Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Niamh E. Kieran"'
Publikováno v:
Chimerism. 1:69-73
Renal transplantation is the treatment of choice for many patients with end stage renal disease. While significant progress has been achieved in short-term outcomes, long-term graft survival has only marginally improved. More than 50% of transplanted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a7e38c55784d852907a667dffbdcd4
https://doi.org/10.4161/chim.1.2.14293
https://doi.org/10.4161/chim.1.2.14293
Autor:
Susan M. O’Reilly, Marc Pouliot, Cormac T. Taylor, Martin O. Leonard, Katrina M. Comerford, Sean B. Lee, Niamh E. Kieran, Eoin P. Cummins
Publikováno v:
American Journal of Physiology-Cell Physiology. 290:C592-C600
Hypoxia occurs during a number of conditions in which altered epithelial proliferation is critical, including tumor development. Microarray analysis of colon-derived epithelial cells revealed a hypoxia-dependent increase in the expression of amphireg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46a1cc8936cb72caca22a811b97e655
https://doi.org/10.1152/ajpcell.00278.2005
https://doi.org/10.1152/ajpcell.00278.2005
Autor:
Hamid Rabb, Niamh E. Kieran
Publikováno v:
Journal of Investigative Medicine. 52:310-314
Organ preservation and reperfusion injury have significant detrimental effects on both short- and long-term organ function. Ischemia reperfusion injury (IRI) underlies organ transplant dysfunction, myocardial infarction, stroke, and shock. Multiple m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a21e994a04612be6d9f7744b8152ade
https://doi.org/10.1136/jim-52-05-30
https://doi.org/10.1136/jim-52-05-30
Autor:
Yiping Wang, Hugh R. Brady, Lukas Kairaitis, Denise M. Sadlier, Sarah A. Roxburgh, Susan B. Connolly, David Harris, Niamh E. Kieran, Peter Doran, Derek P. Brazil
Publikováno v:
Journal of Biological Chemistry. 279:29670-29680
Transcriptome analysis using microarray technology represents a powerful unbiased approach for delineating pathogenic mechanisms in disease. Here molecular mechanisms of renal tubulointerstitial fibrosis (TIF) were probed by monitoring changes in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885e32aa178f38f3a3098780d2374ae6
https://doi.org/10.1074/jbc.m313408200
https://doi.org/10.1074/jbc.m313408200
Publikováno v:
Kidney International. 65:1145-1154
Lipoxins: Potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease. Lipoxins are lipoxygenase-derived lipid mediators with both anti-inflammatory and proresolution properties that have been demonstrated in vivo and in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe36c2a037453334baf6e3d2f9b8a3a
https://doi.org/10.1111/j.1523-1755.2004.00487.x
https://doi.org/10.1111/j.1523-1755.2004.00487.x
Publikováno v:
Journal of the American Society of Nephrology. 14:S279-S283
Diabetes is an escalating problem worldwide and a major cause of vascular disease, renal failure, and blindness, among other complications. The cellular mediators of high glucose-induced injury include activation of protein kinase C, accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59b1ecc64518f270a13983ed189e5b9
https://doi.org/10.1097/01.asn.0000078022.77369.eb
https://doi.org/10.1097/01.asn.0000078022.77369.eb
Autor:
Martin O. Leonard, Niamh E. Kieran, Katherine Howell, Melissa J. Burne, Raghu Varadarajan, Saravanakumar Dhakshinamoorthy, Alan G. Porter, Cliona O'Farrelly, Hamid Rabb, Cormac T. Taylor
Publikováno v:
The FASEB Journal. 20:2624-2626
Tissue reoxygenation following hypoxia is associated with ischemia-reperfusion injury (IRI) and may signal the development of ischemic preconditioning, an adaptive state that is protective against subsequent IRI. Here we used microarray RNA analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9609eba058463c6923c0c0793e7826
https://doi.org/10.1096/fj.06-5097fje
https://doi.org/10.1096/fj.06-5097fje
Autor:
Julio I. Osende, Peter Doran, Jesús Egido, Susan B. Connolly, Declan D. Sugrue, Niamh E. Kieran, Denise M. Sadlier, Alberto Lázaro, Julio Gallego-Delgado, Hugh R. Brady
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 32(5)
Left ventricular hypertrophy (LVH), a common consequence of systemic hypertension associated with poor clinical outcome, is also a potentially reversible condition. Here, we probed the molecular pathways that underpin the development of LVH and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a510aa864704e9d749145dca4b562f62
https://pubmed.ncbi.nlm.nih.gov/19325563
https://pubmed.ncbi.nlm.nih.gov/19325563
Autor:
Niamh E. Kieran, Hugh R. Brady
Publikováno v:
Seminars in Dialysis. 12:275-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b944b4d958f302248205576d5d282645
https://doi.org/10.1046/j.1525-139x.1999.99039.x
https://doi.org/10.1046/j.1525-139x.1999.99039.x
Autor:
Hamid Rabb, Cormac T. Taylor, Catherine Godson, Matthias Kretzler, Susan B. Connolly, Peter Doran, Debra F. Higgins, Anna Henger, Hugh R. Brady, Marie Claire Greenan, Niamh E. Kieran, Martin O. Leonard, Melissa J. Burne
Publikováno v:
Kidney International. (2):480-492
Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog. Background Lipoxins are lipoxygenase-derived eicosanoids with anti-inflammatory and proresolution bioactivities in vitro and in vivo. We have previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5b1d9dcf2345a02d0ab3927de44730