Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Niall P Hyland"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
The emerging links between our gut microbiome and the central nervous system are regarded as a paradigm shift in neuroscience with possible implications for not only understanding the pathophysiology of stress-related psychiatric disorders, but also
Externí odkaz:
https://doaj.org/article/e04a6c4ae70341d7a8939528ac5ec996
Autor:
Jonathan M. Keane, Philana Fernandes, Florian Kratz, Grace O'Callaghan, Cormac G. M. Gahan, Susan A. Joyce, Catherine Stanton, Niall P. Hyland, Aileen Houston
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Although classically recognized as a neurotransmitter, gamma aminobutyric acid (GABA) has also been identified in colonic tumors. Moreover, the gut microbiome represents another potential source of GABA. Both GABAA and GABAB receptors have b
Externí odkaz:
https://doaj.org/article/b0d23d6d3f01418fa17e21750bd230e5
Autor:
Niall P Hyland, John F Cryan
Publikováno v:
Frontiers in Pharmacology, Vol 1 (2010)
Gamma-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the body and hence GABA-mediated neurotransmission regulates many physiological functions, including those in the gastrointestinal (GI) tract. GABA is located throughout the GI
Externí odkaz:
https://doaj.org/article/a0282678100a49b3b072c498216513fa
Autor:
Declan P McKernan, Aoife Nolan, Elizabeth K Brint, Siobhain M O'Mahony, Niall P Hyland, John F Cryan, Timothy G Dinan
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8226 (2009)
BackgroundIrritable bowel syndrome (IBS) is largely viewed as a stress-related disorder caused by aberrant brain-gut-immune communication and altered gastrointestinal (GI) homeostasis. Accumulating evidence demonstrates that stress modulates innate i
Externí odkaz:
https://doaj.org/article/0ee5709c37c64f76ac4beb5946299e1b
Autor:
Huimin Ye, Tarini S. Ghosh, Cara M. Hueston, Klara Vlckova, Anna V. Golubeva, Niall P. Hyland, Paul W. O’Toole
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTHuman aging is characterized by gut microbiome alteration and differential loss of gut commensal species associated with the onset of frailty. The administration of cultured commensal strains to replenish lost taxa could potentially promote h
Externí odkaz:
https://doaj.org/article/ca342f00e4ba4708bf0d6484736245cc
Autor:
Friederike Uhlig, Alicja K. Warda, Cara M. Hueston, Lorraine A. Draper, Gilles Chauvière, Erik Eckhardt, Colin Hill, Niall P. Hyland
Publikováno v:
Journal of Functional Foods, Vol 108, Iss , Pp 105730- (2023)
Lactobacillus LB is a postbiotic generated following fermentation by Limosilactobacillus fermentum and Lactobacillus delbrueckii. Lactobacillus LB alleviates acute diarrhoea and ameliorates the symptoms of irritable bowel syndrome. Here, we investiga
Externí odkaz:
https://doaj.org/article/0f7219395b1144d98a2b2466076a0825
Autor:
Anna V. Golubeva, Susan A. Joyce, Gerard Moloney, Aurelijus Burokas, Eoin Sherwin, Silvia Arboleya, Ian Flynn, Dmitry Khochanskiy, Angela Moya-Pérez, Veronica Peterson, Kieran Rea, Kiera Murphy, Olga Makarova, Sergey Buravkov, Niall P. Hyland, Catherine Stanton, Gerard Clarke, Cormac G.M. Gahan, Timothy G. Dinan, John F. Cryan
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 166-178 (2017)
Autism spectrum disorder (ASD) is one of the most prevalent neurodevelopmental conditions worldwide. There is growing awareness that ASD is highly comorbid with gastrointestinal distress and altered intestinal microbiome, and that host-microbiome int
Externí odkaz:
https://doaj.org/article/c4dc18ec1f4540bb8e8c6e012726f675
Autor:
James M. Collins, Niall P. Hyland, Gerard Clarke, Patrick Fitzgerald, Marcela Julio‐Pieper, David C. Bulmer, Timothy G. Dinan, John F. Cryan, Siobhain M. O'Mahony
Publikováno v:
Journal of Neurochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7dad928c005c32d0a993e2ef210b49
https://doi.org/10.1111/jnc.15804
https://doi.org/10.1111/jnc.15804
Autor:
Beatriz Lobo, Mónica Tramullas, Beate-C Finger, Kevin W Lomasney, Caroll Beltran, Gerard Clarke, Javier Santos, Niall P Hyland, Timothy G Dinan, John F Cryan
Publikováno v:
Journal of neurogastroenterology and motility. 29(1)
Chronic psychological stress affects gastrointestinal physiology which may underpin alterations in the immune response and epithelial transport, both functions are partly regulated by enteric nervous system. However, its effects on enteric neuroplast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd621f4455ec6043b6ad3fa87221f469
https://pubmed.ncbi.nlm.nih.gov/36606438
https://pubmed.ncbi.nlm.nih.gov/36606438
The metabolism of dietary tryptophan occurs locally in the gut primarily via host enzymes, with similar to 5% metabolized by gut microbes. Three major tryptophan metabolic pathways are serotonin (beyond the scope of this review), indole, kynurenine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec7e10910b970c631edbf2d7a3a7981
https://hdl.handle.net/10468/12531
https://hdl.handle.net/10468/12531
