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The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1

Autor: Ngo, Greg H. P., Balakrishnan, Lata, Dubarry, Marion, Campbell, Judith L., Lydall, David

Single-stranded DNA (ssDNA) at DNA ends is an important regulator of the DNA damage response. Resection, the generation of ssDNA, affects DNA damage checkpoint activation, DNA repair pathway choice, ssDNA-associated mutation and replication fork stab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od________38::f3bc9283d82a396dee3bd64801aa67ec
https://resolver.caltech.edu/CaltechAUTHORS:20140820-085638030

The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.

Autor: Ngo GH; Institute for Cell and Molecular Biosciences (ICaMB), Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Balakrishnan L; Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA., Dubarry M; Institute for Cell and Molecular Biosciences (ICaMB), Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Campbell JL; Divisions of Biology and Chemistry, Caltech, Braun Laboratories, Pasadena, CA 91125, USA., Lydall D; Institute for Cell and Molecular Biosciences (ICaMB), Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK d.a.lydall@ncl.ac.uk.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2014; Vol. 42 (16), pp. 10516-28. Date of Electronic Publication: 2014 Aug 13.