Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ngoc T. Ha"'
Autor:
D. Leonardo Garcia-Ramirez, Shayna Singh, Jenna R. McGrath, Ngoc T. Ha, Kimberly J. Dougherty
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Spinal cord neurons integrate sensory and descending information to produce motor output. The expression of transcription factors has been used to dissect out the neuronal components of circuits underlying behaviors. However, most of the canonical po
Externí odkaz:
https://doaj.org/article/bb354c995e034efcaa8556f83b5b97eb
Neural Interactions in Developing Rhythmogenic Spinal Networks: Insights From Computational Modeling
Publikováno v:
Frontiers in Neural Circuits, Vol 14 (2020)
The mechanisms involved in generation of rhythmic locomotor activity in the mammalian spinal cord remain poorly understood. These mechanisms supposedly rely on both intrinsic properties of constituting neurons and interactions between them. A subset
Externí odkaz:
https://doaj.org/article/ccb111d1645c469cab645739e9f1e09d
Autor:
Ngoc T Ha, Kimberly J Dougherty
Publikováno v:
eLife, Vol 7 (2018)
Neuronal networks generating hindlimb locomotion are located in the spinal cord. The mechanisms underlying spinal rhythmogenesis are unknown but network activity and interconnectivity of excitatory interneurons likely play prominent roles. Here, we i
Externí odkaz:
https://doaj.org/article/3aaa98380d854b198104bc4f9a18f5b7
Publikováno v:
Neurosci Bull
Autor:
Steve Bibu, Nicholas J Stachowski, Kimberly J. Dougherty, Ngoc T Ha, D Leonardo Garcia-Ramirez
Publikováno v:
J Neurosci
Neural circuitry generating locomotor rhythm and pattern is located in the spinal cord. Most spinal cord injuries (SCIs) occur above the level of spinal locomotor neurons; therefore, these circuits are a target for improving motor function after SCI.
Autor:
Sarah A. Bennison, Sara M. Blazejewski, Ngoc T Ha, Xiaonan Liu, Trevor H. Smith, Kazuhito Toyo-oka, Kimberly J. Dougherty
Publikováno v:
Cereb Cortex
Neuromorphological defects underlie neurodevelopmental disorders and functional defects. We identified a function for Rpsa in regulating neuromorphogenesis using in utero electroporation to knockdown Rpsa, resulting in apical dendrite misorientation,
Autor:
Kimberly J. Dougherty, Xiaonan Liu, Sarah A. Bennison, Kazuhito Toyo-oka, Sara M. Blazejewski, Trevor H. Smith, Ngoc T Ha
Neuromorphological defects underlie neurodevelopmental disorders and functional defects. We identified a function for ribosomal protein SA (Rpsa) in regulating neuromorphogenesis using in utero electroporation to knockdown Rpsa, which results in apic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba80fb6ef8924ab0d436b0792d79a528
Autor:
Ngoc T Ha, Kimberly J. Dougherty
Publikováno v:
Current opinion in physiology. 8
To initiate and support locomotion, rhythm generating neurons in the spinal central pattern generator convert descending input into a rhythmic signal which is conveyed to downstream neurons, leading to the recruitment of motor neurons and the activat
Autor:
Megan A. Frederick, Masahide Asano, Ngoc T Ha, Michael Sun, Rani E. George, Duc-Hung Pham, Chie Naruse, To-Ha Thai, Matthew E. Pipkin, Bandana Sharma
Publikováno v:
Scientific Reports
Cbx3/HP1γ is a histone reader whose function in the immune system is not completely understood. Here, we demonstrate that in CD8+ T cells, Cbx3/HP1γ insufficiency leads to chromatin remodeling accompanied by enhanced Prf1, Gzmb and Ifng expression.