Výsledky vyhledávání - "Nichol Dolby"

Design and Expression of a Synthetic Mucin Gene Fragment inEscherichia Coli

Autor: Stephen E. Wright, Nichol Dolby, Kenneth E. Dombrowski

Publikováno v: Protein Expression and Purification. 15:146-154

Adenocarcinomas of glandular tissues produce a hypoglycosylated form of a normal glycoprotein (mucin) that elicits an immune response. A tumor-specific epitope of mucin occurs in a 20-amino-acid, tandemly repeated domain of human MUC1 mucin. A synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde0a906f9e75af03e56c8b87961396f
https://doi.org/10.1006/prep.1998.1002

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Context of MUC1 epitope: immunogenicity

Autor: J. S. Burnside, C. A. Phillips, I. S. Quinlin, K. E. Dombrowski, Nichol Dolby, S. E. Wright

Publikováno v: Oncology reports. 17(2)

MUC1 is a glycoprotein found at the secretory poles of normal cells but is hypoglycosylated on the entire surface of cell membranes of adenocarcinomas. In order to determine the influence on the immune response of peptide context for epitope presenta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca61e14ac30705927624d3b451887d4
https://pubmed.ncbi.nlm.nih.gov/17203187

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Cytotoxic T lymphocytes from humans with adenocarcinomas stimulated by native MUC1 mucin and a mucin peptide mutated at a glycosylation site

Autor: Nichol Dolby, Ji Yuan Wu, Ramila Philip, Karen E. Lowe, Lydia Kilinski, Stephen E. Wright, Sohel Talib, Jane S. Lebkowski, Janet S. Burnside, Kenneth E. Dombrowski

Publikováno v: Journal of immunotherapy (Hagerstown, Md. : 1997). 23(1)

MUC1 mucin peptides stimulated cytotoxic T lymphocytes (CTL) from humans with adenocarcinomas. Peripheral blood mononuclear cells, tumor-draining lymph node cells, or tumor-infiltrating lymphocytes were stimulated using mono-nuclear cells from humans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dddf312c2a309768759a13eb001b54
https://pubmed.ncbi.nlm.nih.gov/10687132

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Regulation of expression of TL genes of the mouse Mhc

Autor: Richard G. Cook, Nichol Dolby, Vidya Mehta

Publikováno v: Immunogenetics. 32

The expression of thymus leukemia (TL) antigens and genes in thymocytes and activated T cells was examined by immunoprecipitation, flow cytometric, northern, and nuclear run-off transcription analyses. Cell surface forms of TL were detectable by immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e71f9808a1e70631a685ffda7c90655
https://doi.org/10.1007/bf00241631

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