Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ngonidzashe B. Madungwe"'
Autor:
Abdulhafiz Imam Aliagan, Ngonidzashe B. Madungwe, Nathalie Tombo, Yansheng Feng, Jean C. Bopassa
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Introduction: Estrogen (17β-estradiol, E2) is well-known to induce cardioprotective effects against ischemia/reperfusion (I/R) injury. We recently reported that acute application of E2 at the onset of reperfusion in vivo induces cardioprotective eff
Externí odkaz:
https://doaj.org/article/ec8651b3c30c42fdba95c2a004716173
Autor:
Ngonidzashe B Madungwe, Yansheng Feng, Jean C. Bopassa, Nathalie Tombo, Abdulhafiz Imam Aliagan
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology, Vol 11 (2020)
Introduction: Estrogen (17β-estradiol, E2) is well-known to induce cardioprotective effects against ischemia/reperfusion (I/R) injury. We recently reported that acute application of E2 at the onset of reperfusion in vivo induces cardioprotective eff
Publikováno v:
British Journal of Pharmacology. 174:4329-4344
Background and Purpose Recent evidence indicates that GPER (G protein-coupled oestrogen receptor 1) mediates acute pre-ischaemic oestrogen-induced protection of the myocardium from ischaemia/reperfusion injury via a signalling cascade that includes P
Autor:
Yansheng Feng, Nathalie Tombo, Ngonidzashe B. Madungwe, Abdulhafiz Imam Aliagan, Jean C. Bopassa
Publikováno v:
Biochem Biophys Res Commun
Ferroptosis is a distinct iron-dependent mechanism of regulated cell death recognized in cancer and ischemia/reperfusion (I/R) injury of different organs. It has been reported that molecules such as liproxstatin-1 (Lip-1) inhibit ferroptosis and prom
Publikováno v:
Circulation Research. 125
Introduction: We recently showed that cardiac tissue treated acutely with estrogen (17β-estradiol; E2), pre- and post-ischemia, exhibited reduced myocardial infarct size and better functional recovery after ischemia /reperfusion via the G protein-co
Autor:
Li Liu, Yansheng Feng, Abdulhafiz Imam Aliagan, Nathalie Tombo, Ngonidzashe B. Madungwe, Jean C. Bopassa
Publikováno v:
Circulation Research. 125
Introduction: Ferroptosis is a non-apoptotic form of cell death characterized by iron-dependent accumulation of lethal lipid reactive oxygen species (ROS) and liproxstatin-1 is a potent inhibitor of ferroptosis. We investigated whether Liproxstatin-1
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Journal of cellular physiology. 234(4)
The identification of the mitochondrial contact site and cristae organizing system (MICOS) in the inner mitochondrial membrane shed light on the intricate components necessary for mitochondria to form their signature cristae in which many protein com
Autor:
Yansheng Feng, Mihaela Lie, Li Liu, Nathalie Tombo, Ferdinand Kaya, Jean C. Bopassa, Ngonidzashe B. Madungwe
Mitofilin is an inner membrane protein that has been defined as a mitochondria-shaping protein in controlling and maintaining mitochondrial cristae structure and remodeling. We determined the role of mitofilin in cell survival by investigating the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b41199549a76ef253d68a082124891
https://europepmc.org/articles/PMC6087732/
https://europepmc.org/articles/PMC6087732/
Publikováno v:
Circulation Research. 121
Introduction: Mitochondrial activity plays an essential role in the efficient function of cardiomyocytes. Mitofilin is an inner membrane protein that has been defined as a mitochondria-shaping protein in controlling and maintaining mitochondrial cris