Deep Learning in Searching the Spectroscopic Redshift of Quasars

Autor: Nia, F. Rastegar, Mirtorabi, M. T., Moradi, R., Sadr, A. Vafaei., Wang, Y.

Studying the cosmological sources at their cosmological rest-frames is crucial to track the cosmic history and properties of compact objects. In view of the increasing data volume of existing and upcoming telescopes/detectors, we here construct a 1--

Externí odkaz: http://arxiv.org/abs/2201.03393

The Shank/ProSAP N-Terminal (SPN) Domain of Shank3 Regulates Targeting to Postsynaptic Sites and Postsynaptic Signaling.

Autor: Woike D; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany., Tibbe D; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany., Hassani Nia F; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany., Martens V; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany., Wang E; Institute of Integrative Biology, University of Liverpool, Liverpool, UK., Barsukov I; Institute of Integrative Biology, University of Liverpool, Liverpool, UK., Kreienkamp HJ; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. kreienkamp@uke.de.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2024 Feb; Vol. 61 (2), pp. 693-706. Date of Electronic Publication: 2023 Sep 01.

Complete list of canonical post-transcriptional modifications in the Bacillus subtilis ribosome and their link to RbgA driven large subunit assembly.

Autor: Popova AM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Jain N; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030, USA.; INSITRO, 279 E Grand Ave., South San Francisco, CA 94080, USA., Dong X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Abdollah-Nia F; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Britton RA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030, USA., Williamson JR; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Oct 14; Vol. 52 (18), pp. 11203-11217.

Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.

Autor: Willim J; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Woike D; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Greene D; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Das S; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Pfeifer K; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Yuan W; Department of Pediatrics, Washington University in St Louis School of Medicine, St Louis, MO, USA., Lindsey A; Department of Pediatrics, Washington University in St Louis School of Medicine, St Louis, MO, USA., Itani O; Department of Pediatrics, Washington University in St Louis School of Medicine, St Louis, MO, USA., Böhme AL; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Tibbe D; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hönck HH; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hassani Nia F; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Zech M; Institute of Human Genetics, School of Medicine, Technical University of Munich, Munich, Germany.; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.; Institute for Advanced Study, Technical University of Munich, Garching, Germany., Brunet T; Institute of Human Genetics, School of Medicine, Technical University of Munich, Munich, Germany.; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany., Faivre L; Centre de Génétique et Centre de Référence Anomalies du Développement et Syndromes Malformatifs, FHU TRANSLAD, CHU Dijon-Bourgogne, Dijon, France.; INSERM-Université de Bourgogne-UMR1231 GAD, Dijon, France., Sorlin A; INSERM-Université de Bourgogne-UMR1231 GAD, Dijon, France.; Laboratoire de Génomique médicale, Centre NEOMICS, CHU Dijon Bourgogne, Dijon, France., Vitobello A; INSERM-Université de Bourgogne-UMR1231 GAD, Dijon, France.; Laboratoire de Génomique médicale, Centre NEOMICS, CHU Dijon Bourgogne, Dijon, France., Smol T; Univ. Lille, CHU Lille, ULR7364 - RADEME, Lille, France., Colson C; Univ. Lille, CHU Lille, ULR7364 - RADEME, Lille, France., Baranano K; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Schatz K; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Bayat A; Department of Epilepsy Genetics and Personalized Medicine, Danish Epilepsy Center, Dianalund, Denmark.; Department for Regional Health Research, University of Southern Denmark, Odense, Denmark.; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Schoch K; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Spillmann R; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Davis EE; Center for Human Disease Modeling, Duke University Medical Center, Durham, NC, USA.; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.; Departments of Pediatrics and Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Conboy E; Indiana University School of Medicine, Indianapolis, IN, USA., Vetrini F; Indiana University School of Medicine, Indianapolis, IN, USA., Platzer K; Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany., Neuser S; Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany., Gburek-Augustat J; Division of Neuropaediatrics, Hospital for Children and Adolescents, University of Leipzig Medical Center, Leipzig, Germany., Grace AN; Molecular and Human Genetics Department, Baylor College of Medicine, Houston, TX, USA., Mitchell B; Baylor College of Medicine in San Antonio, San Antonio, TX, USA., Stegmann A; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands., Sinnema M; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands., Meeks N; Children's Hospital Colorado, Division of Clinical Genetics & Metabolism, Aurora, CO, USA., Saunders C; Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, MO, USA.; School of Medicine, University of Missouri Kansas City, Kansas City, MO, USA.; Genomic Medicine Center, Children's Mercy Research Institute, Kansas City, MO, USA., Cadieux-Dion M; Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, MO, USA., Hoyer J; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Van-Gils J; Genetics Lab, Centre Hospitalier Universitaire (CHU) de Bordeaux, Bordeaux, France., de Sainte-Agathe JM; Genetics Lab, Centre Hospitalier Universitaire (CHU) de Bordeaux, Bordeaux, France., Thompson ML; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Bebin EM; University of Alabama at Birmingham, Birmingham, AL, USA., Weisz-Hubshman M; Molecular and Human Genetics Department, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital, Houston, Tx, USA., Tabet AC; Department of Genetics, APHP-Robert Debré University Hospital, Paris, France., Verloes A; Department of Genetics, APHP-Robert Debré University Hospital, Paris, France., Levy J; Department of Genetics, APHP-Robert Debré University Hospital, Paris, France., Latypova X; Department of Genetics, APHP-Robert Debré University Hospital, Paris, France., Harder S; Mass spectrometry and Proteome Analytics, Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Silverman GA; Department of Pediatrics, Washington University in St Louis School of Medicine, St Louis, MO, USA., Pak SC; Department of Pediatrics, Washington University in St Louis School of Medicine, St Louis, MO, USA., Schedl T; Department of Genetics, Washington University in St Louis School of Medicine, St Louis, MO, USA., Freson K; Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium., Mumford A; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Turro E; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Schlein C; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Shashi V; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Kreienkamp HJ; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Kreienkamp@uke.de.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 10; Vol. 15 (1), pp. 7909. Date of Electronic Publication: 2024 Sep 10.

Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans.

Autor: Hassani Nia F; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Woike D; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Bento I; EMBL Hamburg, c/o DESY, Hamburg, Germany., Niebling S; EMBL Hamburg, c/o DESY, Hamburg, Germany.; Centre for Structural Systems Biology, Hamburg, Germany., Tibbe D; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Schulz K; Institute of Cell and Systems Biology of Animals, University of Hamburg, Hamburg, Germany.; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hirnet D; Institute of Cell and Systems Biology of Animals, University of Hamburg, Hamburg, Germany., Skiba M; Institute of Cell and Systems Biology of Animals, University of Hamburg, Hamburg, Germany., Hönck HH; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Veith K; EMBL Hamburg, c/o DESY, Hamburg, Germany., Günther C; EMBL Hamburg, c/o DESY, Hamburg, Germany., Scholz T; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Bierhals T; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Driemeyer J; Department of Pediatrics, University Medical Center Eppendorf, Hamburg, Germany., Bend R; Prevention Genetics, Marshfield, WI, USA., Failla AV; UKE microscopic imaging facility (umif), University Medical Center Eppendorf, Hamburg, Germany., Lohr C; Institute of Cell and Systems Biology of Animals, University of Hamburg, Hamburg, Germany., Alai MG; EMBL Hamburg, c/o DESY, Hamburg, Germany.; Centre for Structural Systems Biology, Hamburg, Germany., Kreienkamp HJ; Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany. Kreienkamp@uke.de.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2024 Jun; Vol. 29 (6), pp. 1683-1697. Date of Electronic Publication: 2022 Nov 30.