Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Niall P Murphy"'
Autor:
Wenjia Wang, Mickaël Guedj, Viviane Bertrand, Julie Foucquier, Elisabeth Jouve, Daniel Commenges, Cécile Proust-Lima, Niall P Murphy, Olivier Blin, Laurent Magy, Daniel Cohen, Shahram Attarian
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169878 (2017)
The Charcot-Marie-Tooth Neuropathy Score (CMTNS) was developed as a main efficacy endpoint for application in clinical trials of Charcot-Marie-Tooth disease type 1A (CMT1A). However, the sensitivity of the CMTNS for measuring disease severity and pro
Externí odkaz:
https://doaj.org/article/1ed5e395f7894e9c845085b6ded2e1f7
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180907 (2017)
It has been hypothesized that brain development during adolescence perturbs reward processing in a way that may ultimately contribute to the risky decision making associated with this stage of life, particularly in young males. To investigate potenti
Externí odkaz:
https://doaj.org/article/566f0d3d32c7464ba9803b24d648dece
Autor:
Yuki eKobayashi, Yoshitake eSano, Elisabetta eVannoni, Hiromichi eGoto, Toshio eIkeda, Hitomi eSuzuki, Atsuko eOba, Hiroaki eKawasaki, Shigenobu eKanba, Hans-Peter eLipp, Niall P Murphy, David P Wolfer, Shigeyoshi eItohara
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
The habenular complex linking forebrain and midbrain structures is subdivided into the medial (mHb) and the lateral nuclei (lHb). The mHb is characterized by the expression of specific nicotinic acetylcholine receptor isoforms and the release of acet
Externí odkaz:
https://doaj.org/article/ef95266c9e41474a9166d0244bd9858c
Autor:
Courtney S. Wilkinson, Harrison L. Blount, Shane Davis, Giselle Rojas, Lizhen Wu, Niall P. Murphy, Marek Schwendt, Lori A. Knackstedt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we assessed whether co-consumption of oxycodone and alcohol influence the intake of one another, demand for oxycodone, and the neurocircuitry underlying cue-p
Externí odkaz:
https://doaj.org/article/5f92b4f2f79e4a2a9510606116d19623
Autor:
Ariana C. Brice-Tutt, Darrice S. Montgomery, Cassidy M. Kramer, Peter M. Novotny, Wendi L. Malphurs, Abhisheak Sharma, Robert. M. Caudle, Adriaan W. Bruijnzeel, Barry Setlow, John K. Neubert, Niall P. Murphy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential. Here we studied rats as they underwent a series of pain- and reward-related tests: c
Externí odkaz:
https://doaj.org/article/1425e38455d0434487e5d384057c23da
Autor:
Kei-ichi Katayama, Naoko Morimura, Katsunori Kobayashi, Danielle Corbett, Takehito Okamoto, Veravej G. Ornthanalai, Hayato Matsunaga, Wakako Fujita, Yoshifumi Matsumoto, Takumi Akagi, Tsutomu Hashikawa, Kazuyuki Yamada, Niall P. Murphy, Soichi Nagao, Jun Aruga
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104604- (2022)
Summary: SLITRK2 encodes a transmembrane protein that modulates neurite outgrowth and synaptic activities and is implicated in bipolar disorder. Here, we addressed its physiological roles in mice. In the brain, the Slitrk2 protein was strongly detect
Externí odkaz:
https://doaj.org/article/4c551bbb671f4e9d99a3161fe1d0f72d
Autor:
Niall P. Murphy, Darrice S. Montgomery, Ariana C. Brice-Tutt, Cassidy M. Kramer, Peter M. Novotny, Wendi Malphurs, Robert M. Caudle, Adriaan W. Bruijnzeel, Abhisheak Sharma, Barry Setlow, John K. Neubert
Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential. Here we studied rats as they underwent a series of pain- and reward-related tests: cutaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a0dbab4b038365d0cb938bb9755add
https://doi.org/10.21203/rs.3.rs-2679319/v1
https://doi.org/10.21203/rs.3.rs-2679319/v1
Autor:
Farzad Mortazavi, Nigel T. Maidment, Linda Tsan, Franziska Richter, Caitlyn K. Mulligan, Lauryn Gabby, Pedrom C. Sioshansi, Larry C. Ackerson, Krystal De La Rosa, Marie-Françoise Chesselet, Ingrid C. Cely, Niall P. Murphy, Kimberly A. McDowell
Publikováno v:
Neurobiology of Aging. 51:54-66
How genetic variations in the dopamine transporter (DAT) combined with exposure to environmental toxins modulate the risk of Parkinson's disease remains unclear. Using unbiased stereology in DAT knock-down mice (DAT-KD) and wild-type (WT) littermates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95bff011fe21c7af1bb0a43cdd72307
https://doi.org/10.1016/j.neurobiolaging.2016.11.015
https://doi.org/10.1016/j.neurobiolaging.2016.11.015
Publikováno v:
Behavioural Pharmacology. 27:516-527
Opioid peptides are implicated in processes related to reward and aversion; however, how specific opioid peptides are involved remains unclear. We investigated the role of nociceptin (NOC) in voluntary licking for palatable and aversive tastants by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689158fb00b3e93dcd9817465ff2aba4
https://doi.org/10.1097/fbp.0000000000000240
https://doi.org/10.1097/fbp.0000000000000240
Autor:
Alisa R. Kosheleff, Niall P. Murphy, Sean B. Ostlund, Linda Tsan, Jingwen Araki, Nigel T. Maidment, Grace Chen
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Frontiers in Psychiatry
Frontiers in Psychiatry
There is growing evidence that repeated consumption of highly palatable, nutritionally poor “junk food” diets can produce deficits in cognition and behavioral control. We explored whether long-term junk-food diet exposure disrupts rats' ability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817509afcb39888b87abfe2b99be3f91
https://doi.org/10.3389/fpsyt.2018.00350
https://doi.org/10.3389/fpsyt.2018.00350