Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ngoc-Nga Vinh"'
Autor:
Stephanie J. Hanna, Terri C. Thayer, Emma J. S. Robinson, Ngoc-Nga Vinh, Nigel Williams, Laurie G. Landry, Robert Andrews, Qi Zhuang Siah, Pia Leete, Rebecca Wyatt, Martina A. McAteer, Maki Nakayama, F. Susan Wong, Jennie H. M. Yang, Timothy I. M. Tree, Johnny Ludvigsson, Colin M. Dayan, Danijela Tatovic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Gold nanoparticles (GNPs) have been used in the development of novel therapies as a way of delivery of both stimulatory and tolerogenic peptide cargoes. Here we report that intradermal injection of GNPs loaded with the proinsulin peptide C19-A3, in p
Externí odkaz:
https://doaj.org/article/53e6f7919fde4d98856728343312e345
Autor:
David J. Harrison, Victoria H. Roberton, Ngoc-Nga Vinh, Simon P. Brooks, Stephen B. Dunnett, Anne E. Rosser
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Huntington's disease (HD) is a progressive neurodegenerative disease in which striatal medium spiny neurons (MSNs) are lost. Neuronal replacement therapies aim to replace MSNs through striatal transplantation of donor MSN progenitors, which successfu
Externí odkaz:
https://doaj.org/article/37735d1079ca490b8c3cc13d9b9eebdd
Autor:
Mariah J. Lelos, Victoria H. Roberton, Ngoc-Nga Vinh, Carl Harrison, Peter Eriksen, Eduardo M. Torres, Susanne P. Clinch, Anne E. Rosser, Stephen B. Dunnett
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Huntington's disease (HD) is a debilitating, genetically inherited neurodegenerative disorder that results in early loss of medium spiny neurons from the striatum and subsequent degeneration of cortical and other subcortical brain regions. Behavioral
Externí odkaz:
https://doaj.org/article/df23e504e51b433fba2083b61469edff
Autor:
Marco Straccia, Gerardo Garcia-Diaz Barriga, Phil Sanders, Georgina Bombau, Jordi Carrere, Pedro Belio Mairal, Ngoc-Nga Vinh, Sun Yung, Claire M Kelly, Clive N Svendsen, Paul J Kemp, Jamshid Arjomand, Ryan C Schoenfeld, Jordi Alberch, Nicholas D Allen, Anne E Rosser, Josep M Canals
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
A systematic characterization of the spatio-temporal gene expression during human neurodevelopment is essential to understand brain function in both physiological and pathological conditions. In recent years, stem cell technology has provided an in v
Externí odkaz:
https://doaj.org/article/a9286052aa584356b06eb800c8941e2b
Autor:
Darren Cameron, Da Mi, Ngoc-Nga Vinh, Caleb Webber, Meng Li, Oscar Marín, Michael C. O’Donovan, Nicholas J. Bray
Background\udWhile a variety of evidence supports a prenatal component to schizophrenia, there are few data regarding the cell populations involved. We sought to identify cells of the human prenatal brain mediating genetic risk for schizophrenia by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1e19d964a05e9ae6a6469f1b9105e8
https://orca.cardiff.ac.uk/id/eprint/151244/1/PIIS0006322322014044.pdf
https://orca.cardiff.ac.uk/id/eprint/151244/1/PIIS0006322322014044.pdf
Autor:
Ngoc-Nga Vinh, Ana Garcia, Anne Elizabeth Rosser, Oliver J.M. Bartley, Nigel Williams, Sophie Victoria Precious, Victoria H. Roberton, Christian Schnell, Paul J. Kemp, Narawadee Choompoo, Claire Kelly
Publikováno v:
Cytotherapy
Background\ud Cell replacement therapy (CRT) for Huntington disease (HD) requires a source of striatal (STR) progenitors capable of restoring the function lost due to STR degeneration. Authentic STR progenitors can be collected from the fetal putativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2522f84cfab752648295a4e6a12ab8
https://orca.cardiff.ac.uk/id/eprint/137641/1/PIIS146532492030760X.pdf
https://orca.cardiff.ac.uk/id/eprint/137641/1/PIIS146532492030760X.pdf
Autor:
David Brown, Mónica Pardo, Polina Yarova, Sun Yung, Josep M. Canals, Jonathan T. Brown, Jane M. Hancock, Vsevolod Telezhkin, Nicholas D. Allen, Anne Elizabeth Rosser, Ngoc Nga Vinh, Paul J. Kemp, Gerardo García-Díaz Barriga, Andrew D. Randall, Marco Straccia
Publikováno v:
Pflugers Archiv
Telezhkin, V, Straccia, M, Yarova, P, Pardo, M, Yung, S, Vinh, N N, Hancock, J M, Barriga, G G D, Brown, D A, Rosser, A E, Brown, J T, Canals, J M, Randall, A D, Allen, N D & Kemp, P J 2018, ' Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons ', Pflügers Archiv: European Journal of Physiology . https://doi.org/10.1007/s00424-018-2155-7
Telezhkin, V, Straccia, M, Yarova, P, Pardo, M, Yung, S, Vinh, N N, Hancock, J M, Barriga, G G D, Brown, D A, Rosser, A E, Brown, J T, Canals, J M, Randall, A D, Allen, N D & Kemp, P J 2018, ' Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons ', Pflügers Archiv: European Journal of Physiology . https://doi.org/10.1007/s00424-018-2155-7
Kv7 channels determine the resting membrane potential of neurons and regulate their excitability. Even though dysfunction of Kv7 channels has been linked to several debilitating childhood neuronal disorders, the ontogeny of the constituent genes, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e020e206e8d595605fbd5296feeb145
https://orca.cardiff.ac.uk/id/eprint/111917/1/s00424-018-2155-7.pdf
https://orca.cardiff.ac.uk/id/eprint/111917/1/s00424-018-2155-7.pdf
Autor:
Ngoc-Nga Vinh, David S. Williams, James A. H. Murray, Mutwakil Abdulla, Ying Zhu, William A. Gray, Amit P. Jathoul, Anne Elizabeth Rosser, E. Messaritaki
Publikováno v:
Experimental therapeutics – preclinical.
Background Efforts in cell replacement therapy for Huntington’s disease (HD) are hindered by uncertainty of graft fate after transplantation. Current cell tracking methods fall short to either: 1) Detect labelled transplanted cells, or 2) Different
Autor:
Marija Fjodorova, Anne Elizabeth Rosser, Meng Li, Marie Michael, Ana Garcia, Aurore Bugi, Stephen B. Dunnett, Anselme L. Perrier, Ngoc-Nga Vinh, Mariah Jillian Lelos
Publikováno v:
Experimental therapeutics – preclinical.
Cell replacement therapies in Huntington’s disease (HD) aim to repair the nervous system by reintroducing the previously degenerated medium spiny neurons (MSNs) of the striatum and thereby restoring efferent and afferent projections. Despite signif
Autor:
Rike Zietlow, Ngoc-Nga Vinh, Inés Guardia, Mónica Pardo, Cristina Herranz, Josep M. Canals, Anne Elizabeth Rosser, Raquel Martín-Ibáñez
Publikováno v:
Experimental Neurology
Primary human fetal cells have been used in clinical trials of cell replacement therapy for the treatment of neurodegenerative disorders such as Huntington's disease (HD). However, human fetal primary cells are scarce and difficult to work with and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963c41d405de32a103cc05d30d80ee84
https://hdl.handle.net/11858/00-001M-0000-002D-25DB-4
https://hdl.handle.net/11858/00-001M-0000-002D-25DB-4