Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Nian Qing Shi"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The authors have previously shown that membrane voltage can influence embryonic patterning during development. Here, the authors computationally model how nicotine disrupts Xenopus embryogenesis by perturbing voltage gradients, and rescue nicotine-in
Externí odkaz:
https://doaj.org/article/e30cbd3fc0a9494ba626b09310562894
Autor:
Vaibhav P. Pai, Valerie Willocq, Emily J. Pitcairn, Joan M. Lemire, Jean-François Paré, Nian-Qing Shi, Kelly A. McLaughlin, Michael Levin
Publikováno v:
Biology Open, Vol 6, Iss 10, Pp 1445-1457 (2017)
Laterality is a basic characteristic of all life forms, from single cell organisms to complex plants and animals. For many metazoans, consistent left-right asymmetric patterning is essential for the correct anatomy of internal organs, such as the hea
Externí odkaz:
https://doaj.org/article/689a0e604839463a8dcd34890ee2ff83
Autor:
Emily Pitcairn, Hannah Harris, Justine Epiney, Vaibhav P. Pai, Joan M. Lemire, Bin Ye, Nian-Qing Shi, Michael Levin, Kelly A. McLaughlin
Publikováno v:
Communicative & Integrative Biology, Vol 10, Iss 3 (2017)
Hyperpolarization-activated cyclic-nucleotide gated channel (HCN) proteins are important regulators of both neuronal and cardiac excitability. Among the 4 HCN isoforms, HCN4 is known as a pacemaker channel, because it helps control the periodicity of
Externí odkaz:
https://doaj.org/article/6df9eb21a182468c85912c8b74a66107
Autor:
Valerie Willocq, Nian-Qing Shi, Kelly A. McLaughlin, Jean-François Paré, Emily J. Pitcairn, Joan M. Lemire, Vaibhav P. Pai, Michael Levin
Publikováno v:
Biology Open, Vol 6, Iss 10, Pp 1445-1457 (2017)
Biology Open
Biology Open
Laterality is a basic characteristic of all life forms, from single cell organisms to complex plants and animals. For many metazoans, consistent left-right asymmetric patterning is essential for the correct anatomy of internal organs, such as the hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b59913b2ef05465e13cd381021a35b4
http://bio.biologists.org/content/6/10/1445
http://bio.biologists.org/content/6/10/1445
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Endogenous bioelectrical signaling coordinates cell behaviors toward correct anatomical outcomes. Lack of a model explaining spatialized dynamics of bioelectric states has hindered the understanding of the etiology of some birth defects and the devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfdca4ea9bdfaa401d3defa1579a3c03
http://europepmc.org/articles/PMC5843655
http://europepmc.org/articles/PMC5843655
Autor:
Hannah Harris, Justine Epiney, Joan M. Lemire, Nian-Qing Shi, Kelly A. McLaughlin, Vaibhav P. Pai, Emily J. Pitcairn, Michael Levin, Bin Ye
Publikováno v:
Communicative & Integrative Biology
Communicative & Integrative Biology, Vol 10, Iss 3 (2017)
Communicative & Integrative Biology, Vol 10, Iss 3 (2017)
Hyperpolarization-activated cyclic-nucleotide gated channel (HCN) proteins are important regulators of both neuronal and cardiac excitability. Among the 4 HCN isoforms, HCN4 is known as a pacemaker channel, because it helps control the periodicity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04052c60a4a5bb335b9cb2dc100e8156
http://europepmc.org/articles/PMC5501196
http://europepmc.org/articles/PMC5501196
Publikováno v:
Channels. 7:493-502
Cardiac ATP-sensitive potassium channels (KATP) are found in both the sarcoplasmic reticulum (sarcKATP) and the inner membrane of mitochondria (mitoKATP). SarcKATP are composed of a pore containing subunit Kir6.2 and a regulatory sulfonylurea recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c92306ddeb33ae50d95988798791da
https://doi.org/10.4161/chan.26181
https://doi.org/10.4161/chan.26181
Autor:
Zheng Wang, Jing-Qiong Kang, Michael X. Wang, Nian Qing Shi, Dong Xu, Joseph Luttrell, Juexin Wang, Saad M. Khan, Ning Zhang
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811015021
Protein structure prediction and modeling provide a tool for understanding protein functions by computationally constructing protein structures from amino acid sequences and analyzing them. With help from protein prediction tools and web servers, use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02fba98f926f45562aaf0731aa9783b
https://pubmed.ncbi.nlm.nih.gov/27807743
https://pubmed.ncbi.nlm.nih.gov/27807743
Autor:
Jonathan C. Makielski, Stacie Kroboth, Bin Ye, Jianding Cheng, Nian-Qing Shi, Feng Zhou, Ping Yuan, Bi-Hua Tan
Publikováno v:
American Journal of Forensic Medicine & Pathology. 32:359-363
Based on autopsy data collected in Southern China from 2001-2006, 975 cases of sudden unexplained nocturnal death syndrome (SUNDS) were surveyed. Genetic screening of SCN5A gene encoding the voltage dependent cardiac sodium channel was performed in 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348833b4adaa345d2fc1c4e49f2ceb0b
https://doi.org/10.1097/paf.0b013e3181d03d02
https://doi.org/10.1097/paf.0b013e3181d03d02
Autor:
Elizabeth M. McNally, Nitin T. Aggarwal, Stacie Kroboth, Jie Lin Pu, Jonathan C. Makielski, J. Jason Sims, Nian Qing Shi, Bin Ye
Publikováno v:
Circulation Research. 105:1083-1093
Rationale : Cardioprotective pathways may involve a mitochondrial ATP-sensitive potassium (mitoK ATP ) channel but its composition is not fully understood. Objective : We hypothesized that the mitoK ATP channel contains a sulfonylurea receptor (SUR)2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b020837b88790ad989cd6ff5ec606d
https://doi.org/10.1161/circresaha.109.195040
https://doi.org/10.1161/circresaha.109.195040