Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Nianqing Xiao"'
Autor:
Yunhe Ju, Xingrao Wu, Huizhen Wang, Bin Li, Qing Long, Dadong Zhang, Hao Chen, Nianqing Xiao, Fugen Li, Shiwen Zhang, Shenggang Yang
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
BackgroundThe characteristics of head and neck squamous cell carcinoma (HNSCC) across different anatomic sites in the Chinese population have not been studied. To determine the genomic abnormalities underlying HNSCC across different anatomic sites, t
Externí odkaz:
https://doaj.org/article/2066e96a619c4f5788f649404a20e9b9
Publikováno v:
Cancer Medicine, Vol 7, Iss 3, Pp 746-756 (2018)
Abstract Microsatellite instability (MSI) testing identifies patients who may benefit from immune checkpoint inhibitors. We developed an MSI assay that uses data from a commercially available next‐generation sequencing (NGS) panel to determine MSI
Externí odkaz:
https://doaj.org/article/507c6f8e76314105b442a5c0a9ac8a1b
Autor:
Valeriy Domenyuk, Zoran Gatalica, Radhika Santhanam, Xixi Wei, Adam Stark, Patrick Kennedy, Brandon Toussaint, Symon Levenberg, Jie Wang, Nianqing Xiao, Richard Greil, Gabriel Rinnerthaler, Simon P. Gampenrieder, Amy B. Heimberger, Donald A. Berry, Anna Barker, John Quackenbush, John L. Marshall, George Poste, Jeffrey L. Vacirca, Gregory A. Vidal, Lee S. Schwartzberg, David D. Halbert, Andreas Voss, Daniel Magee, Mark R. Miglarese, Michael Famulok, Günter Mayer, David Spetzler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Patients’ selection is particularly important in cancer treatment. Here the authors present a proof-of-principle methodology that could be potentially important in assisting therapeutic decisions in the treatment of breast cancer patients.
Externí odkaz:
https://doaj.org/article/5a4c54b8e9744dccbcb331d197302fe8
Autor:
Qing Long, Shenggang Yang, Fugen Li, Dadong Zhang, Nianqing Xiao, Xingrao Wu, Shiwen Zhang, Yunhe Ju, Hao Chen, Huizhen Wang, Bin Li
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
BackgroundThe characteristics of head and neck squamous cell carcinoma (HNSCC) across different anatomic sites in the Chinese population have not been studied. To determine the genomic abnormalities underlying HNSCC across different anatomic sites, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b13d5096ead07b9e7387ebae8e3c7a
https://www.frontiersin.org/articles/10.3389/fgene.2021.680699/full
https://www.frontiersin.org/articles/10.3389/fgene.2021.680699/full
Publikováno v:
Cancer Medicine
Microsatellite instability (MSI) testing identifies patients who may benefit from immune checkpoint inhibitors. We developed an MSI assay that uses data from a commercially available next‐generation sequencing (NGS) panel to determine MSI status. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d56bf35cb7f88c4118d700bc76fb80
https://doi.org/10.1002/cam4.1372
https://doi.org/10.1002/cam4.1372
Autor:
Wangjuh Chen, Semir Vranic, Rebecca Feldman, Sandeep K. Reddy, Juan P. Palazzo, Nianqing Xiao, Jeffrey Swensen, Upasana Joneja, Zoran Gatalica, Jeffrey Kimbrough
Publikováno v:
Journal of Clinical Pathology
Aims Metaplastic breast carcinoma (MBC) is a rare subtype of breast carcinoma less responsive to conventional chemotherapy than ductal carcinoma. In molecular terms, MBCs usually cluster with triple-negative breast cancers (TNBCs), but have a worse p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542e54b467a03fcd659cd5d943b92eca
