Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nguyet-Minh Nguyen Le"'
Autor:
Nguyet-Minh Nguyen Le, Sarah Zsák, Bao Le-Vinh, Julian David Friedl, Gergely Kali, Patrick Knoll, Hartwig Wolfram Seitter, Alexandra Koschak, Andreas Bernkop-Schnürch
Publikováno v:
ACS Applied Materials & Interfaces. 14:44981-44991
This study aimed to develop phosphatase-responsive ζ potential converting nanocarriers utilizing polyphosphate-coated cell-penetrating peptide (CPP)-decorated nanoemulsions (NEs) as a novel gene delivery system to retinal cells.Poly-l-lysine (PLL) w
Akademický článek
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Autor:
Andreas Bernkop-Schnürch, Bao Le-Vinh, Nguyet-Minh Nguyen Le, Christian Steinbring, Barbara Matuszczak, Aamir Jalil
Publikováno v:
Journal of Colloid and Interface Science. 587:279-289
Aim It was the aim of this study to develop a zeta potential changing drug delivery system by decorating lipid-based nanocarriers with a polycationic cell penetrating peptide (CPP) and subsequently masking these cationic substructures with polyphosph
Autor:
Patrick Knoll, Nikolas Hörmann, Nguyet-Minh Nguyen Le, Richard Wibel, Ronald Gust, Andreas Bernkop-Schnürch
Publikováno v:
Journal of colloid and interface science. 628
The aim of this study was the development of nanostructured lipid carriers (NLCs) decorated with a polycationic cell-penetrating peptide (CPP). A coating with polyphosphates (PP) enables charge conversion at target cells being triggered by the membra
Akademický článek
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Autor:
Andreas Bernkop-Schnürch, Julian David Friedl, Sergey Zaichik, Nguyet-Minh Nguyen Le, Christian Steinbring
Publikováno v:
Nanomedicine. 15:1829-1841
Aim: Comparison of the impact of polyethylene glycol (PEG) and polyglycerol (PG) surface decoration on self-emulsifying drug delivery system (SEDDS)-membrane interaction and cellular uptake. Materials & methods: PEG-, PEG/PG- and PG-SEDDS were assess
Autor:
Julian David Friedl, Arne Matteo Jörgensen, Nguyet-Minh Nguyen Le, Christian Steinbring, Andreas Bernkop-Schnürch
Publikováno v:
International journal of pharmaceutics. 618
Evaluation of different polyhydroxy surfaces in SEDDS to overcome the limitations associated with conventional polyethylene glycol (PEG)-based SEDDS surfaces for intracellular drug delivery.Anionic, cationic and non-ionic polyglycerol- (PG-) and alky
Autor:
Nguyet-Minh Nguyen Le, Bao Le-Vinh, Julian David Friedl, Aamir Jalil, Gergely Kali, Andreas Bernkop-Schnürch
Publikováno v:
Carbohydrate polymers. 282
To prepare new polycationic pullulan derivatives exhibiting highly mucoadhesive and sustained drug release properties.Hydroxy groups of pullulan were activated with mesyl chloride followed by conjugation with low-molecular weight polyamines. Pullulan
Autor:
Andreas Bernkop-Schnürch, Imran Nazir, Barbara Matuszczak, Nguyet-Minh Nguyen Le, Bao Le-Vinh
Publikováno v:
International Journal of Biological Macromolecules. 133:647-655
Mucus permeation, mucoadhesion and cell membrane interaction are properties that a drug carrier needs to deliver macromolecule compounds through the mucus barrier and inside epithelial cells effectively. Herein, we prepared micelles from phosphorylat
Autor:
Barbara Matuszczak, Flavia Laffleur, Andreas Bernkop-Schnürch, Martina Tribus, Aamir Jalil, Nguyet-Minh Nguyen Le, Mulazim Hussain Asim
Publikováno v:
International Journal of Biological Macromolecules. 130:148-157
The aim of this study was to synthesize novel polymeric excipients forming mucoadhesive films for treatment of vaginal microbial infections. 2-(2-Amino ethyldisulfanyl) nicotinic acid was conjugated with gellan gum via amide bond formation. The struc