Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Niarakis, A"'
Publikováno v:
Journal of Integrative Bioinformatics, Vol 21, Iss 1, Pp 1-13 (2024)
Molecular interaction maps (MIMs) are static graphical representations depicting complex biochemical networks that can be formalized using one of the Systems Biology Graphical Notation languages. Regardless of their extensive coverage of various biol
Externí odkaz:
https://doaj.org/article/205e0bb2232b4955ab2d07cad6f0a773
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Macrophages play an essential role in rheumatoid arthritis. Depending on their phenotype (M1 or M2), they can play a role in the initiation or resolution of inflammation. The M1/M2 ratio in rheumatoid arthritis is higher than in healthy cont
Externí odkaz:
https://doaj.org/article/6fa72883246148da88175b0484e04a7f
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Rheumatoid arthritis (RA) is a complex autoimmune disease with an unknown aetiology. However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in initiating and perpetuating destructive joint inflammation by
Externí odkaz:
https://doaj.org/article/16e6384c502c471c8019c745ede70929
Autor:
Anna Niarakis, Marek Ostaszewski, Alexander Mazein, Inna Kuperstein, Martina Kutmon, Marc E. Gillespie, Akira Funahashi, Marcio Luis Acencio, Ahmed Hemedan, Michael Aichem, Karsten Klein, Tobias Czauderna, Felicia Burtscher, Takahiro G. Yamada, Yusuke Hiki, Noriko F. Hiroi, Finterly Hu, Nhung Pham, Friederike Ehrhart, Egon L. Willighagen, Alberto Valdeolivas, Aurelien Dugourd, Francesco Messina, Marina Esteban-Medina, Maria Peña-Chilet, Kinza Rian, Sylvain Soliman, Sara Sadat Aghamiri, Bhanwar Lal Puniya, Aurélien Naldi, Tomáš Helikar, Vidisha Singh, Marco Fariñas Fernández, Viviam Bermudez, Eirini Tsirvouli, Arnau Montagud, Vincent Noël, Miguel Ponce-de-Leon, Dieter Maier, Angela Bauch, Benjamin M. Gyori, John A. Bachman, Augustin Luna, Janet Piñero, Laura I. Furlong, Irina Balaur, Adrien Rougny, Yohan Jarosz, Rupert W. Overall, Robert Phair, Livia Perfetto, Lisa Matthews, Devasahayam Arokia Balaya Rex, Marija Orlic-Milacic, Luis Cristobal Monraz Gomez, Bertrand De Meulder, Jean Marie Ravel, Bijay Jassal, Venkata Satagopam, Guanming Wu, Martin Golebiewski, Piotr Gawron, Laurence Calzone, Jacques S. Beckmann, Chris T. Evelo, Peter D’Eustachio, Falk Schreiber, Julio Saez-Rodriguez, Joaquin Dopazo, Martin Kuiper, Alfonso Valencia, Olaf Wolkenhauer, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID-19 Disease Map Community
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionThe COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop interoperable b
Externí odkaz:
https://doaj.org/article/ac53015acf3143cf9c3f232ae67ad161
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4196-4206 (2023)
Cancer-associated fibroblasts (CAFs) are amongst the key players of the tumor microenvironment (TME) and are involved in cancer initiation, progression, and resistance to therapy. They exhibit aggressive phenotypes affecting extracellular matrix remo
Externí odkaz:
https://doaj.org/article/7499f8055fe24f6299162c3b3dce8de4
Publikováno v:
In Computational and Structural Biotechnology Journal 2023 21:4196-4206
Autor:
Alexander Mazein, Marcio Luis Acencio, Irina Balaur, Adrien Rougny, Danielle Welter, Anna Niarakis, Diana Ramirez Ardila, Ugur Dogrusoz, Piotr Gawron, Venkata Satagopam, Wei Gu, Andreas Kremer, Reinhard Schneider, Marek Ostaszewski
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
As a conceptual model of disease mechanisms, a disease map integrates available knowledge and is applied for data interpretation, predictions and hypothesis generation. It is possible to model disease mechanisms on different levels of granularity and
Externí odkaz:
https://doaj.org/article/f0f445384bda413f8afbd1d17acb3009
Autor:
Paul Soudier, Daniel Rodriguez Pinzon, Tristan Reif-Trauttmansdorff, Hassan Hijazi, Maëva Cherrière, Cátia Goncalves Pereira, Doriane Blaise, Maxime Pispisa, Angelyne Saint-Julien, William Hamlet, Melissa Nguevo, Eva Gomes, Sophia Belkhelfa, Anna Niarakis, Manish Kushwaha, Ioana Grigoras
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 2, Pp 791-801 (2022)
Nucleic acid sensing is a 3 decades old but still challenging area of application for different biological sub-domains, from pathogen detection to single cell transcriptomics analysis. The many applications of nucleic acid detection and identificatio
Externí odkaz:
https://doaj.org/article/ea936bd387ad4d75b66170b91c58587a
Autor:
R. Laubenbacher, A. Niarakis, T. Helikar, G. An, B. Shapiro, R. S. Malik-Sheriff, T. J. Sego, A. Knapp, P. Macklin, J. A. Glazier
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-5 (2022)
Abstract Digital twins, customized simulation models pioneered in industry, are beginning to be deployed in medicine and healthcare, with some major successes, for instance in cardiovascular diagnostics and in insulin pump control. Personalized compu
Externí odkaz:
https://doaj.org/article/c549c9a9ea144d89bda0c789fa1dfa1d
Publikováno v:
In Computational and Structural Biotechnology Journal 2022 20:3161-3172