Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Niamh B. McNamara"'
Autor:
Georgina A. Craig, Lucy Ryan, Jessica Thapar, Niamh B. McNamara, Alana Hoffmann, Danielle Page, Jamie Rose, Simon R. Cox, Veronique E. Miron
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The structural integrity of myelin sheaths in the central nervous system (CNS) is crucial for the maintenance of its function. Electron microscopy (EM) is the gold standard for visualizing individual myelin sheaths. However, the tissue processing inv
Externí odkaz:
https://doaj.org/article/5604a8ff881640db8ef279fd21e834c1
Autor:
Sandra Amor, Niamh B. McNamara, Emma Gerrits, Manuel C. Marzin, Susanne M. Kooistra, Veronique E. Miron, Erik Nutma
Publikováno v:
Amor, S, McNamara, N B, Gerrits, E, Marzin, M C, Kooistra, S M, Miron, V E & Nutma, E 2022, ' White matter microglia heterogeneity in the CNS ', Acta Neuropathologica, vol. 143, no. 2, pp. 125-141 . https://doi.org/10.1007/s00401-021-02389-x
Microglia, the resident myeloid cells in the central nervous system (CNS) play critical roles in shaping the brain during development, responding to invading pathogens, and clearing tissue debris or aberrant protein aggregations during ageing and neu
Autor:
Niamh B. McNamara, David A. D. Munro, Nadine Bestard-Cuche, Akiko Uyeda, Jeroen F. J. Bogie, Alana Hoffmann, Rebecca K. Holloway, Irene Molina-Gonzalez, Katharine E. Askew, Stephen Mitchell, William Mungall, Michael Dodds, Carsten Dittmayer, Jonathan Moss, Jamie Rose, Stefan Szymkowiak, Lukas Amann, Barry W. McColl, Marco Prinz, Tara L. Spires-Jones, Werner Stenzel, Karen Horsburgh, Jerome J. A. Hendriks, Clare Pridans, Rieko Muramatsu, Anna Williams, Josef Priller, Veronique E. Miron
Publikováno v:
Nature 613(7942), 120-129 (2023). doi:10.1038/s41586-022-05534-y
Myelin is required for the function of neuronal axons in the central nervous system, but the mechanisms that support myelin health are unclear. Although macrophages in the central nervous system have been implicated in myelin health1, it is unknown w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228d404a8611c8450df3d12b1580b5c6
Autor:
Veronique E. Miron, Niamh B. McNamara
Publikováno v:
Neuron. 109:2204-2206
In this issue of Neuron, Chen et al. (2021) reveal dynamic changes in myelin in an Alzheimer's disease (AD) mouse model. Enhancing myelination genetically or pharmacologically improves cognition in this model, supporting myelin as a therapeutic targe
Autor:
Sandra, Amor, Niamh B, McNamara, Emma, Gerrits, Manuel C, Marzin, Susanne M, Kooistra, Veronique E, Miron, Erik, Nutma
Publikováno v:
Acta neuropathologica. 143(2)
Microglia, the resident myeloid cells in the central nervous system (CNS) play critical roles in shaping the brain during development, responding to invading pathogens, and clearing tissue debris or aberrant protein aggregations during ageing and neu
Autor:
Niamh B. McNamara, Veronique E. Miron
Publikováno v:
Neuroscience Letters. 714:134539
Perinatal brain injury (PBI) to the developing white matter results in hypomyelination of axons and can cause long-term motor and cognitive deficits e.g. cerebral palsy. There are currently no approved therapies aimed at repairing the white matter fo