Epigenetic programming of host lipid metabolism associated with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis .

Autor: Dill-McFarland KA; Department of Medicine, University of Washington, Seattle, Washington, USA., Simmons JD; Department of Medicine, University of Washington, Seattle, Washington, USA., Peterson GJ; Department of Medicine, University of Washington, Seattle, Washington, USA., Nguyen FK; Department of Medicine, University of Washington, Seattle, Washington, USA., Campo M; Department of Medicine, University of Washington, Seattle, Washington, USA., Benchek P; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA., Stein CM; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Vaisar T; Department of Medicine, University of Washington, Seattle, Washington, USA., Mayanja-Kizza H; Department of Internal Medicine, Makerere University, Kampala, Uganda., Boom WH; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Hawn TR; Department of Medicine, University of Washington, Seattle, Washington, USA.

Publikováno v: MSystems [mSystems] 2024 Sep 17; Vol. 9 (9), pp. e0062824. Date of Electronic Publication: 2024 Aug 20.

T-cell deficiency and hyperinflammatory monocyte responses associate with Mycobacterium avium complex lung disease.

Autor: Lindestam Arlehamn CS; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States., Benson B; Department of Medicine, University of Washington, Seattle, WA, United States., Kuan R; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States., Dill-McFarland KA; Department of Medicine, University of Washington, Seattle, WA, United States., Peterson GJ; Department of Medicine, University of Washington, Seattle, WA, United States., Paul S; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States., Nguyen FK; Department of Medicine, University of Washington, Seattle, WA, United States., Gilman RH; Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, United States.; Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Peru., Saito M; Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan., Taplitz R; Department of Medicine, City of Hope National Medical Center, Duarte, CA, United States., Arentz M; Department of Global Health, University of Washington, Seattle, WA, United States.; FIND, the global alliance for diagnostics, Geneva, Switzerland., Goss CH; Department of Medicine, University of Washington, Seattle, WA, United States., Aitken ML; Department of Medicine, University of Washington, Seattle, WA, United States., Horne DJ; Department of Medicine, University of Washington, Seattle, WA, United States.; Department of Global Health, University of Washington, Seattle, WA, United States., Shah JA; Department of Medicine, University of Washington, Seattle, WA, United States.; VA Puget Sound Healthcare System, Seattle, WA, United States., Sette A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States.; Department of Medicine, University of California San Diego, La Jolla, CA, United States., Hawn TR; Department of Medicine, University of Washington, Seattle, WA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Oct 03; Vol. 13, pp. 1016038. Date of Electronic Publication: 2022 Oct 03 (Print Publication: 2022).

Mycobacterium tuberculosis infection, immune activation, and risk of HIV acquisition.

Autor: Bender Ignacio RA; Department of Medicine, University of Washington, Seattle, WA, United States of America.; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America., Long J; Department of Medicine, University of Washington, Seattle, WA, United States of America., Saha A; Department of Medicine, University of Washington, Seattle, WA, United States of America., Nguyen FK; Department of Medicine, University of Washington, Seattle, WA, United States of America., Joudeh L; Department of Medicine, University of Washington, Seattle, WA, United States of America., Valinetz E; Department of Medicine, University of Washington, Seattle, WA, United States of America., Mendelsohn SC; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa., Scriba TJ; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa., Hatherill M; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa., Janes H; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America., Churchyard G; Aurum Institute, Parktown, South Africa.; School of Public Health, University of Witwatersrand, Johannesburg, South Africa.; Department of Medicine, Vanderbilt University, Nashville, TN, United States of America., Buchbinder S; San Francisco Department of Public Health and Departments of Medicine and Epidemiology, University of California San Francisco, San Francisco, CA, United States of America., Duerr A; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America., Shah JA; Department of Medicine, University of Washington, Seattle, WA, United States of America.; Veteran Affairs Puget Sound Healthcare System, Seattle, WA, United States of America., Hawn TR; Department of Medicine, University of Washington, Seattle, WA, United States of America.

Publikováno v: PloS one [PLoS One] 2022 May 03; Vol. 17 (5), pp. e0267729. Date of Electronic Publication: 2022 May 03 (Print Publication: 2022).

Non-IFNγ Whole Blood Cytokine Responses to Mycobacterium tuberculosis Antigens in HIV-exposed Infants.

Autor: Anterasian C; From the Department of Pediatrics, University of Washington, Seattle, Washington., Warr AJ; Department of Medicine, University of Washington, Seattle, Washington., Lacourse SM; Department of Medicine, University of Washington, Seattle, Washington.; Department of Global Health, University of Washington, Seattle, Washington., Kinuthia J; Department of Research and Programs, Kenyatta National Hospital, Nairobi, Kenya., Richardson BA; Department of Global Health, University of Washington, Seattle, Washington.; Department of Biostatistics, University of Washington, Seattle, Washington., Nguyen FK; Department of Medicine, University of Washington, Seattle, Washington., Matemo D; Department of Research and Programs, Kenyatta National Hospital, Nairobi, Kenya., Maleche-Obimbo E; Department of Pediatrics and Child Health, Kenyatta National Hospital, Nairobi, Kenya., John Stewart GC; Department of Medicine, University of Washington, Seattle, Washington., Hawn TR; Department of Medicine, University of Washington, Seattle, Washington.

Publikováno v: The Pediatric infectious disease journal [Pediatr Infect Dis J] 2021 Oct 01; Vol. 40 (10), pp. 922-929.

Monocyte metabolic transcriptional programs associate with resistance to tuberculin skin test/interferon-γ release assay conversion.

Autor: Simmons JD; TB Research and Training Center, Department of Medicine, University of Washington, Seattle, Washington, USA., Van PT; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Stein CM; Department of Population & Quantitative Health Sciences and.; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Chihota V; School of Public Health, University of Witwatersrand, Johannesburg, South Africa.; The Aurum Institute, Parktown, South Africa., Ntshiqa T; The Aurum Institute, Parktown, South Africa., Maenetje P; The Aurum Institute, Parktown, South Africa., Peterson GJ; TB Research and Training Center, Department of Medicine, University of Washington, Seattle, Washington, USA., Reynolds A; TB Research and Training Center, Department of Medicine, University of Washington, Seattle, Washington, USA., Benchek P; Department of Population & Quantitative Health Sciences and., Velen K; The Aurum Institute, Parktown, South Africa., Fielding KL; School of Public Health, University of Witwatersrand, Johannesburg, South Africa.; TB Centre, London School of Hygiene and Tropical Medicine, London, United Kingdom., Grant AD; School of Public Health, University of Witwatersrand, Johannesburg, South Africa.; TB Centre, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Africa Health Research Institute, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa., Graustein AD; TB Research and Training Center, Department of Medicine, University of Washington, Seattle, Washington, USA., Nguyen FK; TB Research and Training Center, Department of Medicine, University of Washington, Seattle, Washington, USA., Seshadri C; TB Research and Training Center, Department of Medicine, University of Washington, Seattle, Washington, USA., Gottardo R; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Mayanja-Kizza H; Department of Medicine, School of Medicine, Makerere University, Kampala, Uganda., Wallis RS; The Aurum Institute, Parktown, South Africa., Churchyard G; The Aurum Institute, Parktown, South Africa., Boom WH; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Hawn TR; TB Research and Training Center, Department of Medicine, University of Washington, Seattle, Washington, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Jul 15; Vol. 131 (14).