Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nian-Ling Zhu"'
Publikováno v:
Journal of Gastroenterology and Hepatology. 27:94-98
Hepatic stellate cells (HSC) are the liver mesenchymal cell type which responds to hepatocellular damage and participates in wound healing. Although HSC myofibroblastic trans-differentiation (activation) is implicated in excessive extracellular matri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16980d2491b79632c43a71b4c1ba18cc
https://doi.org/10.1111/j.1440-1746.2011.07022.x
https://doi.org/10.1111/j.1440-1746.2011.07022.x
Publikováno v:
Hepatology Research. 41:675-682
Research in the past three decades has identified key mediators and signaling mechanisms responsible for myofibroblastic transdifferentiation (MTD) of hepatic stellate cells (HSC), the pivotal event in liver fibrogenesis. Yet, fundamental understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc42fd276078210b6e8556f3c42c882b
https://doi.org/10.1111/j.1872-034x.2011.00804.x
https://doi.org/10.1111/j.1872-034x.2011.00804.x
Autor:
Changgong Li, Saverio Bellusci, John Groffen, Dimitris Kardassis, Parviz Minoo, Zea Borok, Nian-Ling Zhu, Lingyan Hu
Publikováno v:
Nucleic Acids Research
Mechanisms of gene repression by transforming growth factor-beta (TGF-beta) are not well understood. TGF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells. Repression is mediated by SMAD3 through interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca647e486142dacd7e2714c97234fb00
https://doi.org/10.1093/nar/gkm871
https://doi.org/10.1093/nar/gkm871
Autor:
Vedang A. Londhe, Hao Hao Huang, David Warburton, Nian-Ling Zhu, Changgong Li, Nora Heisterkamp, Matthew Sebald, Parviz Minoo, Saverio Bellusci
Publikováno v:
Gene. 393:70-80
Bone Morphogenetic Proteins are key signaling molecules in vertebrate development. Little is known about Bmp gene regulation in any organ. In Drosophila, the Bmp gene, dpp is regulated by Dorsal, the invertebrate homologue of Rel-NF-kB. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606bd6a5db860b658ec5918e39710012
https://doi.org/10.1016/j.gene.2007.01.016
https://doi.org/10.1016/j.gene.2007.01.016
Autor:
Fritz Costa, Jason Chua, Toshiaki Shichinohe, Stephanie Schmitmeier, Nian Ling Zhu, Weijun Wang, Noriyuki Kasahara, Thomas C. Chen, Barbara A. Sosnowski, Steve Swenson
Publikováno v:
Journal of Neurosurgery. 103:1058-1066
Object. Adenovirus vector (AdV)—mediated gene delivery has been recently demonstrated in clinical trials as a novel potential treatment for malignant gliomas. Combined coxsackievirus B and adenovirus receptor (CAR) has been shown to function as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033d54eea63fa44f5995af24bfc96f23
https://doi.org/10.3171/jns.2005.103.6.1058
https://doi.org/10.3171/jns.2005.103.6.1058
Publikováno v:
Gene. 327:25-36
Bone morphogenetic protein 4, BMP4, plays an important role in the development of various organs including the lungs. Little is known regarding the regulation of Bmp4 gene expression in any organ. In the lung, indirect evidence indicates that NKX2.1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f190f8702513477b6726523770941ace
https://doi.org/10.1016/j.gene.2003.11.013
https://doi.org/10.1016/j.gene.2003.11.013
Autor:
Nian Ling Zhu, Erlinda M. Gordon, Maria Stapfer, Frederick L. Hall, Robert W. Beart, Liqiong Liu, Wayne F. Anderson
Publikováno v:
Human Gene Therapy. 11:983-993
A major obstacle that limits the potential of human gene therapy is the inefficiency of gene delivery to appropriate sites in vivo. Previous studies demonstrated that the physiological surveillance function performed by von Willebrand factor (vWF) co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0262f964bd443b5257b076163f676355
https://doi.org/10.1089/10430340050015293
https://doi.org/10.1089/10430340050015293
Publikováno v:
Neurosurgical Focus. 8:1-8
Object The use of gene therapy for the treatment of malignant gliomas has been disappointing. In an effort to increase the viral transduction efficiency in delivering cytotoxic genes to malignant gliomas, the authors have used a novel retargeting sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eefc5ba5064399d4dc3611c90345fd2a
https://doi.org/10.3171/foc.2000.8.4.5
https://doi.org/10.3171/foc.2000.8.4.5
Autor:
David R. Hinton, Erlinda M. Gordon, Nian-Ling Zhu, Gene Hung, Vernon T. Tolo, Michael J. Skotzko, Daniel S. Chen, W. French Anderson, Frederick L. Hall
Publikováno v:
Human Gene Therapy. 8:1667-1674
Metastatic osteosarcoma is a potential target for gene therapy, because conventional therapies are only palliative and metastatic disease is invariably fatal. Overexpression of the cyclin G1 (CYCG1) gene is frequently observed in human osteosarcoma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a45bc6b5f13979aa856336e2ee290f
https://doi.org/10.1089/hum.1997.8.14-1667
https://doi.org/10.1089/hum.1997.8.14-1667
Autor:
Wayne F. Anderson, Lan-Ying Wu, Erlinda M. Gordon, Peng Xuan Liu, Nian Ling Zhu, Frederick L. Hall, Vaughn A. Starnes
Publikováno v:
Circulation. 96:628-635
Background The contemporary treatment of coronary athero-occlusive disease by percutaneous transluminal coronary angioplasty is hampered by maladaptive wound healing, resulting in significant failure rates. Morbid sequelae include smooth muscle cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115789d8ff3385c2f1985a164ce0dab4
https://doi.org/10.1161/01.cir.96.2.628
https://doi.org/10.1161/01.cir.96.2.628