Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ngoc-Han Ha"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Breast cancer is the most frequently diagnosed cancer worldwide, constituting 15% of cases in 2023. The predominant cause of breast cancer-related mortality is metastasis, and a lack of metastasis-targeted therapies perpetuates dismal outcom
Externí odkaz:
https://doaj.org/article/aa03e11f096f45bca2a6989e6e53387a
Autor:
Megan R Majocha, Devin E Jackson, Ngoc-Han Ha, Ruhul Amin, Marie Pangrácová, Christina R Ross, Howard H Yang, Maxwell P Lee, Kent W Hunter
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011236 (2024)
Patients with ER-negative breast cancer have the worst prognosis of all breast cancer subtypes, often experiencing rapid recurrence or progression to metastatic disease shortly after diagnosis. Given that metastasis is the primary cause of mortality
Externí odkaz:
https://doaj.org/article/6290cedd334c4525803ae30e670a3c1c
Autor:
Benjamin Harris, Suman Vodnala, Yogin Patel, Gary Lee, Shobha Potluri, Melissa Bedard, Carson Harms, Melissa DeFrancesco, Jaewon Yun, Saeed Azimi, Ngoc-Han Ha, Audrey Garces
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/47d7d6be219c4b39869e456b28bc2541
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006267 (2016)
Breast cancer mortality is primarily due to metastasis rather than primary tumors, yet relatively little is understood regarding the etiology of metastatic breast cancer. Previously, using a mouse genetics approach, we demonstrated that inherited ger
Externí odkaz:
https://doaj.org/article/19fd0e6cf7114e01990a8b893412bb22
An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes.
Autor:
Ling Bai, Howard H Yang, Ying Hu, Anjali Shukla, Ngoc-Han Ha, Anthony Doran, Farhoud Faraji, Natalie Goldberger, Maxwell P Lee, Thomas Keane, Kent W Hunter
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005989 (2016)
Metastasis remains the primary cause of patient morbidity and mortality in solid tumors and is due to the action of a large number of tumor-autonomous and non-autonomous factors. Here we report the results of a genome-wide integrated strategy to iden
Externí odkaz:
https://doaj.org/article/1816e5d744d14a5f959481a75fcc1a52
Autor:
Thomas R Geiger, Ngoc-Han Ha, Farhoud Faraji, Helen T Michael, Loren Rodriguez, Renard C Walker, Jeffery E Green, R Mark Simpson, Kent W Hunter
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111813 (2014)
Identification of conserved co-expression networks is a useful tool for clustering groups of genes enriched for common molecular or cellular functions [1]. The relative importance of genes within networks can frequently be inferred by the degree of c
Externí odkaz:
https://doaj.org/article/53b5b58e6454453cb37f2489165f3e63
Autor:
Jude Alsarraj, Farhoud Faraji, Thomas R Geiger, Katherine R Mattaini, Mia Williams, Josephine Wu, Ngoc-Han Ha, Tyler Merlino, Renard C Walker, Allen D Bosley, Zhen Xiao, Thorkell Andresson, Dominic Esposito, Nicholas Smithers, Dave Lugo, Rab Prinjha, Anup Day, Nigel P S Crawford, Keiko Ozato, Kevin Gardner, Kent W Hunter
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80746 (2013)
Recent studies suggest that BET inhibitors are effective anti-cancer therapeutics. Here we show that BET inhibitors are effective against murine primary mammary tumors, but not pulmonary metastases. BRD4, a target of BET inhibitors, encodes two isofo
Externí odkaz:
https://doaj.org/article/c2c9aa744b3a4146a566e38515814caa
Autor:
Rakesh Kumar, George C. Prendergast, Margaretha Wallon, Suzanne Fuqua, Rajendra A. Badwe, Allan Lipton, Luis Costa, Da-Qiang Li, Suresh B. Pakala, Krishna Sumanth Ghanta, Kazufumi Ohshiro, Prakriti Mudvari, Divijendra Natha Sirigiri Reddy, Vasudha S. Nair, Ngoc-Han Ha
Triple-negative breast cancer (TNBC) is characterized by the lack of expression of estrogen receptor-α (ER-α), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER-2). However, pathways responsible for downregulation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0775575f44e2a815ed862233ae47f778
https://doi.org/10.1158/0008-5472.c.6503081.v1
https://doi.org/10.1158/0008-5472.c.6503081.v1
Autor:
Benjamin Harris, Yogin Patel, Ngoc-Han Ha, Lora Zhao, Sheila Lou, Stefan Siebert, Emily Fu-Sum, Rigel Kishton, Purnima Sundar, Suman Kumar Vodnala, Shobha Potluri
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Naritaka Tamaoki, Stefan Siebert, Takuya Maeda, Ngoc-Han Ha, Meghan L. Good, Yin Huang, Suman K. Vodnala, Juan J. Haro-Mora, Naoya Uchida, John F. Tisdale, Colin L. Sweeney, Uimook Choi, Julie Brault, Sherry Koontz, Harry L. Malech, Yasuhiro Yamazaki, Risa Isonaka, David S. Goldstein, Masaki Kimura, Takanori Takebe, Jizhong Zou, David F. Stroncek, Pamela G. Robey, Michael J. Kruhlak, Nicholas P. Restifo, Raul Vizcardo
Publikováno v:
Cell Reports Methods. 3:100460