Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicholas, Keat"'
Autor:
Ashwin V. Venkataraman, Nicholas Keat, James F. Myers, Samuel Turton, Inge Mick, Roger N. Gunn, Eugenii A. Rabiner, Jan Passchier, Christine A. Parker, Robin J. Tyacke, David J. Nutt
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Background We measured whole body distribution of 11C-BU99008, a new PET biomarker for non-invasive identification of the imidazoline2 binding site. The purpose of this phase I study was to evaluate the biodistribution and radiation dosimetr
Externí odkaz:
https://doaj.org/article/0063b94551df472fbb9998d94ab821a5
Autor:
Christophe Plisson, Lisa Wells, Christine A. Parker, Mayca Onega, Sara Moz, Nicholas Keat, Christopher Coello, Pauline T. Lukey, Giovanni Vitulli, Joaquim Ramada-Magalhaes, Roger N. Gunn, Frederick J. Wilson, Sharon Ashworth, Robert J. Slack, Sac-Pham Tang, Gaia Rizzo, Jan Passchier
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
PurposeIntegrin αvβ6belongs to the RGD subset of the integrin family, and its expression levels are a prognostic and theranostic factor in some types of cancer and pulmonary fibrosis. This paper describes the GMP radiolabelling of the synthetic 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0df9d47daff9ba4eabf23c6dbb7f6ff
http://europepmc.org/articles/PMC7075836
http://europepmc.org/articles/PMC7075836
Autor:
Chris P. Barnes, Nicholas Keat, Suraiya Dubash, Kasia Kozlowski, Tara Barwick, Eric O. Aboagye, Mickael Huiban, Diana Brickute, Sam Hill, Laura M. Kenny, Louis Allott
Background Fatty acids derived de novo or taken up from the extracellular space are an essential source of nutrient for cell growth and proliferation. Radiopharmaceuticals including 11C-acetate, and 18F-FAC (2-18F-fluoroacetate), have previously been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa7eac2b71f4f36aaa14b642172a472
http://hdl.handle.net/10044/1/78000
http://hdl.handle.net/10044/1/78000
Autor:
Suraiya R, Dubash, Nicholas, Keat, Kasia, Kozlowski, Chris, Barnes, Louis, Allott, Diana, Brickute, Sam, Hill, Mickael, Huiban, Tara D, Barwick, Laura, Kenny, Eric O, Aboagye
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Background Fatty acids derived de novo or taken up from the extracellular space are an essential source of nutrient for cell growth and proliferation. Radiopharmaceuticals including 11C-acetate, and 18F-FAC (2-18F-fluoroacetate), have previously been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf1a70bf3891a3315070dabeb1efc64b
https://pubmed.ncbi.nlm.nih.gov/32123971
https://pubmed.ncbi.nlm.nih.gov/32123971
Autor:
Eugenii A. Rabiner, Robin J. Tyacke, Jan Passchier, Inge Mick, Roger N. Gunn, David J. Nutt, Ashwin V. Venkataraman, Nicholas Keat, Jim Myers, Christine A. Parker, Samuel Turton
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-7 (2018)
Background We measured whole body distribution of 11C-BU99008, a new PET biomarker for non-invasive identification of the imidazoline2 binding site. The purpose of this phase I study was to evaluate the biodistribution and radiation dosimetry of 11C-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16c2cc5f2ee31e0e15fd328a115ee68
http://link.springer.com/article/10.1186/s13550-018-0429-x
http://link.springer.com/article/10.1186/s13550-018-0429-x
Autor:
R. Thomas Lumbers, Pauline T. Lukey, Jan Passchier, Nadia Garman, Nicholas Keat, Robert J. Slack, Mayca Onega, Azeem Saleem, Keguan Chen, Julia Kenny, William A. Hallett, Christine A. Parker
Publikováno v:
Journal of Nuclear Medicine Technology. 46:136-143
The αvβ6 integrin is involved in the pathogenesis of cancer and fibrosis. A radiolabeled 20-amino-acid αvβ6-binding peptide, derived from the foot and mouth virus (NAVPNLRGDLQVLAQKVART [A20FMDV2]), has been developed to image αvβ6 levels precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9903027bfdcc0fba4034daa56806736e
https://doi.org/10.2967/jnmt.117.203547
https://doi.org/10.2967/jnmt.117.203547
Autor:
Elise Emond, Michel Tohme, Ottavia Bertolli, Kristen A. Wangerin, Daniel Deidda, Kris Thielemans, William A. Hallett, Charalampos Tsoumpas, Floris Jansen, Gaspar Delso, Nikos Efthimiou, Palak Wadhwa, Timothy Deller, Roger N. Gunn, Nicholas Keat
Publikováno v:
Methods (San Diego, Calif.). 185
This work demonstrates how computational and physical modelling of the positron emission tomography (PET) image acquisition process for a state-of-the-art integrated PET and magnetic resonance imaging (PET-MR) system can produce images comparable to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86e977bbac9451d98edf7a0441e0296
https://pubmed.ncbi.nlm.nih.gov/32006678
https://pubmed.ncbi.nlm.nih.gov/32006678
Clinical Translation of a Click-Labeled 18F-Octreotate Radioligand for Imaging Neuroendocrine Tumors
Autor:
Rohini Sharma, Eric O. Aboagye, Andrea Frilling, Nicholas Keat, Azeem Saleem, Frazer J. Twyman, Kasia Kozlowski, Adil Al-Nahhas, Mickael Huiban, Laurence Carroll, Paola Mapelli, Ryan Janisch, Suraiya Dubash
Publikováno v:
Journal of Nuclear Medicine. 57:1207-1213
We conducted the first-in-human study of (18)F-fluoroethyl triazole [Tyr(3)] octreotate ((18)F-FET-βAG-TOCA) in patients with neuroendocrine tumors (NETs) to evaluate biodistribution, dosimetry, and safety. Despite advances in clinical imaging, dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1061d34e47922f28bb1d21aa367bb47
https://doi.org/10.2967/jnumed.115.169532
https://doi.org/10.2967/jnumed.115.169532
Autor:
Nicholas, Keat, Julia, Kenny, Keguan, Chen, Mayca, Onega, Nadia, Garman, Robert J, Slack, Christine A, Parker, R Thomas, Lumbers, Will, Hallett, Azeem, Saleem, Jan, Passchier, Pauline T, Lukey
Publikováno v:
Journal of nuclear medicine technology. 46(2)
The α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26a4211318ac1e28edc478046a0d8960
https://pubmed.ncbi.nlm.nih.gov/29438002
https://pubmed.ncbi.nlm.nih.gov/29438002
Autor:
Nicholas Keat, Julia F. Barrett
Publikováno v:
RadioGraphics. 24:1679-1691
Artifacts can seriously degrade the quality of computed tomographic (CT) images, sometimes to the point of making them diagnostically unusable. To optimize image quality, it is necessary to understand why artifacts occur and how they can be prevented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eccbbf3265ac23da3614f1b33427347
https://doi.org/10.1148/rg.246045065
https://doi.org/10.1148/rg.246045065