
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/13b5d4fe5b2d4c6b844204543e300bbe
Autor:
Christina Jensen, Nicholas Willumsen, Morten A Karsdal, Freek R van’t Land, Casper HJ van Eijck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2a811731da8e42afadf49572139a97f2
Autor:
Marco Donia, Christina Jensen, Nicholas Willumsen, Inge Svane, Anders Kverneland, Morten A Karsdal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/25ba024bb97e4b2a972743b51576cc53
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
It has been known for decades that the tumor extracellular matrix (ECM) is dysfunctional leading to loss of tissue architecture and promotion of tumor growth. The altered ECM and tumor fibrogenesis leads to tissue stiffness that act as a physical bar
Externí odkaz:
https://doaj.org/article/f18f4fb63fd74d4aaf0dd5c1f40c603d
Autor:
Rasmus S. Pedersen, Jeppe Thorlacius-Ussing, Maria G. Raimondo, Lasse L. Langholm, Georg Schett, Andreas Ramming, Morten Karsdal, Nicholas Willumsen
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 545 (2024)
Fibroblast activation protein (FAP) is a known promoter of tumor development and is associated with poor clinical outcome for various cancer types. Being specifically expressed in pathological conditions including multiple types of fibrosis and cance
Externí odkaz:
https://doaj.org/article/7841d04d187d419a8e4496e730df5dba
Autor:
Neel I. Nissen, Astrid Z. Johansen, Inna M. Chen, Christina Jensen, Emilie A. Madsen, Carsten P. Hansen, Jeppe Thorlacius-Ussing, Morten Karsdal, Julia S. Johansen, Hadi M. H. Diab, Lars N. Jørgensen, Nicholas Willumsen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a pronounced fibrotic tumor microenvironment, which impairs treatment response. Type I and V collagens are responsible for the densely packed fibrils in the tumor fibrosis envi
Externí odkaz:
https://doaj.org/article/8f4be5d66b1d42658607a755ed58cc35
Autor:
Christina Jensen, Neel I. Nissen, Claus S. Von Arenstorff, Morten A. Karsdal, Nicholas Willumsen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-11 (2021)
Abstract Despite the overall clinical success of immune checkpoint inhibitors (ICIs) for treating patients with solid tumors, a large number of patients do not benefit from this approach. Consequently, there is a need for predictive biomarkers. The m
Externí odkaz:
https://doaj.org/article/4a90731714c645489f05bc2af58b49ca
Autor:
Ying L. Liu, Cecilie Liv Bager, Nicholas Willumsen, Divya Ramchandani, Naomi Kornhauser, Lu Ling, Marta Cobham, Eleni Andreopoulou, Tessa Cigler, Anne Moore, Dayle LaPolla, Veronica Fitzpatrick, Maureen Ward, J. David Warren, Claudia Fischbach, Vivek Mittal, Linda T. Vahdat
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Tetrathiomolybdate (TM) is a novel, copper-depleting compound associated with promising survival in a phase II study of patients with high-risk and triple-negative breast cancer. We sought to elucidate the mechanism of TM by exploring its ef
Externí odkaz:
https://doaj.org/article/37a653a1d4054f088c420dae713f918a