Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ni‐Yuan Zhang"'
Autor:
Da-Yong Hou, Dong-Bing Cheng, Ni-Yuan Zhang, Zhi-Jia Wang, Xing-Jie Hu, Xin Li, Mei-Yu Lv, Xiang-Peng Li, Ling-Rui Jian, Jin-Peng Ma, Taolei Sun, Zeng-Ying Qiao, Wanhai Xu, Hao Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Emerging evidence indicates that the activation of ferroptosis by glutathione peroxidase 4 (GPX4) inhibitors may be a prominent therapeutic strategy for tumor suppression. However, the wide application of GPX4 inhibitors in tumor therapy is
Externí odkaz:
https://doaj.org/article/35f9a585649e480eac19b76f73b79d50
Autor:
Da-Yong Hou, Man-Di Wang, Xing-Jie Hu, Zhi-Jia Wang, Ni-Yuan Zhang, Gan-Tian Lv, Jia-Qi Wang, Xiu-Hai Wu, Lu Wang, Hao Wang, Wanhai Xu
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 110-119 (2022)
Intraoperative fluorescence-based tumor imaging plays a crucial role in performing the oncological safe tumor resection with the advantage of differentiating tumor from normal tissues. However, the application of these fluorescence contrast agents in
Externí odkaz:
https://doaj.org/article/c7e50f66da344a80b6f837f934eeec15
Autor:
Da-Yong Hou, Man-Di Wang, Ni-Yuan Zhang, Shaoxin Xu, Zhi-Jia Wang, Xing-Jie Hu, Gan-Tian Lv, Jia-Qi Wang, Mei-Yu Lv, Li Yi, Lu Wang, Dong-Bing Cheng, Taolei Sun, Hao Wang, Wanhai Xu
Publikováno v:
Nano Letters. 22:3983-3992
Lysosome-targeting self-assembling prodrugs had emerged as an attractive approach to overcome the acquisition of resistance to chemotherapeutics by inhibiting lysosomal sequestration. Taking advantage of lysosomal acidification induced intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c40bf24755eddb881a2d528bd450008
https://doi.org/10.1021/acs.nanolett.2c00540
https://doi.org/10.1021/acs.nanolett.2c00540
Autor:
Hong-Wei An, Da-Yong Hou, Jia Yang, Zi-Qi Wang, Man-Di Wang, Rui Zheng, Ni-Yuan Zhang, Xing-Jie Hu, Zhi-Jia Wang, Lu Wang, Di Liu, Jun-Feng Hao, Wanhai Xu, Yuliang Zhao, Hao Wang
Publikováno v:
Science Advances. 9
Up to 75% of bladder cancer patients suffer from recurrence due to postoperative tumor implantation. However, clinically used Bacillus Calmette-Guerin (BCG) treatment failed to inhibit the recurrence. Here, we report a bispecific glycopeptide (bsGP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6f9ad71ac6d0f0099717d8e6179f47f
https://doi.org/10.1126/sciadv.abq8225
https://doi.org/10.1126/sciadv.abq8225
Autor:
Da‐Yong Hou, Ni‐Yuan Zhang, Man‐Di Wang, Shao‐Xin Xu, Zhi‐Jia Wang, Xing‐Jie Hu, Gan‐Tian Lv, Jia‐Qi Wang, Xiu‐Hai Wu, Lu Wang, Dong‐Bing Cheng, Hao Wang, Wanhai Xu
Publikováno v:
Angewandte Chemie. 134
Intravesical administration of first-line drugs has shown failure in the treatment of bladder cancer owing to the poor tumor retention time of chemotherapeutics. Herein, we report an intracellular hydrolytic condensation (IHC) system to construct lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f07fa68d587319fd8302c860e6b82f
https://doi.org/10.1002/ange.202116893
https://doi.org/10.1002/ange.202116893
Publikováno v:
Angewandte Chemie International Edition. 61
Precise and effective manipulation of protein functions still faces tremendous challenges. Herein we report a programmable peptide molecule, consisted of targeting and self-assembly modules, that enables specific and highly efficient assembly governe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff9d70983ae35fb9ffb44f4a122117a
https://doi.org/10.1002/anie.202113649
https://doi.org/10.1002/anie.202113649
Autor:
Dayong Hou, Man-Di Wang, Ni-Yuan Zhang, Hao Wang, Gan-Tian Lv, Wanhai Xu, Xing-Jie Hu, Li Yi, Ru-Xiang Li, Zhi-Jia Wang
Publikováno v:
Biomaterials. 278
Peptide drug conjugate (PDC) has emerged as one of the new generations of targeted therapeutics for cancer, which owns the advantages of improved drug targetability and reduced adverse effects compared with traditional chemotherapy. However, the poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4907abf1ef6f861e25c5cda78022f4f
https://pubmed.ncbi.nlm.nih.gov/34624753
https://pubmed.ncbi.nlm.nih.gov/34624753
Publikováno v:
Biomaterials. 287:121655
Aggregation-induced emission luminogens (AIEgens) possess enhanced fluorescence in highly aggregated states, thus enabling AIEgens as a promising module for highly emissive fluorescence biomaterials. So far, AIEgens-based nanomaterials and their hybr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b406af54440c02c5f390e64b1cf2a3
https://doi.org/10.1016/j.biomaterials.2022.121655
https://doi.org/10.1016/j.biomaterials.2022.121655
Publikováno v:
Angewandte Chemie International Edition. 57:8649-8653
The design and construction of multi-stimuli-responsive supramolecular nanoassemblies that can mimic and regulate the fundamental biological processes have become a focus of interest in supramolecular chemistry. In this work, a perfect combination ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666df347e15d4031a9e46cb3c8d087d8
https://doi.org/10.1002/anie.201804620
https://doi.org/10.1002/anie.201804620