The Hippo Transducer YAP/TAZ as a Biomarker of Therapeutic Response and Prognosis in Trastuzumab-Based Neoadjuvant Therapy Treated HER2-Positive Breast Cancer Patients

Autor: Jia-qi Yuan, Nian-hua Ding, Zhi Xiao

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

BackgroundWe explored the therapeutic and prognostic effect of YAP/TAZ intensityinHER2-positive breast cancer patients. We also investigated the relationship between YAP/TAZ expression and Trastuzumab-resistance.MethodsWe collected clinicopathologica

Externí odkaz: https://doaj.org/article/d3d8c4d6ebc146638b457f70d53b8f0d

Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis

Autor: Lun Quan Sun, Nian Hua Ding, Jian Jian Li

Publikováno v: Current Drug Targets
Current drug targets, vol 14, iss 11
Ding, NH; Li, JJ; & Sun, LQ. (2013). Molecular mechanisms and treatment of radiation-induced lung fibrosis. Current Drug Targets, 14(11), 1347-1356. doi: 10.2174/13894501113149990198. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/9v81v9hn

Radiation-induced lung fibrosis (RILF) is a severe side effect of radiotherapy in lung cancer patients that presents as a progressive pulmonary injury combined with chronic inflammation and exaggerated organ repair. RILF is a major barrier to improvi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c792fe29cc395bd068183328d7d3aad8
https://doi.org/10.2174/13894501113149990198