Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Nian-Kang Sun"'
Publikováno v:
Cancer Science. 113:2616-2626
More than 90% of ovarian cancer deaths are due to relapse following development of chemoresistance. Our main objective is to better understand the molecular mechanism underlying paclitaxel resistance (taxol resistance, Txr) in ovarian cancer. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326732dccde64dca2f8ee34ce2eea2db
https://doi.org/10.1111/cas.15448
https://doi.org/10.1111/cas.15448
Autor:
Chuck C.-K. Chao, Chau-Ting Yeh, Ya-Hui Huang, Jing-You Guo, Nian-Kang Sun, Chia-Jung Li, Li-Feng Lu, Yu-Chin Liu
The investigation of HBx and RHAMM regulation on cell motility via Transwell assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a1b21af40f69c55b11acce6f3797ed
https://doi.org/10.1158/1541-7786.22513918.v1
https://doi.org/10.1158/1541-7786.22513918.v1
Autor:
Chuck C.-K. Chao, Chau-Ting Yeh, Ya-Hui Huang, Jing-You Guo, Nian-Kang Sun, Chia-Jung Li, Li-Feng Lu, Yu-Chin Liu
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3690e90794ef816765917fc56b4d8ac
https://doi.org/10.1158/1541-7786.22513909.v1
https://doi.org/10.1158/1541-7786.22513909.v1
Autor:
Chuck C.-K. Chao, Chau-Ting Yeh, Ya-Hui Huang, Jing-You Guo, Nian-Kang Sun, Chia-Jung Li, Li-Feng Lu, Yu-Chin Liu
Additional materials and methods information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755ac3e096809b0b60d1de87e426bdca
https://doi.org/10.1158/1541-7786.22513906
https://doi.org/10.1158/1541-7786.22513906
Publikováno v:
Biochemical Pharmacology. 212:115581
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c6ec8081bbc079b88159cd3a53c947
https://doi.org/10.1016/j.bcp.2023.115581
https://doi.org/10.1016/j.bcp.2023.115581
Publikováno v:
Biochemical pharmacology. 177
Toll-like receptor 4 (TLR4) is often overexpressed in taxol-resistant cancer cells. Here we used whole-genome transcriptomic analysis to identify 787 upregulated genes in SKOV3 ovarian carcinoma cells that ectopically express TLR4. Using chromatin im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41abb6179fb6ffdb3f1c50eef0772cfc
https://pubmed.ncbi.nlm.nih.gov/32278794
https://pubmed.ncbi.nlm.nih.gov/32278794
Publikováno v:
Journal of Cellular Physiology. 233:2489-2501
We report here that toll-like receptor 4 (TLR4) and ABCB1 are upregulated in SKOV3 ovarian carcinoma cells that acquired resistance to the anticancer drug taxol. Silencing of TLR4 using short-hairpin RNA sensitized taxol-resistant SKOV3 cells to taxo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605743a4dd25613f19e02bba6b18b932
https://doi.org/10.1002/jcp.26125
https://doi.org/10.1002/jcp.26125
Autor:
Li-Feng Lu, Nian-Kang Sun, Chia-Jung Li, Yu-Chin Liu, Ya-Hui Huang, Chau-Ting Yeh, Jing-You Guo, Chuck C.-K. Chao
Publikováno v:
Molecular cancer research : MCR. 18(3)
Chronic hepatitis B virus (HBV) infection is a major risk factor for the development of hepatocellular carcinoma (HCC), which represents one of the most common cancers worldwide. Recent studies suggest that HBV's protein X (HBx) plays a crucial role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69869ccb3d9c4b7d7f7f3a897ceea57
https://pubmed.ncbi.nlm.nih.gov/31792079
https://pubmed.ncbi.nlm.nih.gov/31792079
Publikováno v:
Biochemical Pharmacology. 186:114456
Ovarian cancer is poorly treatable due, at least in part, to induced drug resistance to taxol- and cisplatin-based chemotherapy. Recent studies showed that ectopic overexpression of toll-like receptor 4 (TLR4) in ovarian cancer cells leads to upregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2adbb596ac193817002c8383cd8046
https://doi.org/10.1016/j.bcp.2021.114456
https://doi.org/10.1016/j.bcp.2021.114456
Publikováno v:
Journal of cellular physiology. 234(6)
We report here that the androgen receptor (AR) and ABCB1 are upregulated in a model of acquired taxol resistance (txr) in ovarian carcinoma cells. AR silencing sensitizes txr cells to taxol threefold, whereas ectopic AR expression in AR-null HEK293 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e43b5440efda3cd65ecf5d007ed58a
https://pubmed.ncbi.nlm.nih.gov/30317630
https://pubmed.ncbi.nlm.nih.gov/30317630