Unbiased Screens Show CD8 ⁺ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein.

Autor: Ferretti AP; TScan Therapeutics, Waltham, MA 02451, USA., Kula T; TScan Therapeutics, Waltham, MA 02451, USA., Wang Y; TScan Therapeutics, Waltham, MA 02451, USA., Nguyen DMV; TScan Therapeutics, Waltham, MA 02451, USA., Weinheimer A; TScan Therapeutics, Waltham, MA 02451, USA., Dunlap GS; TScan Therapeutics, Waltham, MA 02451, USA., Xu Q; TScan Therapeutics, Waltham, MA 02451, USA., Nabilsi N; TScan Therapeutics, Waltham, MA 02451, USA., Perullo CR; TScan Therapeutics, Waltham, MA 02451, USA., Cristofaro AW; TScan Therapeutics, Waltham, MA 02451, USA., Whitton HJ; TScan Therapeutics, Waltham, MA 02451, USA., Virbasius A; TScan Therapeutics, Waltham, MA 02451, USA., Olivier KJ Jr; TScan Therapeutics, Waltham, MA 02451, USA., Buckner LR; Ochsner Medical Center, New Orleans, LA 70121, USA., Alistar AT; Atlantic Health System, Morristown, NJ 07960, USA., Whitman ED; Atlantic Health System, Morristown, NJ 07960, USA., Bertino SA; TScan Therapeutics, Waltham, MA 02451, USA., Chattopadhyay S; TScan Therapeutics, Waltham, MA 02451, USA., MacBeath G; TScan Therapeutics, Waltham, MA 02451, USA. Electronic address: gmacbeath@tscan.com.

Publikováno v: Immunity [Immunity] 2020 Nov 17; Vol. 53 (5), pp. 1095-1107.e3. Date of Electronic Publication: 2020 Oct 20.