Molecular characterization of the interaction between peripherin-2 and opsins in rod and cone photoreceptors

Autor: Nguyen, Ong Nam Phuong

The tetraspanin peripherin-2 is a glyco-membrane protein exclusively expressed in the outer segments of rod and cone photoreceptors. Mutations in peripherin-2 are associated with retinal disorders characterized by Degeneration of rod or cone cells. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8eba51d1a1345e5d5fb5c976e4bd99b2

Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.

Autor: Gerndt S; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany.; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Chen CC; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany., Chao YK; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Yuan Y; Department of Cell and Developmental Biology, University College London, London, United Kingdom., Burgstaller S; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Scotto Rosato A; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Krogsaeter E; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Urban N; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Universität Leipzig, Leipzig, Germany., Jacob K; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Nguyen ONP; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany., Miller MT; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany.; Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland., Keller M; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany., Vollmar AM; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany., Gudermann T; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Zierler S; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Schredelseker J; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany.; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Schaefer M; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany.; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Universität Leipzig, Leipzig, Germany., Biel M; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany., Malli R; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Wahl-Schott C; Institute for Neurophysiology, Hannover Medical School, Hannover, Germany., Bracher F; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität, Munich, Germany., Patel S; Department of Cell and Developmental Biology, University College London, London, United Kingdom., Grimm C; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich, Germany.

Publikováno v: ELife [Elife] 2020 Mar 16; Vol. 9. Date of Electronic Publication: 2020 Mar 16.