Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Nica, Borgese"'
Autor:
Nica Borgese, Andrés Guillén-Samander, Sara Francesca Colombo, Giulia Mancassola, Federica Di Berardino, Diego Zanetti, Paola Carrera
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2657 (2023)
Sensorineural age-related hearing loss affects a large proportion of the elderly population, and has both environmental and genetic causes. Notwithstanding increasing interest in this debilitating condition, the genetic risk factors remain largely un
Externí odkaz:
https://doaj.org/article/206639dbb97c4208bef9c25b323f0551
Autor:
Ersilia Varone, Alexander Chernorudskiy, Alessandro Cherubini, Angela Cattaneo, Angela Bachi, Stefano Fumagalli, Gizem Erol, Marco Gobbi, Michael J. Lenardo, Nica Borgese, Ester Zito
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102455- (2022)
N-glycosylation and disulfide bond formation are two essential steps in protein folding that occur in the endoplasmic reticulum (ER) and reciprocally influence each other. Here, to analyze crosstalk between N-glycosylation and oxidation, we investiga
Externí odkaz:
https://doaj.org/article/d175f4e69c8544f7a0d915547de36689
Publikováno v:
Contact, Vol 4 (2021)
Nearly twenty years ago a mutation in the VAPB gene, resulting in a proline to serine substitution (p.P56S), was identified as the cause of a rare, slowly progressing, familial form of the motor neuron degenerative disease Amyotrophic Lateral Scleros
Externí odkaz:
https://doaj.org/article/e6ab3001af5f4618909d3e3b99ea4ea8
Publikováno v:
Cells, Vol 10, Iss 8, p 1865 (2021)
The VAP proteins are integral adaptor proteins of the endoplasmic reticulum (ER) membrane that recruit a myriad of interacting partners to the ER surface. Through these interactions, the VAPs mediate a large number of processes, notably the generatio
Externí odkaz:
https://doaj.org/article/9d5827b0ab894b6b83f692127750f5f2
Publikováno v:
Cells, Vol 4, Iss 3, Pp 354-386 (2015)
Autophagy plays a major role in the elimination of cellular waste components, the renewal of intracellular proteins and the prevention of the build-up of redundant or defective material. It is fundamental for the maintenance of homeostasis and especi
Externí odkaz:
https://doaj.org/article/24245208839f472ab723e93e7542e516
Autor:
Ersilia Varone, Alexander Chernorudisky, Alessandro Cherubini, Alessandra Decio, Nica Borgese, Raffella Giavazzi, Ester Zito
Publikováno v:
Free Radical Biology and Medicine. 201:5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3103a3b625d2f8927e58a7cca9def393
https://doi.org/10.1016/j.freeradbiomed.2023.03.044
https://doi.org/10.1016/j.freeradbiomed.2023.03.044
Autor:
Nica Borgese
Publikováno v:
Traffic. 21:647-658
The tryptophan rich basic protein/calcium signal-modulating cyclophilin ligand (WRB/CAML) and Get1p/Get2p complexes, in vertebrates and yeast, respectively, mediate the final step of tail-anchored protein insertion into the endoplasmic reticulum memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0302bc545176e10ab5124f75aa83e6f9
https://doi.org/10.1111/tra.12758
https://doi.org/10.1111/tra.12758
Autor:
Ersilia Varone, Giovanna Musco, Stefano Fumagalli, Andrea Berardi, Nica Borgese, Sara Francesca Colombo, Angela Cattaneo, Mickaël Briens, Mario Salmona, Alfredo Cagnotto, Angela Bachi, Ester Zito, Alain Lescure, Mireille Baltzinger, Lauriane Kuhn, Alexander Chernorudskiy
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Selenoprotein N (SEPN1) is a type II transmembrane protein of the endoplasmic reticulum (ER) that senses luminal calcium through an EF-hand domain. On calcium depletion, a SEPN1 oligomer, prevalent under basal calcium concentrations, dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef850864cbf3e9362e601ffb32f146b6
http://europepmc.org/articles/PMC7474598
http://europepmc.org/articles/PMC7474598
Publikováno v:
Cells
Cells, Vol 10, Iss 1865, p 1865 (2021)
Cells, Vol 10, Iss 1865, p 1865 (2021)
The VAP proteins are integral adaptor proteins of the endoplasmic reticulum (ER) membrane that recruit a myriad of interacting partners to the ER surface. Through these interactions, the VAPs mediate a large number of processes, notably the generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83aa805f1ab8ec09bdb0539d2afe6276
http://europepmc.org/articles/PMC8392409
http://europepmc.org/articles/PMC8392409
Autor:
Paola Genevini, Giulia Papiani, Annamaria Ruggiano, Lavinia Cantoni, Francesca Navone, Nica Borgese
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113416 (2014)
VAPB is a ubiquitously expressed, ER-resident adaptor protein involved in interorganellar lipid exchange, membrane contact site formation, and membrane trafficking. Its mutant form, P56S-VAPB, which has been linked to a dominantly inherited form of A
Externí odkaz:
https://doaj.org/article/75c43c67efce43eabfa28948fad5b11f