Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ngocdiep Le"'
Autor:
Cara Haymaker, Aung Naing, Shubham Pant, Minal Barve, Dae Won Kim, Richard Kim, Melissa Johnson, Marya Chaney, Robert Wolff, Jean Fan, Byung Ha Lee, NgocDiep Le, Sara Ferrando-Martinez, Hirva Mamdani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/1b86d5d524b24ac796db83a3f7cc63ce
Autor:
Michael Rettig, Jiayi Huang, Jian Campian, Tanner Johanns, Todd Fehniger, Se Hwan Yang, Milan Chheda, Alice Zhou, Jennifer Foltz, Jingqin Luo, Omar Butt, Chai Avvaru, Ruth Katumba, Albert Kim, Gavin Dunn, Christopher Abraham, Jean Fan, Byung Ha Lee, NgocDiep Le, George Ansstas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/b95a8657d65f4de49bf67fda2aee3b21
Autor:
Cristiana Sessa, Heidi Nauwelaerts, Angela Zubel, Malte Peters, Denes Csonka, David Demanse, Kirsten Carter, Ngocdiep Le, Carolyn D. Britten, Anastasios Stathis, José Pérez-García, Eric Van Cutsem, Johan Vansteenkiste, Luis Paz-Ares, Zev A. Wainberg, Filip Janku, Josep Tabernero, Philippe L. Bedard
Purpose: MAPK and PI3K/AKT/mTOR pathways play important roles in many tumors. In this study, safety, antitumor activity, and pharmacokinetics of buparlisib (pan class PI3K inhibitor) and trametinib (MEK inhibitor) were evaluated.Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061067261f4c813cbf9a18930c3c0970
https://doi.org/10.1158/1078-0432.c.6523926
https://doi.org/10.1158/1078-0432.c.6523926
Autor:
Dae-Won Kim, Cara Haymaker, Marya F. Chaney, Shubham Pant, Melissa Lynne Johnson, Jean Fan, Sara Ferrando-Martinez, Richard Kim, Ngocdiep Le, Aung Naing, Minal A. Barve, Hirva Mamdani, Byung Ha Lee, Robert A. Wolff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundPancreatic cancer (PaC) is immune-quiescent and resistant to single-agent checkpoint inhibitor (CPI). NT-I7 (efineptakin alfa) is the first-in-class long-acting IL-7 that can increase T-cell infiltration in the tumor microenvironment (TME)
Autor:
Byung Ha Lee, Jian Campian, Jingqin Luo, Jiayi Huang, Gavin P. Dunn, Tanner M. Johanns, Se Hwan Yang, Puspanjali Bhatta, Jean Fan, George Ansstas, Albert H. Kim, Christopher Abraham, Ruth Katumba, Milan G. Chheda, Sunita Ranjitka, Chai Avvaru, Ngocdiep Le
Publikováno v:
Journal of Clinical Oncology. 39:2040-2040
2040 Background: High-grade gliomas (HGG) patients can develop prolonged lymphopenia after standard radiation therapy (RT) and temozolomide (TMZ), which has been shown to correlate with worse survival. Interleukin-7 (IL-7) level, a cytokine that stim
Akademický článek
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Autor:
Pier Luigi Zinzani, Carole B. Miller, Stephanie Lustgarten, Kam Sprott, NgocDiep Le, Jonathan A. Pachter, Ian W. Flinn, Kirit M. Ardeshna, David T. Weaver, Nina D. Wagner-Johnston, Scott A. Tetreault
Publikováno v:
Blood. 132:4167-4167
Introduction: Indolent NHL (iNHL) remains largely incurable, with the majority of patients (pts) eventually becoming refractory to standard therapies, necessitating new effective and tolerable treatments. Duvelisib is an oral dual PI3K-δ,γ inhibito
Autor:
Fritz Offner, Klaus Geissler, Matthew S. Davids, Leanne Berkhan, Stephanie Lustgarten, Jose J. Rifon Roca, Julio Delgado, NgocDiep Le, Ian W. Flinn, Zsolt Nagy, Marco Montillo, Zoltán Gasztonyi
Publikováno v:
Blood. 132:3146-3146
Background: Duvelisib (DUV) is a first-in class, oral dual inhibitor of PI3K-δ,-γ being developed for the treatment of advanced B- and T-cell malignancies. To date 304 patients (pts) with relapsed/refractory (RR) CLL/SLL have been treated with DUV
Autor:
Constantine S. Tam, Kam Sprott, Jennifer R. Brown, Zsolt Nagy, Ian W. Flinn, Peter Hillmen, Ulrich Jaeger, Stephan Stilgenbauer, Bryone J. Kuss, Carol Moreno, Jonathan A. Pachter, Marco Montillo, Julio Delgado, NgocDiep Le, Stephanie Lustgarten, Paolo Ghia, Matthew S. Davids, Florence Cymbalista, David T. Weaver
Publikováno v:
Blood. 132:1856-1856
Introduction In CLL, the timing and selection of therapy is largely informed by disease stage, prognostic molecular features, tumor load, and patient (pt) performance status. Duvelisib (DUV) is a novel, oral, dual PI3K-δ,γ inhibitor in clinical dev
Autor:
Jessica Son, John F. Whitesides, Divino Deoliveira, Benny J. Chen, NgocDiep Le, Xiuyu Cui, Nelson J. Chao
Publikováno v:
Blood. 109:3115-3123
Several groups, including our own, have independently demonstrated that effector memory T cells from non–alloantigen-primed donors do not cause graft-versus-host disease (GVHD). In the current study, we further investigated whether this approach co