Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nichola C Garbett"'
Autor:
Shesh N Rai, Sudhir Srivastava, Jianmin Pan, Xiaoyong Wu, Somesh P Rai, Chongkham S Mekmaysy, Lynn DeLeeuw, Jonathan B Chaires, Nichola C Garbett
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220765 (2019)
The thermoanalytical technique differential scanning calorimetry (DSC) has been applied to characterize protein denaturation patterns (thermograms) in blood plasma samples and relate these to a subject's health status. The analysis and classification
Externí odkaz:
https://doaj.org/article/9437ad295cf94d8faceac981575995d2
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186232 (2017)
DSC is used to determine thermally-induced conformational changes of biomolecules within a blood plasma sample. Recent research has indicated that DSC curves (or thermograms) may have different characteristics based on disease status and, thus, may b
Externí odkaz:
https://doaj.org/article/4cd7c861f01f4381b98f30d3dfd22859
Autor:
Nichola C Garbett, Guy N Brock, Jonathan B Chaires, Chongkham S Mekmaysy, Lynn DeLeeuw, Kathy L Sivils, John B Harley, Brad H Rovin, K B Kulasekera, Wael N Jarjour
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186398 (2017)
OBJECTIVE:Plasma thermograms (thermal stability profiles of blood plasma) are being utilized as a new diagnostic approach for clinical assessment. In this study, we investigated the ability of plasma thermograms to classify systemic lupus erythematos
Externí odkaz:
https://doaj.org/article/512a96db786e4dc7a14a6eedc10242d1
Autor:
Nichola C Garbett, Michael L Merchant, C William Helm, Alfred B Jenson, Jon B Klein, Jonathan B Chaires
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84710 (2014)
Improved methods for the accurate identification of both the presence and severity of cervical intraepithelial neoplasia (CIN) and extent of spread of invasive carcinomas of the cervix (IC) are needed. Differential scanning calorimetry (DSC) has rece
Externí odkaz:
https://doaj.org/article/09cf011b9a9d40928773b730e7dea6fe
Autor:
Karita C. F. Lidani, Robert Buscaglia, Patrick J. Trainor, Shubham Tomar, Alagammai Kaliappan, Andrew P. DeFilippis, Nichola C. Garbett
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Background and aimsWith the advent and implementation of high-sensitivity cardiac troponin assays, differentiation of patients with distinct types of myocardial injuries, including acute thrombotic myocardial infarction (TMI), acute non-thrombotic my
Externí odkaz:
https://doaj.org/article/a4f24f91166a49c995fc601553fea834
Publikováno v:
Protein & Peptide Letters. 29:485-495
Background: The analysis of biofluid samples with low protein content (e.g., urine or saliva) can be challenging for downstream analysis methods with limited sensitivity. To circumvent this problem, sample processing methods are employed to increase
Autor:
Lee D. Hansen, Nichola C. Garbett, W. K. Dindi Chan, Alagammai Kaliappan, Benjamin Hicks, Jason Kenealey
Publikováno v:
ACS Food Science & Technology. 1:60-65
Invertase catalyzes the hydrolysis of sucrose to glucose and fructose. Invertase from Saccharomyces cerevisiae has been used in studies of the enzyme catalytic mechanism for more than a century. Is...
Autor:
Daniel W. Wilkey, J. Christopher States, Michael L. Merchant, Ageliki Lykoudi, Walter H. Watson, Jianmin Pan, Mayukh Banerjee, Shesh N. Rai, Nichola C. Garbett, Ana Paula Ferragut Cardoso
Publikováno v:
Chem Res Toxicol
Exposure to arsenic, a class I carcinogen, affects 200 million people globally. Skin is the major target organ, but the molecular etiology of arsenic-induced skin carcinogenesis remains unclear. Arsenite (As3+)-induced disruption of alternative splic
Autor:
Robert Buscaglia, Guy Brock, Gabriela Schneider, Nichola C. Garbett, Goetz H. Kloecker, Daniel W. Wilkey, Tanya Wiese, Alagammai Kaliappan, Michael L. Merchant, Jon B. Klein, Hiram Rivas-Perez, Taylor Q. Nguyen, Melissa Barousse Hall, Crissie DeSpirito
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5326, p 5326 (2021)
Volume 13
Issue 21
Cancers, Vol 13, Iss 5326, p 5326 (2021)
Volume 13
Issue 21
Simple Summary Lung cancer (LC) is the most common malignancy and the leading cause of cancer deaths in the world. Limitations of current screening approaches, such as substantial cost, radiation exposure, and high-false positive rates as well as inc
Autor:
Christine E. Schaner Tooley, Alan Cheng, Michael L. Merchant, Nichola C. Garbett, Kaitlyn M. Shields, Daniel W. Wilkey, Janusz J. Petkowski, John G. Tooley
Publikováno v:
Protein Science. 26:1639-1652
A subset of B-cell lymphoma patients have dominant mutations in the histone H3 lysine 27 (H3K27) methyltransferase EZH2, which change it from a monomethylase to a trimethylase. These mutations occur in aromatic resides surrounding the active site and