Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Nianyu Li"'
Autor:
Nianyu Li, Zhuqing Li, Fang Fang, Chendi Zhu, Wenzhe Zhang, Yueshuang Lu, Rongrong Zhang, Pinxin Si, Yuehong Bian, Yingying Qin, Xue Jiao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionTissue-resident macrophages (TRMs) are highly heterogeneous and have a complex and important role in tissue support, homeostasis, and function. The heterogeneity, maintenance, and function of TRMs, as one of the major immune cells in the
Externí odkaz:
https://doaj.org/article/42b4afab7c37487197ee4d69ed3d792d
Autor:
Lisa M. Plitnick, Beth Hutchins, Sheri Dubey, Nianyu Li, Rupesh P. Amin, Stephanie Born, Ruban Mangadu, Joseph H. Phillips, Venkataraman Sriram, Danuta J. Herzyk
Publikováno v:
Journal of Immunotoxicology, Vol 17, Iss 1, Pp 175-185 (2020)
The programmed cell death 1 (PD-1) pathway represents a major immune checkpoint which may be engaged by cells in a tumor microenvironment to overcome active T-cell immune surveillance. Pembrolizumab (Keytruda®) is a potent and highly selective human
Externí odkaz:
https://doaj.org/article/2b47def718a34f4fad7a7bc77b84c7e9
Autor:
Mark Collinge, Patricia Schneider, Dingzhou Li, Stanley Parish, Carolyne Dumont, Wendy Freebern, Joseph Ghanime, Fanny Guimont-Derochers, Anja Langenkamp, Jose Lebron, Nianyu Li, Celine Marban, Lisa Plitnick, Jennifer Wheeler
Publikováno v:
Journal of Immunotoxicology, Vol 17, Iss 1, Pp 51-58 (2020)
Nonclinical immunotoxicity evaluation is an important component of safety assessment for pharmaceuticals. One in vitro assay that can be applied in a weight of evidence assessment is the human lymphocyte activation (HuLA) assay, an antigen recall ass
Externí odkaz:
https://doaj.org/article/d778ca1e897a4b63b8c879d6165eca51
Publikováno v:
IEEE Access, Vol 8, Pp 200322-200337 (2020)
In cyber-physical systems, physical and software components are deeply intertwined, blurring the boundaries between the cyber and physical worlds. Perceiving environmental information is a prerequisite for a cyber-physical system to be reliable and a
Externí odkaz:
https://doaj.org/article/5dd6792462f5495a8d1d75d48b1d6973
Autor:
Xue Jiao, Xiruo Zhang, Nianyu Li, Dunfang Zhang, Shidou Zhao, Yujie Dang, Peter Zanvit, Wenwen Jin, Zi‐Jiang Chen, Wanjun Chen, Yingying Qin
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Abstract Immune dysregulation has long been proposed as a component of premature ovarian insufficiency (POI), but the underlying mediators and mechanisms remain largely unknown. Here we showed that patients with POI had augmented T helper 1 (TH1) res
Externí odkaz:
https://doaj.org/article/0ffe8d5c7b64440ca94a715dac1749e3
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Background. circRNAs are part of the competitive endogenous RNA network, which putatively function as miRNA sponges and play a crucial role in the development of numerous diseases. However, studies of circRNAs in rheumatoid arthritis (RA) disease are
Externí odkaz:
https://doaj.org/article/f36f1f66451448f8ad04d42ee0f7a79e
Autor:
Maria V Tsiper, Jennifer Sturgis, Larisa V Avramova, Shilpa Parakh, Raymond Fatig, Ana Juan-García, Nianyu Li, Bartek Rajwa, Padma Narayanan, C W Qualls, J Paul Robinson, V Jo Davisson
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45226 (2012)
Early evaluation of new drug entities for their potential to cause mitochondrial dysfunction is becoming an important task for drug development. Multi-parametric high-content screening (mp-HCS) of mitochondrial toxicity holds promise as a lead in-vit
Externí odkaz:
https://doaj.org/article/b6c68ecb6bc142c08773a57eec5a927a
Publikováno v:
ACM Transactions on Autonomous and Adaptive Systems. 17:1-26
Many self-adaptive systems benefit from human involvement and oversight, where a human operator can provide expertise not available to the system and detect problems that the system is unaware of. One way of achieving this synergy is by placing the h
Publikováno v:
Thyroid
BACKGROUND: Thyroid dysfunction is prevalent in reproductive-age women and has been identified as a risk factor for female infertility. However, it remains largely unclear whether subtle thyroid dysfunction, as estimated by moderately high thyrotropi
Autor:
Gregory L. Adams, Parul S. Pall, Steven M. Grauer, Xiaoping Zhou, Jeanine E. Ballard, Marissa Vavrek, Richard L. Kraus, Pierre Morissette, Nianyu Li, Stefania Colarusso, Elisabetta Bianchi, Anandan Palani, Rebecca Klein, Christopher T. John, Deping Wang, Matthew Tudor, Andrew F. Nolting, Mirlinda Biba, Timothy Nowak, Alexey A. Makarov, Mikhail Reibarkh, Alexei V. Buevich, Wendy Zhong, Erik L. Regalado, Xiao Wang, Qi Gao, Aurash Shahripour, Yuping Zhu, Daniele de Simone, Tommaso Frattarelli, Nicolo’ Maria Pasquini, Paola Magotti, Roberto Iaccarino, Yuxing Li, Kelli Solly, Keun-Joong Lee, Weixun Wang, Feifei Chen, Haoyu Zeng, Jixin Wang, Hilary Regan, Rupesh P. Amin, Christopher P. Regan, Christopher S. Burgey, Darrell A. Henze, Chengzao Sun, David M. Tellers
Publikováno v:
Journal of Medicinal Chemistry. 65:485-496