Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ni Huiping Son"'
Autor:
Masayoshi Yokoyama, Toru Seo, Taesik Park, Hiroaki Yagyu, Yunying Hu, Ni Huiping Son, Ayanna S. Augustus, Reeba K. Vikramadithyan, Rajasekhar Ramakrishnan, Leslie K. Pulawa, Robert H. Eckel, Ira J. Goldberg
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 646-655 (2007)
Regulation of cholesterol metabolism in cultured cells and in the liver is dependent on actions of the LDL receptor. However, nonhepatic tissues have multiple pathways of cholesterol uptake. One possible pathway is mediated by LPL, an enzyme that pri
Externí odkaz:
https://doaj.org/article/73b75d3edfd34bc78433795ee5c6f423
Autor:
Xie, Yong, Gu, Zhen-Jie, Wu, Mao-Xiong, Huang, Tu-Cheng, Ou, Jing-Song, Ni, Huiping-Son, Lin, Mao-Huan, Yuan, Wo-Liang, Wang, Jing-Feng, Chen, Yang-Xin
Publikováno v:
In Life Sciences 15 December 2016 167:12-21
Autor:
Vincenza Cifarelli, Stoyan Ivanov, Yan Xie, Ni-Huiping Son, Brian T. Saunders, Terri A. Pietka, Trevor M. Shew, Jun Yoshino, Sinju Sundaresan, Nicholas O. Davidson, Ira J. Goldberg, Andrew E. Gelman, Bernd H. Zinselmeyer, Gwendalyn J. Randolph, Nada A. Abumrad
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 1, Pp 82-98 (2017)
Background & Aims: CD36 has immunometabolic actions and is abundant in the small intestine on epithelial, endothelial, and immune cells. We examined the role of CD36 in gut homeostasis by using mice null for CD36 (CD36KO) and with CD36 deletion speci
Externí odkaz:
https://doaj.org/article/993ebac733924e7e98ea9013188fb165
Autor:
Jide Oluwadare, Ainara G. Cabodevilla, Ni-Huiping Son, Yunying Hu, Adam E. Mullick, Michael Verano, Jose O. Alemán, Ravichandran Ramasamy, Ira J. Goldberg
Publikováno v:
Journal of Lipid Research. 63:100274
Lipid accumulation in nonadipose tissues can cause lipotoxicity, leading to cell death and severe organ dysfunction. Adipose triglyceride lipase (ATGL) deficiency causes human neutral lipid storage disease and leads to cardiomyopathy; ATGL deficiency
Autor:
Traci E. Lamoia, Ira J. Goldberg, Ni-Huiping Son, Gerald I. Shulman, Mario Kahn, Leigh Goedeke, Gary W. Cline, Ali Nasiri, Xian-Man Zhang
Publikováno v:
Diabetes. 70
The transmembrane protein, cluster of differentiation 36 (CD36), facilitates tissue fatty acid uptake and is highly expressed in a variety of different cell types, including endothelial cells (ECs). Loss of EC Cd36 reduces parenchymal long-chain fatt
Publikováno v:
Am J Transl Res
Endothelial cells (ECs) maintain vascular integrity and mediate vascular repair and angiogenesis, by which new blood vessels are formed from pre-existing blood vessels. Hyperglycemia has been shown to increase EC angiogenic potential. However, few st
Autor:
Ni-Huiping Son, Radha Ananthakrishnan, Shuiqing Yu, Raffay S Khan, Hongfeng Jiang, Ruiping Ji, Hirokazu Akashi, Qing Li, Karen O'Shea, Shunichi Homma, Ira J Goldberg, Ravichandran Ramasamy
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46549 (2012)
Aldose reductase (AR), an enzyme mediating the first step in the polyol pathway of glucose metabolism, is associated with complications of diabetes mellitus and increased cardiac ischemic injury. We investigated whether deleterious effects of AR are
Externí odkaz:
https://doaj.org/article/966e20a40a4042d0a4ef566495faf45d
Autor:
Xi-ping Ding, Brenda Dorcely, Ira J. Goldberg, Xiang Fang, Shi-Lian Hu, Ni-Huiping Son, Shi Yin
Publikováno v:
Journal of Diabetes and its Complications. 32:1027-1034
Objective Systemic inflammation contributes to cardiovascular disease in patients with type 2 diabetes, and elevated white blood cell (WBC) counts are an established risk factor. Our goal is to describe changes in WBCs and inflammatory markers after
Autor:
Eric R. Gamazon, Nada A. Abumrad, Ira J. Goldberg, Ni-Huiping Son, Eric Penrose, Pallavi Dhule, Charles R. Flynn, Kooresh I. Shoghi, Krzysztof L. Hyrc, Miriam Jacome-Sosa, Dmitri Samovski, Terri A. Pietka
Publikováno v:
Diabetes. 67:1272-1284
During reduced energy intake, skeletal muscle maintains homeostasis by rapidly suppressing insulin-stimulated glucose utilization. Loss of this adaptation is observed with deficiency of the fatty acid transporter CD36. A similar loss is also characte
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Under physiological conditions, endothelial cells (ECs) play an important role in maintaining vascular integrity by acting as non-thrombogenic and non-inflammatory cells. ECs also mediate vascular repair and angiogenesis, a process by which new blood