http://europepmc.org/articles/PMC5339564
http://europepmc.org/articles/PMC5339564
Autor:
Sandeep K. Reddy, Jeffrey Swensen, Rebecca Feldman, Juan P. Palazzo, Wangjuh Sting Chen, Zoran Gatalica, U Joneja, Nianqing Xiao, Anatole Ghazalpour, F Cai
Publikováno v:
Cancer Research. 76:P3-07
Background: Metaplastic breast carcinoma (MBC) is a rare subtype of breast carcinoma less responsive to conventional chemotherapy relative to usual breast carcinomas (UBCs) such as ductal and lobular subtype. In molecular terms MBC usually clusters w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6123ef825425df764b330b98a8e2ba9
https://doi.org/10.1158/1538-7445.sabcs15-p3-07-47
https://doi.org/10.1158/1538-7445.sabcs15-p3-07-47
Autor:
Nickolas Papadopoulos, Nianqing Xiao, Robert A. Anders, Kristen K. Ciombor, Shibin Zhou, Katherine M. Bever, Cara Wilt, Bao H. Lam, Hao Wang, Janis M. Taube, George A. Fisher, Matthias Holdhoff, Fay Wong, Richard M. Goldberg, Amanda N. Fader, Ludmila Danilova, Jennifer N. Durham, Laveet K. Aulakh, David Spetzler, Leslie Cope, Dung T. Le, Christian F. Meyer, Franck Housseau, James J. Lee, Aleksandra Eyring, Andrew K. Joe, James R. Eshleman, Deborah K. Armstrong, Bjarne Bartlett, Kellie N. Smith, Brandon Luber, Agnieszka A. Rucki, Daniel A. Laheru, Steve Lu, Nilofer S. Azad, Todd S. Crocenzi, Kenneth W. Kinzler, Tim F. Greten, Austin G. Duffy, Bert Vogelstein, Drew M. Pardoll, Luis A. Diaz, Atif Zaheer, Holly Kemberling, S. Peter Kang, Ross C. Donehower
Predicting responses to immunotherapy Colon cancers with loss-of-function mutations in the mismatch repair (MMR) pathway have favorable responses to PD-1 blockade immunotherapy. In a phase 2 clinical trial, Le et al. showed that treatment success is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4527179e77e9a993495411588f44d3
https://europepmc.org/articles/PMC5576142/
https://europepmc.org/articles/PMC5576142/
Autor:
George Poste, Adam Stark, Valeriy Domenyuk, Janet E. Duncan, Joachim Schorr, David D. Halbert, Nianqing Xiao, Sonal S. Tonapi, Jie Wang, Heather A. O'Neill, John Quackenbush, Donald A. Berry, Teresa T. Tinder, Zhenyu Zhong, Andrew Hunter, Mark R. Miglarese, Xixi Wei, Tassilo Hornung, Günter Mayer, David Spetzler, Michael Famulok
Publikováno v:
Scientific Reports
Technologies capable of characterizing the full breadth of cellular systems need to be able to measure millions of proteins, isoforms, and complexes simultaneously. We describe an approach that fulfils this criterion: Adaptive Dynamic Artificial Poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b076c58e09baf5152b6d56d6510aea2
https://hdl.handle.net/11858/00-001M-0000-002C-F1E4-711858/00-001M-0000-002C-F1E6-3
https://hdl.handle.net/11858/00-001M-0000-002C-F1E4-711858/00-001M-0000-002C-F1E6-3
Autor:
Daniel D. Von Hoff, Omid Hamid, Peggy Overberg, Anatole Ghazalpour, Gargi D. Basu, Semir Vranic, Nianqing Xiao, Zoran Gatalica, Henry T. Lynch, Todd Maney, Inga Rose, Carrie Snyder, Daniel A. Holterman
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 23:2965-2970
Cancer cells expressing PD-1 ligands (PD-L1/PD-L2) inhibit immune-modulatory T-cell activation facilitating disease progression. Preliminary clinical trials exploring interruption of PD-1/PD-L1 signaling showed benefit in several cancer types. We ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e340053e3e94dda547b3ebccd76e90
https://doi.org/10.1158/1055-9965.epi-14-0654
https://doi.org/10.1158/1055-9965.epi-14-0654