Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Niamh Mannion"'
Autor:
Matthew E. Massett, Laura Monaghan, Shaun Patterson, Niamh Mannion, Roderick P. Bunschoten, Alex Hoose, Sandra Marmiroli, Robert M. J. Liskamp, Heather G. Jørgensen, David Vetrie, Alison M. Michie, Xu Huang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-16 (2021)
Abstract Epigenomic dysregulation is a common pathological feature in human hematological malignancies. H3K9me3 emerges as an important epigenomic marker in acute myeloid leukemia (AML). Its associated methyltransferases, such as SETDB1, suppress AML
Externí odkaz:
https://doaj.org/article/c6caf5a67a024f7385a2936b34f65413
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 2338-2362 (2015)
The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA. Inosine can have a profound effect on the RNAs that are edited, not only changing the base-pairing prope
Externí odkaz:
https://doaj.org/article/3b463ad5cb01461e858079450079e1f7
Autor:
Alison M. Michie, Xu Huang, David Vetrie, Laura Monaghan, Alex Hoose, Niamh Mannion, Roderick P. Bunschoten, Matthew E. Massett, Shaun David Patterson, Rob M. J. Liskamp, Sandra Marmiroli, Heather G. Jørgensen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
Epigenomic dysregulation is a common pathological feature in human hematological malignancies. H3K9me3 emerges as an important epigenomic marker in acute myeloid leukemia (AML). Its associated methyltransferases, such as SETDB1, suppress AML leukemog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29006c78f23e4a54d99ede8f7f8c80e5
https://doi.org/10.1038/s41419-021-03738-0
https://doi.org/10.1038/s41419-021-03738-0
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 2338-2362 (2015)
Biomolecules
Biomolecules
The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA. Inosine can have a profound effect on the RNAs that are edited, not only changing the base-pairing prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328929b0f2aba1429e667563b77214f4
http://www.mdpi.com/2218-273X/5/4/2338
http://www.mdpi.com/2218-273X/5/4/2338
Autor:
Matthew E. Massett, Laura Monaghan, Rob M. J. Liskamp, Xu Huang, David Vetrie, Sandra Marmiroli, Alison M. Michie, Joana Bittencourt-Silvestre, Niamh Mannion
Publikováno v:
Blood. 132:3879-3879
Acute Myeloid Leukemia (AML) is an aggressive heterogeneous hematological malignancy. Persistence of leukemia stem cells (LSC) drive AML leukemogenesis, responsible for drug resistance and disease relapse following conventional chemotherapy. Growing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::936881e1a5437e4fdcc721d7386b9bcc
https://doi.org/10.1182/blood-2018-99-111256
https://doi.org/10.1182/blood-2018-99-111256
Publikováno v:
PLOS Genetics
PLoS Genetics
PLoS Genetics, Vol 11, Iss 12, p e1005687 (2015)
PLoS Genetics
PLoS Genetics, Vol 11, Iss 12, p e1005687 (2015)
Our knowledge of the variety and abundances of RNA base modifications is rapidly increasing. Modified bases have critical roles in tRNAs, rRNAs, translation, splicing, RNA interference, and other RNA processes, and are now increasingly detected in al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21bf6d7d4f074a7ffbdaf67a35f68d8e