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Autor:
Niamh Keon, Astrid Hoebertz, Marina Schorpp-Kistner, Peter Angel, Florian A. Karreth, Robert Eferl, Lukas Kenner, Erwin F. Wagner, F. Timo Beil, Agnieszka P. Szremska, Harald Scheuch, Michael Amling
Publikováno v:
The Journal of Cell Biology
Because JunB is an essential gene for placentation, it was conditionally deleted in the embryo proper. JunBDelta/Delta mice are born viable, but develop severe low turnover osteopenia caused by apparent cell-autonomous osteoblast and osteoclast defec