Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Niat T. Gebru"'
Autor:
Marangelie Criado-Marrero, Danielle M. Blazier, Lauren A. Gould, Niat T. Gebru, Santiago Rodriguez Ospina, Debra S. Armendariz, April L. Darling, David Beaulieu-Abdelahad, Laura J. Blair
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Tau accumulation and progressive loss of neurons are associated with Alzheimer’s disease (AD). Aggregation of tau has been associated with endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). While E
Externí odkaz:
https://doaj.org/article/64dff707852e4d75bac6a3dfb818855a
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Lauren A. Gould, Danielle M. Blazier, Yamile Vidal-Aguiar, Taylor M. Smith, Salma S. Abdelmaboud, Lindsey B. Shelton, Xinming Wang, Jan Dahrendorff, David Beaulieu-Abdelahad, Chad A. Dickey, Laura J. Blair
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Abnormal accumulation of hyperphosphorylated tau induces pathogenesis in neurodegenerative diseases, like Alzheimer’s disease. Molecular chaperones with peptidyl-prolyl cis/trans isomerase (PPIase) activity are known to regulate these proc
Externí odkaz:
https://doaj.org/article/b06d2c045077424ca482d80168b5726e
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu-Abdelahad, Laura J. Blair
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract The microtubule associated protein tau is an intrinsically disordered phosphoprotein that accumulates under pathological conditions leading to formation of neurofibrillary tangles, a hallmark of Alzheimer’s disease (AD). The mechanisms tha
Externí odkaz:
https://doaj.org/article/96db6774e5134960a85eb9d69ac1073a
Autor:
Santiago Rodriguez Ospina, Danielle M. Blazier, Marangelie Criado-Marrero, Lauren A. Gould, Niat T. Gebru, David Beaulieu-Abdelahad, Xinming Wang, Elizabeth Remily-Wood, Dale Chaput, Stanley Stevens, Vladimir N. Uversky, Paula C. Bickford, Chad A. Dickey, Laura J. Blair
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 851 (2022)
The microtubule-associated protein tau pathologically accumulates and aggregates in Alzheimer’s disease (AD) and other tauopathies, leading to cognitive dysfunction and neuronal loss. Molecular chaperones, like small heat-shock proteins (sHsps), ca
Externí odkaz:
https://doaj.org/article/2ece1a9b1c4a46c8bd5a5ee4da623119
Correction to: Hsp90 co‑chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild‑type mice
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu-Abdelahad, Laura J. Blair
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/46ce15823dae4f4db34d871dcda27a46
Publikováno v:
Journal of Cellular Biochemistry.
Autor:
Danielle M. Blazier, Laura J. Blair, David Beaulieu-Abdelahad, Yamile Vidal-Aguiar, Xinming Wang, Chad A. Dickey, Marangelie Criado-Marrero, Taylor M. Smith, Lauren A. Gould, Salma S. Abdelmaboud, Lindsey B. Shelton, Jan Dahrendorff, Niat T. Gebru
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-13 (2021)
NPJ Aging and Mechanisms of Disease
NPJ Aging and Mechanisms of Disease
Abnormal accumulation of hyperphosphorylated tau induces pathogenesis in neurodegenerative diseases, like Alzheimer’s disease. Molecular chaperones with peptidyl-prolyl cis/trans isomerase (PPIase) activity are known to regulate these processes. Pr
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Lauren A. Gould, Taylor M. Smith, Sojeong Kim, Roy J. Blackburn, Chad A. Dickey, Laura J. Blair
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2738 (2019)
Clinical studies show a significant association of childhood adversities and FK506-binding protein 5 (FKBP5) polymorphisms on increasing the susceptibility for neuropsychiatric disorders. However, the mechanisms by which early life stress (ELS) influ
Externí odkaz:
https://doaj.org/article/0e5905a28ea6441e81965f7a6648f097
Autor:
Marangelie, Criado-Marrero, Danielle M, Blazier, Lauren A, Gould, Niat T, Gebru, Santiago, Rodriguez Ospina, Debra S, Armendariz, April L, Darling, David, Beaulieu-Abdelahad, Laura J, Blair
Publikováno v:
Scientific reports. 12(1)
Tau accumulation and progressive loss of neurons are associated with Alzheimer's disease (AD). Aggregation of tau has been associated with endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). While ER stress an
Autor:
Jeremy D. Baker, David Beaulieu-Abdelahad, Laura J. Blair, Danielle M. Blazier, Lauren A. Gould, Marangelie Criado-Marrero, Niat T. Gebru
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
The microtubule associated protein tau is an intrinsically disordered phosphoprotein that accumulates under pathological conditions leading to formation of neurofibrillary tangles, a hallmark of Alzheimer’s disease (AD). The mechanisms that initiat