Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition.

Autor: Filion ML; Department of Pathology and Molecular Medicine, McMaster University, HSC-4N66, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada., Bhakta V, Nguyen LH, Liaw PS, Sheffield WP

Publikováno v: Biochemistry [Biochemistry] 2004 Nov 23; Vol. 43 (46), pp. 14864-72.